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The aim of this study was to quantitatively assess the residual adhesive on orthodontic ceramic bracket-removed dental surface. In orthodontic process, ceramic bracket was repeated debonding physically, then the adhesive remained on the dental surface. The residual adhesive caused a lack of adhesive strength between dental and ceramic bracket. Since commonly used adhesive in orthodontics is translucent, residual adhesive is hard to be detected with conventional microscopes. Therefore, 1310 nm center wavelength swept-source OCT system based on laboratory customized image processing algorithm was used for the precise detection of residual adhesive on tooth surface. The algorithm separates residual adhesive from dental surface by comparing the height of adjacent B-scan images, while providing color-scaled images emphasizing the thickness information of residual adhesive. Finally, the acquired results were compared with microscopic and adhesive remnant index scoring gold standards, while the comparison confirmed the potential merits and the improvements of the proposed method over gold standards.
Yoonseok Kim; Gu-In Jung; Deokmin Jeon; Ruchire Wijesinghe; Daewoon Seong; Jaeyul Lee; Woo Do; Sung-Min Kwon; Jong Lee; Jun Hwang; Hyun Kim; Kyu-Bok Lee; Mansik Jeon; Jeehyun Kim. Non-Invasive Optical Coherence Tomography Data-Based Quantitative Algorithm for the Assessment of Residual Adhesive on Bracket-Removed Dental Surface. Sensors 2021, 21, 4670 .
AMA StyleYoonseok Kim, Gu-In Jung, Deokmin Jeon, Ruchire Wijesinghe, Daewoon Seong, Jaeyul Lee, Woo Do, Sung-Min Kwon, Jong Lee, Jun Hwang, Hyun Kim, Kyu-Bok Lee, Mansik Jeon, Jeehyun Kim. Non-Invasive Optical Coherence Tomography Data-Based Quantitative Algorithm for the Assessment of Residual Adhesive on Bracket-Removed Dental Surface. Sensors. 2021; 21 (14):4670.
Chicago/Turabian StyleYoonseok Kim; Gu-In Jung; Deokmin Jeon; Ruchire Wijesinghe; Daewoon Seong; Jaeyul Lee; Woo Do; Sung-Min Kwon; Jong Lee; Jun Hwang; Hyun Kim; Kyu-Bok Lee; Mansik Jeon; Jeehyun Kim. 2021. "Non-Invasive Optical Coherence Tomography Data-Based Quantitative Algorithm for the Assessment of Residual Adhesive on Bracket-Removed Dental Surface." Sensors 21, no. 14: 4670.
The successful surgery of chronic otitis media (COM) is challenging; this depends on the surgeon's knowledge of the optical visibility of surgical microscopes. Herein, we reported the utilization of intra-surgical optical coherence tomography (OCT) system to effectively guide the surgery of COM based on augmented reality with cross-sectional images. The intra-surgical spectral-domain OCT system with a center wavelength of 846 nm was capable of obtaining non-invasive, high-resolution, and high-speed visualizations with an axial resolution of 8 μm, lateral resolution of 30 μm, and an extended working distance of 280 mm. Three patients with COM were involved in this research. The lesion conditions of the temporal bone were observed with computed tomography pre-operatively. Furthermore, pure-tone audiogram examinations were performed to evaluate pre and post-surgical conditions. The results revealed that the averaged air-bone gap of 500 Hz, 1 kHz, 2 kHz, and 4 kHz in all cases improved to 61%. Thus, the research proves that the experimental procedure can be beneficial and clinically applicable with the developed intra-surgical OCT system for future otolaryngological assessments.
Hayoung Kim; Jaeyul Lee; Ruchire Eranga Wijesinghe; Jeong Hun Jang; Mansik Jeon; Jeehyun Kim. Intra-Operative Optical Coherence Imaging of In-Vivo Chronic Otitis Media Followed by Post-Operative Audiogram Assessments. IEEE Journal of Selected Topics in Quantum Electronics 2020, 27, 1 -7.
AMA StyleHayoung Kim, Jaeyul Lee, Ruchire Eranga Wijesinghe, Jeong Hun Jang, Mansik Jeon, Jeehyun Kim. Intra-Operative Optical Coherence Imaging of In-Vivo Chronic Otitis Media Followed by Post-Operative Audiogram Assessments. IEEE Journal of Selected Topics in Quantum Electronics. 2020; 27 (4):1-7.
Chicago/Turabian StyleHayoung Kim; Jaeyul Lee; Ruchire Eranga Wijesinghe; Jeong Hun Jang; Mansik Jeon; Jeehyun Kim. 2020. "Intra-Operative Optical Coherence Imaging of In-Vivo Chronic Otitis Media Followed by Post-Operative Audiogram Assessments." IEEE Journal of Selected Topics in Quantum Electronics 27, no. 4: 1-7.
Digital impressions have been studied for better gingival retraction in including the under subgingival finish line condition. Here, we employed swept-source optical coherence tomography (SS-OCT) of 1310 nm wavelength, which is capable of noninvasive, high-resolution, and high-speed, to discern the utilization-possibility for supporting the fabrication of the dental crown. A three-dimensional (3D) abutment was used at the 0.5 mm of the subgingival finish line below the level of the gingiva. The SS-OCT system scanned a field of view of 10 mm × 10 mm using the 3D working model by the depth-directional three focal points. The obtained 1500 images of OCT cross-sections, which are 1221 × 1220 pixels, were rendered to the 3D model for the effective design of a virtual crown. Then, the ceramic crown was fabricated through a milling machine with a computer-aided design and computer-aided manufacturing (CAD/CAM) software. The marginal fit of the crown was evaluated 219.1 ± 48.9 μm by a silicone replica technique. Although the marginal fit is not sufficient for the clinical allowable gap at one resin typodont, this study can be anticipated to encourage further researches for the enhanced fabrication of dental crown under subgingival finish line conditions.
