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Despite monkeypox (mpox) being a public health emergency, there is limited knowledge about the risk of infectivity from skin viral loads during mpox infection. Thus, the aim of this study was to estimate cutaneous viral loads among mpox patients globally. Several databases, including Cochrane, EBSCOHost, EMBASE, ProQuest, PubMed, Scopus, and Web of Science, and preprint servers were searched concerning skin mpox viral loads in confirmed mpox subjects. In this systematic review and meta-analysis, a total of 331 articles were initially screened after the removal of duplicate entries. A total of nine articles were included in the systematic review and meta-analysis for the overall estimation of viral loads (Ct) using a random-effect model. The pooled cutaneous mpox viral load (lower Ct) was 21.71 (95% CI: 20.68–22.75) with a majority of positivity rates being 100%, highlighting a higher infectivity risk from skin lesions. The current results strongly support that skin mpox viral loads may be a dominant source of rapid transmission during current multi-national outbreaks. This important finding can help in constructing useful measures in relevant health policy.

BACKGROUND: Diabetes mellitus is one of the growing medical problems that affect people of all ages worldwide. Education is an important part of treatment in this chronic condition. The primary objectives of diabetes education include improving knowledge and skills, changing the patient’s behavior, motivating them to follow therapeutic recommendations, establishing self-care habits, and increasing their psychological resilience. The authors aimed to examine the effect of a training program on type 2 diabetic patients’ self care and investigate their perspectives on the educational program. MATERIALS AND METHODS: The current study used a quasi-experimental, pretest-posttest design that was conducted in Iraq. Sixty patients who met the selection criteria were included in the study. Data were collected by demographic questionnaire and the Diabetes Self-Care Scale (DSCS). Data analysis was done by independent T-tests and Paired t-tests were used to compare the scores before and after the intervention. RESULTS: The sample included 60 diabetic patients with more than half of them being female (55%). Most respondents aged between 50 and 60 years old, and next to half of them had only primary school education. We found that training programs can improve self-care behavior among diabetic patients so that following the intervention, the self-care score increased from 1.79 ± 0.360 to 3.17 ± 0.546 (P = 0.01). CONCLUSION: Since diabetes is a chronic condition that affects the whole individual’s life, self-care plays an important role in preventing potential complications and improving quality of life. Training programs, on the other hand, increase the awareness and knowledge of patients and enable them to handle this chronic condition properly.

To estimate the global burden of stillbirths among pregnant women with the COVID-19 vaccination. In this systematic review and meta-analysis, a literature search was carried out in PubMed, Cochrane and Scopus until February 4, 2023, with language restriction (English). Title-abstract screening followed by full text review was done independently by two authors, based on the research question, "What is the prevalence of stillbirths among the pregnant women vaccinated with COVID-19 vaccines?" Two authors independently extracted the relevant data from every study. The third author resolved the conflict. This study was registered in PROSPERO and followed the PRISMA guidelines. A Random effects model was applied to assess the pooled estimate of stillbirths. The I² test was used to assess the heterogeneity of the articles included in the study. For checking the publication bias, the Doi plot and the contour-enhanced funnel plot were utilized. The database systematic search yielded 168 articles; 11 of them were determined to be eligible for systematic review and 8 of them ended up being included for meta-analysis. The pooled prevalence of stillbirth in pregnant women vaccinated against COVID-19 infection was 0.00509 (5 per 1000 live births delivered by pregnant women vaccinated against COVID-19 (95% CI: 0.00003-0.01676). Statistically significant heterogeneity was reported across studies (I² = 98%; p < 0.01). The study concluded that vaccination against COVID-19 among pregnant women had a low stillbirth rate. It adds to the existing evidence that the COVID-19 vaccine is safe and can be taken during pregnancy.