Hao yang Zhang

Prof. Dr. Hao yang Zhang

orcid

Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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20 October 2023 in Medicine
Verified
Journal Article
Open access
YPYingsen Bs Pan
Yingsen Bs Pan
HZHao yang Zhang
Hao yang Zhang
XYXin Ye
Xin Ye
SLShuailin Li
Shuailin Li
XLXiaoming Li
Xiaoming Li
XYXiaoming Ying
Xiaoming Ying
Adolescent scoliosis is one of the most common surgical disorders of the pediatric spine. With timely detection and early treatment, most scoliotic children can avoid major and expensive surgery. Vision problems are also frequently found at an early age and can take a toll on individuals quality of life. However, scoliosis, a severe health hazard to adolescents, is often accompanied by vision problems clinically, including myopia, astigmatism, strabismus, amblyopia, horizontal paralysis, and blindness. And people with genetic defects have a higher probability of suffering both spinal problems and vision problems than those with nongenetic defects. However, many individuals viewed scoliosis and vision problems as 2 irrelevant diseases. This review searched PubMed, China National Knowledge Infrastructure, and Web of Science for studies on adolescent, scoliosis, eye diseases, myopia, strabismus, spinal disorders, and vision problems for almost 3 decades, and thus confirmed the potential relationship between adolescent scoliosis and vision problems.

24 September 2026 in PLOS ONE
Verified
Journal Article
Open access
PDF file
GCGe Cai
Ge Cai
YSYi Sun
Yi Sun
SYShuaizi Yin
Shuaizi Yin
SYShuaiyu Ying
Shuaiyu Ying
HLHuasong Luo
Huasong Luo
HZHao yang Zhang
Hao yang Zhang
Background: Atlantoaxial rotatory subluxation (AARS) is a common cause of acquired painful torticollis in children. Conservative treatment is widely used, but high-quality randomized evidence for structured muscle-focused rehabilitation is limited. Musculoskeletal ultrasound, especially shear-wave elastography (SWE), can measure cervical muscle stiffness in a non-invasive way. This trial aims to test the efficacy and safety of joint mobilization combined with cervical resistance training in children with AARS. It will also examine whether ultrasound-based measures can detect treatment-related changes in cervical muscle stiffness. Methods: This is a single-center, assessor- and analyst-blinded, randomized controlled superiority trial with two parallel groups. Seventy children aged 2–18 years with clinically and radiologically confirmed AARS will be randomly assigned in a 1:1 ratio to joint mobilization plus cervical resistance training or joint mobilization alone. Both groups will receive treatment 3 times per week for 4 weeks. The primary outcome is affected-side sternocleidomastoid stiffness at week 4 measured by SWE and adjusted for baseline stiffness. Secondary outcomes include bilateral sternocleidomastoid and upper trapezius SWE parameters, pain intensity, cervical disability, cervical rotation range of motion, overall clinical efficacy, and recurrence-related outcomes. SWE outcomes will be assessed at baseline, week 2, and week 4. Pain and disability outcomes will be assessed at baseline, week 2, week 4, and at 3 and 6 months after treatment. Cervical rotation range of motion will be assessed at baseline, week 2, and week 4. Recurrence-related outcomes will be recorded at the 3- and 6-month follow-up visits. Discussion: This randomized controlled trial is designed to provide high-quality evidence regarding the effectiveness of joint mobilization combined with cervical resistance training for pediatric AARS. By incorporating musculoskeletal ultrasound as an objective assessment tool, the study aims to elucidate the relationship between cervical muscle mechanical properties and clinical outcomes. The findings may contribute to the development of standardized, muscle-focused conservative treatment strategies for children with AARS. Trial registration: International Traditional Medicine Clinical Trial Registry ( ITMCTR2025002448 ), registered on 27 October 2025.

