To accurately identify the land ecological security in the middle and lower reaches of the Yangtze River, we measured the land ecological security based on the PSR model, selected a total of 19 indicators, such as population density, and applied the methods of system evaluation value conversion, comprehensive evaluation value and coordination degree measurement to study the land ecological security in the region. Research findings: The comprehensive evaluation level showed that Jiangxi, Shanghai, and Hunan had comprehensive evaluation values according to the regional forefront. The subsystem evaluation level showed that Shanghai and Hunan had higher pressure subsystem evaluation values relative to other provinces; Shanghai, Zhejiang, and Anhui had higher state subsystem evaluation values relative to other provinces; and Jiangxi was much more responsive to land ecological security issues than were other provinces and cities in the region. The system coordination degree showed that the comprehensive evaluation value of land ecological safety and the coordination degree evaluation value of other provinces except Shanghai and Hunan showed a negative correlation, indicating certain land ecological safety problems in the region. Finally, suggested reflections based on the conclusions are presented.