The development of aluminum anodization technology features many stages. With the story stretching for almost a century, rather straightforward—from current perspective—technology, raised into an iconic nanofabrication technique. The intrinsic properties of alumina porous structures constitute the vast utility in distinct fields. Nanoporous anodic alumina can be a starting point for: Templates, photonic structures, membranes, drug delivery platforms or nanoparticles, and more. Current state of the art would not be possible without decades of consecutive findings, during which, step by step, the technique was more understood. This review aims at providing an update regarding recent discoveries—improvements in the fabrication technology, a deeper understanding of the process, and a practical application of the material—providing a narrative supported with a proper background.
Controlled drug delivery systems are an encouraging solution to some drug disadvantages such as reduced solubility, deprived biodistribution, tissue damage, fast breakdown of the drug, cytotoxicity, or side effects. Self-ordered nanoporous anodic alumina is an auspicious material for drug delivery due to its biocompatibility, stability, and controllable pore geometry. Its use in drug delivery applications has been explored in several fields, including therapeutic devices for bone and dental tissue engineering, coronary stent implants, and carriers for transplanted cells. In this work, we have created and analyzed a stimuli-responsive drug delivery system based on layer-by-layer pH-responsive polyelectrolyte and nanoporous anodic alumina. The results demonstrate that it is possible to control the drug release using a polyelectrolyte multilayer coating that will act as a gate.
Multilayers consisting of the periodic repetition of two layers with different refractive indices ( and ) may have an omnidirectional band gap, the width of which depends on the incidence medium and on the refractive index ratio . In porous silicon, this ratio is limited by the material and fabrication characteristics. This article makes a theoretical study of two multilayer structures in order to enlarge the omnidirectional band gap with the same refractive index ratio by varying only the thickness of the period. These structures are named balanced and unbalanced mirrors and consist of a few periodic multilayers stacked together. Porous silicon balanced and unbalanced mirrors with enlarged omnidirectional band gap for applications are proposed. The results obtained with these mirror structures are compared with the results obtained with a chirped structure with the same characteristics.