Verified
Open access
PDF file
GCGe Cai
Ge Cai
YSYi Sun
Yi Sun
SYShuaizi Yin
Shuaizi Yin
SYShuaiyu Ying
Shuaiyu Ying
HLHuasong Luo
Huasong Luo
HZHao yang Zhang
Hao yang Zhang
Background Atlantoaxial rotatory subluxation (AARS) is a common cause of acquired painful torticollis in children. Conservative treatment is widely used, but high-quality randomized evidence for structured muscle-focused rehabilitation is limited. Musculoskeletal ultrasound, especially shear-wave elastography (SWE), can measure cervical muscle stiffness in a non-invasive way. This trial aims to test the efficacy and safety of joint mobilization combined with cervical resistance training in children with AARS. It will also examine whether ultrasound-based measures can detect treatment-related changes in cervical muscle stiffness. Methods This is a single-center, assessor- and analyst-blinded, randomized controlled superiority trial with two parallel groups. Seventy children aged 2–18 years with clinically and radiologically confirmed AARS will be randomly assigned in a 1:1 ratio to joint mobilization plus cervical resistance training or joint mobilization alone. Both groups will receive treatment 3 times per week for 4 weeks. The primary outcome is affected-side sternocleidomastoid stiffness at week 4 measured by SWE and adjusted for baseline stiffness. Secondary outcomes include bilateral sternocleidomastoid and upper trapezius SWE parameters, pain intensity, cervical disability, cervical rotation range of motion, overall clinical efficacy, and recurrence-related outcomes. SWE outcomes will be assessed at baseline, week 2, and week 4. Pain and disability outcomes will be assessed at baseline, week 2, week 4, and at 3 and 6 months after treatment. Cervical rotation range of motion will be assessed at baseline, week 2, and week 4. Recurrence-related outcomes will be recorded at the 3- and 6-month follow-up visits. Discussion This randomized controlled trial is designed to provide high-quality evidence regarding the effectiveness of joint mobilization combined with cervical resistance training for pediatric AARS. By incorporating musculoskeletal ultrasound as an objective assessment tool, the study aims to elucidate the relationship between cervical muscle mechanical properties and clinical outcomes. The findings may contribute to the development of standardized, muscle-focused conservative treatment strategies for children with AARS. Trial registration International Traditional Medicine Clinical Trial Registry (ITMCTR2025002448), registered on 27 October 2025.

19 January 2026 in Scientific Reports
Verified
Journal Article
Open access
PDF file
JTJunsong Tian
Junsong Tian
XYXiaoming Ying
Xiaoming Ying
XYXin Ye
Xin Ye
SAShouwei An
Shouwei An
HZHao yang Zhang
Hao yang Zhang
GCGe Cai
Ge Cai
This retrospective observational study quantitatively assessed paraspinal muscle structural changes following Schroth therapy in patients with Adolescent Idiopathic Scoliosis (AIS) using high-frequency musculoskeletal ultrasound (HF-MSKUS), with the aim of characterizing short-term morphological adaptations associated with this standardized intervention. Fifty AIS patients completed 12 weeks of Schroth training (January 2024–January 2025). Inclusion criteria included AIS (Cobb angle > 10°) with an apical vertebra between T10–L2. HF-MSKUS measured bilateral transverse diameter (TD), anteroposterior diameter (APD), perimeter (P), and cross-sectional area (CSA) at the upper-end, apical, and lower-end vertebral levels before and after training. Prior to treatment, typical muscular asymmetry was observed, characterized by relative convex-side atrophy and compensatory hypertrophy on the concave side. Following Schroth training, significant pre–post changes in paraspinal muscle morphology were detected at all measured levels. At the upper-end vertebra, convex-side TD, APD, P, and CSA increased significantly after intervention (all p < 0.001). At the apical vertebra, convex-side CSA showed a significant increase (ΔCSA ≈ + 0.53 mm², p < 0.01), whereas concave-side CSA decreased significantly (ΔCSA ≈ − 0.44 mm², p < 0.01), indicating a redistribution of bilateral paraspinal muscle morphology. At the lower-end vertebra, convex-side CSA increased (ΔCSA ≈ + 0.51 mm²) and concave-side CSA showed a mild reduction (ΔCSA ≈ − 0.44 mm²), with statistically significant pre–post differences (p < 0.01).In severity-based subgroup analyses, significant pre–post changes in paraspinal muscle morphology were observed within both mild and moderate–severe groups. However, due to the limited sample size in the moderate–severe subgroup, quantitative comparisons between severity strata should be interpreted cautiously. HF-MSKUS proved to be a feasible, radiation-free modality for serial assessment of paraspinal muscle structure in AIS. These findings demonstrate measurable short-term morphological adaptations of the paraspinal muscles following 12 weeks of Schroth therapy, while the functional significance and long-term clinical implications of these changes warrant further investigation.

