Due to the limitations of current optical and sensor technologies and the high cost of updating them, the spectral and spatial resolution of satellites may not always meet desired requirements. For these reasons, Remote‐Sensing Single‐Image Super‐Resolution (RS‐SISR) techniques have gained significant interest. In this paper, Swin2‐MoSE model is proposed, an enhanced version of Swin2SR. The model introduces MoE‐SM, an enhanced Mixture‐of‐Experts (MoE) to replace the Feed‐Forward inside all Transformer block. MoE‐SM is designed with Smart‐Merger, and new layer for merging the output of individual experts, and with a new way to split the work between experts, defining a new per‐example strategy instead of the commonly used per‐token one. Furthermore, it is analyzed how positional encodings interact with each other, demonstrating that per‐channel bias and per‐head bias can positively cooperate. Finally, the authors propose to use a combination of Normalized‐Cross‐Correlation (NCC) and Structural Similarity Index Measure (SSIM) losses, to avoid typical MSE loss limitations. Experimental results demonstrate that Swin2‐MoSE outperforms any Swin derived models by up to 0.377–0.958 dB (PSNR) on task of , and resolution‐upscaling ( and OLI2MSI datasets). It also outperforms SOTA models by a good margin, proving to be competitive and with excellent potential, especially for complex tasks. Additionally, an analysis of computational costs is also performed. Finally, the efficacy of Swin2‐MoSE is shown, applying it to a semantic segmentation task (SeasoNet dataset). Code and pretrained are available on https://github.com/IMPLabUniPr/swin2‐mose/tree/official_code