Meenakshi S

Dr. Meenakshi S

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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4 January 2022 in Gels
Verified
Journal Article
Open access
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MSMeenakshi S
Meenakshi S
AGAnil Kumar Gujjari
Anil Kumar Gujjari
SPSathishbabu Paranthaman
Sathishbabu Paranthaman
ALAmr Abu Lila
Amr Abu Lila
KAKhaled Almansour
Khaled Almansour
DGDevegowda Vishkante Gowda
Devegowda Vishkante Gowda
Denture stomatitis (DS), usually caused by Candida infection, is one of the common denture-related complications in patients wearing dentures. Clove and cinnamon oils have been acknowledged for their anti-inflammatory, antimicrobial activity, and antifungal effects in the oral cavity. The aim of this study, therefore, was to prepare clove/cinnamon oils-loaded emulgel and to assess its efficacy in treating Candida albicans-associated denture stomatitis. Central composite design was adopted to formulate and optimize clove/cinnamon extracts-loaded emulgel. The formulated preparations were assessed for their physical appearance, particle size, viscosity, spreadability, and in-vitro drug release. In addition, in-vivo therapeutic experiments were conducted on 42 patients with denture stomatitis. The prepared emulgel formulations showed good physical characteristics with efficient drug release within 3 h. In addition, in-vivo antifungal studies revealed that the optimized formula significantly (p < 0.001) reduced Candida colony counts from the denture surface, compared to commercially available gel (240.38 ± 27.20 vs. 398.19 ± 66.73 CFU/mL, respectively). Furthermore, the optimized formula and succeeded in alleviating denture stomatitis-related inflammation with a better clinical cure rate compared to commercially available gel Collectively, herbal extracts-loaded emulgel might be considered an evolution of polyherbal formulations and might represent a promising alternative to the existing allopathic drugs for the treatment of denture stomatitis, with better taste acceptability and no side effects.

24 July 2023 in Prosthesis
Verified
Journal Article
Open access
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NRNaveen Reddy
Naveen Reddy
SVSwetha Vempalli
Swetha Vempalli
JPJayant Prakash
Jayant Prakash
MSMAHESH SUGANNA
MAHESH SUGANNA
MSMeenakshi S
Meenakshi S
Giuseppe MinerviniGiuseppe Minervini
Giuseppe Minervini
Digital dentistry has gained significant attention in recent years due to its potential to improve the accuracy of implant placement and prosthesis fabrication. However, the literature on its effectiveness remains controversial, and a systematic review and meta-analysis are necessary to evaluate the available evidence. A comprehensive search was conducted across multiple online databases using MeSH keywords and Boolean operators. Data extraction was performed, and a bias assessment was conducted based on modified CONSORT guidelines. The pooled odds ratios (OR) and risk ratios (RR) and corresponding 95% confidence intervals (CI) were then calculated. Five studies met the inclusion criteria. The overall analysis showed no statistically significant difference in the accuracy of implant placement and prosthesis fabrication between digital and conventional techniques (OR: 0.95, 95% CI: 0.73 to 1.23 and RR: 0.95, 95% CI: 0.73 to 1.23). Subgroup analysis based on individual studies did not demonstrate consistent results. This review suggests that digital techniques do not significantly impact the accuracy of implant placement and prosthesis fabrication compared to conventional techniques in an in vitro setting. However, the overall evidence is limited by the small number of studies and the heterogeneity observed. Future well-designed studies, including randomized controlled trials and clinical studies, are needed to provide more robust evidence on the effectiveness of digital dentistry in clinical practice.

21 October 2021 in Journal of Pharmaceutical Research International
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Journal Article
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MSMeenakshi S
Meenakshi S
SDShyla Dureja
Shyla Dureja
GKG. C. Kavitha
G. C. Kavitha
MPM. Pallavi
M. Pallavi
KSK. N. Raghavendra Swamy
K. N. Raghavendra Swamy
RRRamith Ramu
Ramith Ramu
Gagging reflex poses a hurdle in numerous dental procedures. It causes discomfort for the patient, extended procedure time for the clinician, compromised quality of treatment and along with a lot of physiological discomfort for both. The normal gag reflex is protective in nature, but few individuals elicit extreme response, leading to problems during the treatment procedures. It is extremely important for the clinician to identify the cause and severity of the condition so that it can be decided whether the patient can handle standard treatment techniques or whether alternative methods must be considered. There is no universal solution for successfully managing the gagging patient. Various modalities can be used according to the doctor’s assessment and patient’s conditions in order to control the gag reflex so that the patient can be comfortable and cope with the dental treatment. A wide range of management solutions are available, and many cases need a combination of therapeutic procedures. The main aim of the present article is to comprehensively report the clinical significance, etiology, symptoms and various management approaches used during prosthodontic treatments.