Verified
Open access
PDF file
GCGe Cai
Ge Cai
YSYi Sun
Yi Sun
SYShuaizi Yin
Shuaizi Yin
SYShuaiyu Ying
Shuaiyu Ying
HLHuasong Luo
Huasong Luo
HZHao yang Zhang
Hao yang Zhang
Background Atlantoaxial rotatory subluxation (AARS) is a common cause of acquired painful torticollis in children. Conservative treatment is widely used, but high-quality randomized evidence for structured muscle-focused rehabilitation is limited. Musculoskeletal ultrasound, especially shear-wave elastography (SWE), can measure cervical muscle stiffness in a non-invasive way. This trial aims to test the efficacy and safety of joint mobilization combined with cervical resistance training in children with AARS. It will also examine whether ultrasound-based measures can detect treatment-related changes in cervical muscle stiffness. Methods This is a single-center, assessor- and analyst-blinded, randomized controlled superiority trial with two parallel groups. Seventy children aged 2–18 years with clinically and radiologically confirmed AARS will be randomly assigned in a 1:1 ratio to joint mobilization plus cervical resistance training or joint mobilization alone. Both groups will receive treatment 3 times per week for 4 weeks. The primary outcome is affected-side sternocleidomastoid stiffness at week 4 measured by SWE and adjusted for baseline stiffness. Secondary outcomes include bilateral sternocleidomastoid and upper trapezius SWE parameters, pain intensity, cervical disability, cervical rotation range of motion, overall clinical efficacy, and recurrence-related outcomes. SWE outcomes will be assessed at baseline, week 2, and week 4. Pain and disability outcomes will be assessed at baseline, week 2, week 4, and at 3 and 6 months after treatment. Cervical rotation range of motion will be assessed at baseline, week 2, and week 4. Recurrence-related outcomes will be recorded at the 3- and 6-month follow-up visits. Discussion This randomized controlled trial is designed to provide high-quality evidence regarding the effectiveness of joint mobilization combined with cervical resistance training for pediatric AARS. By incorporating musculoskeletal ultrasound as an objective assessment tool, the study aims to elucidate the relationship between cervical muscle mechanical properties and clinical outcomes. The findings may contribute to the development of standardized, muscle-focused conservative treatment strategies for children with AARS. Trial registration International Traditional Medicine Clinical Trial Registry (ITMCTR2025002448), registered on 27 October 2025.

Verified
Open access
PDF file
GCGe Cai
Ge Cai
YSYi Sun
Yi Sun
SYShuaizi Yin
Shuaizi Yin
SYShuaiyu Ying
Shuaiyu Ying
HLHuasong Luo
Huasong Luo
HZHao yang Zhang
Hao yang Zhang
Background Atlantoaxial rotatory subluxation (AARS) is a common cause of acquired painful torticollis in children. Conservative treatment is widely used, but high-quality randomized evidence for structured muscle-focused rehabilitation is limited. Musculoskeletal ultrasound, especially shear-wave elastography (SWE), can measure cervical muscle stiffness in a non-invasive way. This trial aims to test the efficacy and safety of joint mobilization combined with cervical resistance training in children with AARS. It will also examine whether ultrasound-based measures can detect treatment-related changes in cervical muscle stiffness. Methods This is a single-center, assessor- and analyst-blinded, randomized controlled superiority trial with two parallel groups. Seventy children aged 2–18 years with clinically and radiologically confirmed AARS will be randomly assigned in a 1:1 ratio to joint mobilization plus cervical resistance training or joint mobilization alone. Both groups will receive treatment 3 times per week for 4 weeks. The primary outcome is affected-side sternocleidomastoid stiffness at week 4 measured by SWE and adjusted for baseline stiffness. Secondary outcomes include bilateral sternocleidomastoid and upper trapezius SWE parameters, pain intensity, cervical disability, cervical rotation range of motion, overall clinical efficacy, and recurrence-related outcomes. SWE outcomes will be assessed at baseline, week 2, and week 4. Pain and disability outcomes will be assessed at baseline, week 2, week 4, and at 3 and 6 months after treatment. Cervical rotation range of motion will be assessed at baseline, week 2, and week 4. Recurrence-related outcomes will be recorded at the 3- and 6-month follow-up visits. Discussion This randomized controlled trial is designed to provide high-quality evidence regarding the effectiveness of joint mobilization combined with cervical resistance training for pediatric AARS. By incorporating musculoskeletal ultrasound as an objective assessment tool, the study aims to elucidate the relationship between cervical muscle mechanical properties and clinical outcomes. The findings may contribute to the development of standardized, muscle-focused conservative treatment strategies for children with AARS. Trial registration International Traditional Medicine Clinical Trial Registry (ITMCTR2025002448), registered on 27 October 2025.