A prerequisite for many quantum information processing tasks to truly surpass classical approaches is an efficient procedure to encode classical data in quantum superposition states. In this work, we present a circuit-based flip-flop quantum random access memory to construct a quantum database of classical information in a systematic and flexible way. For registering or updating classical data consisting of M entries, each represented by n bits, the method requires O(n) qubits and O(Mn) steps. With post-selection at an additional cost, our method can also store continuous data as probability amplitudes. As an example, we present a procedure to convert classical training data for a quantum supervised learning algorithm to a quantum state. Further improvements can be achieved by reducing the number of state preparation queries with the introduction of quantum forking.

A quantum error mitigation technique based on machine learning is proposed, which learns how to adjust the probabilities estimated by measurement in the computational basis. Neural networks in two different designs are trained with random quantum circuits consisting of a set of one- and two-qubit unitary gates whose measurement statistics in the ideal (noiseless) and real (noisy) cases are known. Once the neural networks are trained, they infer the amount of probability adjustment to be made on the measurement obtained from executing an unseen quantum circuit to reduce the error. The proposed schemes are tested with two-, three-, five-, and seven-qubit quantum circuits of depth up to 20 by computer simulations with realistic error models and experiments using the IBM quantum cloud platform. In all test cases, the proposed mitigation technique reduces the error effectively. Our method can be used to improve the accuracy of noisy intermediate-scale quantum (NISQ) algorithms without relying on extensive error characterization or quantum error correction.

Nonlinear distortion from a directly modulated laser (DML) is one of the major limiting factors to enhance the transmission capacity beyond 10 Gb/s for an intensity modulation direct-detection (IM/DD) optical access network. In this letter, we propose and demonstrate a low-complexity nonlinear equalizer (NLE) based on a machine-learning algorithm called artificial neural network (ANN). Experimental results for a DML-based 20 Gb/s signal transmission over an 18km SMF-28e fiber at 1310-nm employing pulse amplitude modulation (PAM)-4 confirm that the proposed ANN-NLE equalizer can increase the channel capacity and significantly reduce the impact of nonlinear penalties.

Quantum computers offer significant potential for complex system analysis, yet their application in large systems is hindered by limitations such as qubit availability and quantum hardware noise. While the variational quantum eigensolver (VQE) was proposed to address these issues, its scalability remains limited. Many efforts, including new ansätze and Hamiltonian modifications, have been made to overcome these challenges. In this work, we introduced the novel Fragment Molecular Orbital/Variational Quantum Eigensolver (FMO/VQE) algorithm. This method combines the fragment molecular orbital (FMO) approach with VQE and efficiently utilizes qubits for quantum chemistry simulations. Employing the UCCSD ansatz, the FMO/VQE achieved an absolute error of just 0.053 mHa with 8 qubits in a $${{\text{H}}}_{24}$$H 24 system using the STO-3G basis set, and an error of 1.376 mHa with 16 qubits in a $${{\text{H}}}_{20}$$H 20 system with the 6-31G basis set. These results indicated a significant advancement in scalability over conventional VQE, maintaining accuracy with fewer qubits. Therefore, our FMO/VQE method exemplifies how integrating fragment-based quantum chemistry with quantum algorithms can enhance scalability, facilitating more complex molecular simulations and aligning with quantum computing advancements.

A kernel-based quantum classifier is the most practical and influential quantum machine learning technique for the hyper-linear classification of complex data. We propose a Variational Quantum Approximate Support Vector Machine (VQASVM) algorithm that demonstrates empirical sub-quadratic run-time complexity with quantum operations feasible even in NISQ computers. We experimented our algorithm with toy example dataset on cloud-based NISQ machines as a proof of concept. We also numerically investigated its performance on the standard Iris flower and MNIST datasets to confirm the practicality and scalability.

Inspired by classical graph neural networks, we discuss a novel quantum graph neural network (QGNN) model to predict the chemical and physical properties of molecules and materials. QGNNs were investigated to predict the energy gap between the highest occupied and lowest unoccupied molecular orbitals of small organic molecules. The models utilize the equivariantly diagonalizable unitary quantum graph circuit (EDU-QGC) framework to allow discrete link features and minimize quantum circuit embedding. The results show QGNNs can achieve lower test loss compared to classical models if a similar number of trainable variables are used, and converge faster in training. This paper also provides a review of classical graph neural network models for materials research and various QGNNs.