1 October 2023 in International Journal of Health & Allied Sciences
Verified
Journal Article
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SBSparsh Bhat
Sparsh Bhat
SJSuresh Joghee
Suresh Joghee
MSMeenakshi S
Meenakshi S
Nelumbo nucifera generally known as ‘sacred lotus’ is a plant with high medicinal value in traditional medicine system especially in Chinese medicine system which is having a wide distribution worldwide in Asian, Western European, American and Australian continent. All the parts of the plant have different medicinal value, as their extract contains various valuable chemical constituents which yield desired remedial effects against many diseases. The plant is used traditionally more compared to its commercial usage. It has also been used for dental and skin care products in many herbal formulations. In this review, data about its general description, its distribution, chemical constituents and therapeutic effects has been provided. The plant has various uses against many diseases and the review focus on antiepileptic, anti-viral, anti-cancer, antimicrobial, anti-inflammatory, anti-hyperlipidemic, anthelmintic, anxiolytic & antidepressant, anti-cariogenic, analgesic, hepatoprotective, vasorelaxant, anti-coagulant, anti-obesity, anti-neurodegenerative, anti-aging, anti-oxidant, and immunomodulatory properties of the plant.

1 April 2022 in International Journal of Health & Allied Sciences
Verified
Journal Article
Open access
PDF file
ITIndu Thammaiah
Indu Thammaiah
MSMeenakshi S
Meenakshi S
NRNagasundara Rao Raghunath
Nagasundara Rao Raghunath
RRRamith Ramu
Ramith Ramu
Background: The speech of individuals with cleft lip and palate is primarily characterized by nasality of oral speech because of cleft and or velopharyngeal dysfunction. Objectives: The aim of the present study is to investigate the acoustical assessment and perceptual rating measurements in cleft lip and palate children. Methods: The study participants included 30 children with cleft lip and palate in the age range of 4—12 years. Prior parental consent was obtained for the inclusion of their children in the study. Speech analysis of all the l the participants were recorded. Prerecorded speech samples of the CLP groups were mixed randomized and played, using headphone in a quiet room. The speech-language pathologist (SLP) rated the nasality of the participant. Samples for perceptual evaluation are 15 phonation samples of/ă/,/I/and/ǔ/vowels vowel, 15 conversation samples and 30 subjects (3 oral sentences each so total 90 sentences). Results: For the Phonation sample, SLP must evaluate the presence of hypernasality by Wilcoksons nasality scale. Acoustic analysis was done using PRAAT software. The spectral and temporal parameters were measured. The Kappa coefficient was 0.88 for inter-rater reliability for nasality rating scale, 0.82 for speech intelligibility,1.02 for speech understandability,1.00 for speech acceptability, which suggests substantial agreement between the raters for four different rating scales. Conclusion: Hence both acoustical and perceptual evaluation play an important role in children with CLP.

1 April 2022 in International Journal of Health & Allied Sciences
Verified
Journal Article
Open access
PDF file
NUNaga Usha
Naga Usha
SRSwamy Kn. Raghavendra
Swamy Kn. Raghavendra
MSMeenakshi S
Meenakshi S
SGS. Ganesh
S. Ganesh
RRRamith Ramu
Ramith Ramu
Background: The main purpose of prosthetic rehabilitation is to enhance the masticatory function by replacing the missing teeth with an artificial substitute, which improves nutrient-rich food intake. There are recent studies which indicate the influence of chewing behavior and energy intake, but little is known about the relationship between chewing on nutritional status. Objective: This study intended to assess the changes in masticatory efficiency before and after prosthetic rehabilitation and its influence on nutritional status and body weight. Methods: A total of 40 partially edentulous subjects aged between 45 and 65 years were recruited. Body Mass Index was determined by measuring body weight using a medical grade weighing scale. Height was measured using wall mounted stature meter and Waist circumference was measured with an anthropometric measure tape. Masticatory efficiency was determined using the sieve method with peanuts as test food at baseline, at 3 and 6 months of prosthetic rehabilitation with a removable partial denture. Results: Sieve test performed for evaluating masticatory efficiency showed an increase in the percentage of smaller particles by 28.3% in non-obese and 32.15% in the obese group. The obese/overweight group showed a decrease in BMI values and non-obese subjects showed no significant change in BMI. Conclusion: The study concluded that improving masticatory efficiency by prosthodontic rehabilitation can aid in normalizing the nutritional status in certain partially edentulous non-obese and obese individuals.