Sangbong Lee; KeunBaDa Son; Jaeyul Lee; Mansik Jeon; Kyu-Bok Lee; Jeehyun Kim. Fabrication of Dental Crown by Optical Coherence Tomography: A Pilot Study. IEEE Access 2020, 8, 144969 -144975.
AMA StyleSangbong Lee, KeunBaDa Son, Jaeyul Lee, Mansik Jeon, Kyu-Bok Lee, Jeehyun Kim. Fabrication of Dental Crown by Optical Coherence Tomography: A Pilot Study. IEEE Access. 2020; 8 (99):144969-144975.
Chicago/Turabian StyleSangbong Lee; KeunBaDa Son; Jaeyul Lee; Mansik Jeon; Kyu-Bok Lee; Jeehyun Kim. 2020. "Fabrication of Dental Crown by Optical Coherence Tomography: A Pilot Study." IEEE Access 8, no. 99: 144969-144975.
The accurate screening of otitis media (OM) lies in clarifying the numerous confounding and quantitative factors that are discovered during primary inspections. Increased awareness about bacterial biofilms and inflammation has allowed researchers to develop a better understanding of the bacterial infections that occur in the middle ear. In this study, four live guinea pigs were inoculated with Streptococcus pneumonia to induce OM-related inflammatory changes. Since optical techniques have been effectively used for diagnosis in medicine, low-coherence interferometry-based optical coherence tomography (OCT) was employed for depth-resolved high-resolution data screening. Multiple locations of the tympanic membrane (TM), mastoid mucosa, and round window membrane were examined to assess inflammatory changes. We performed qualitative assessments and thickness quantifications and investigated the variations due to adverse inflammatory affects. The findings of the present study provide a better understanding of S. pneumonia bacteria caused inflammatory changes in middle ear and it further provides a fundamental platform for future clinical utility.
Ruchire Eranga Wijesinghe; Jaeyul Lee; Deokmin Jeon; Pil Un Kim; Sangyeob Han; Junsoo Lee; Daewoon Seong; Dong-Eun Lee; Jeong Hun Jang; Mansik Jeon; Jeehyun Kim. Non-Invasive Optical Screening of Streptococcus Pneumonia Based Inflammatory Changes of the Tympanic Membrane and Mastoid Mucosa in Guinea Pig Otitis Media Using Optical Coherence Tomography. IEEE Photonics Journal 2020, 12, 1 -11.
AMA StyleRuchire Eranga Wijesinghe, Jaeyul Lee, Deokmin Jeon, Pil Un Kim, Sangyeob Han, Junsoo Lee, Daewoon Seong, Dong-Eun Lee, Jeong Hun Jang, Mansik Jeon, Jeehyun Kim. Non-Invasive Optical Screening of Streptococcus Pneumonia Based Inflammatory Changes of the Tympanic Membrane and Mastoid Mucosa in Guinea Pig Otitis Media Using Optical Coherence Tomography. IEEE Photonics Journal. 2020; 12 (4):1-11.
Chicago/Turabian StyleRuchire Eranga Wijesinghe; Jaeyul Lee; Deokmin Jeon; Pil Un Kim; Sangyeob Han; Junsoo Lee; Daewoon Seong; Dong-Eun Lee; Jeong Hun Jang; Mansik Jeon; Jeehyun Kim. 2020. "Non-Invasive Optical Screening of Streptococcus Pneumonia Based Inflammatory Changes of the Tympanic Membrane and Mastoid Mucosa in Guinea Pig Otitis Media Using Optical Coherence Tomography." IEEE Photonics Journal 12, no. 4: 1-11.
Dental crowns are used to restore decayed or chipped teeth, where their surfaces play a key role in this restoration process, as they affect the fitting and stable bonding of the prostheses. The surface texture of crowns can interfere with this restoration process, therefore the measurement of their inner surface roughness is very important but difficult to achieve using conventional imaging methods. In this study, the inner surfaces of dental crowns were three-dimensionally (3D) visualized using swept-source optical coherence tomography (SS-OCT) system. Nine crowns were fabricated with a commercial 3D printer using three different hatching methods (one-way, cross, and 30° angle counter-clockwise) and three different build direction angles (0°, 45°, and 90°). In addition, an image processing algorithm was developed, which uses morphological filtering, boundary detection, and a high-pass frequency filtering technique, to quantitatively evaluate the inner surface roughness of the dental crowns cross-sections with the depth-of-focus set to match two different regions. The averaged smoothness of fabricated crown was effectively produced using the cross-hatching and the build direction angle of 90° by the respective process. Thus, the results confirm the potential use of this methodology to determine the best parameters to use in 3D fabrication for improving the effectiveness and stability of dental prostheses.
Jaeyul Lee; Sm Abu Saleah; Byeonggyu Jeon; Ruchire Eranga Wijesinghe; Dong-Eun Lee; Mansik Jeon; Jeehyun Kim. Assessment of the Inner Surface Roughness of 3D Printed Dental Crowns via Optical Coherence Tomography Using a Roughness Quantification Algorithm. IEEE Access 2020, 8, 133854 -133864.
AMA StyleJaeyul Lee, Sm Abu Saleah, Byeonggyu Jeon, Ruchire Eranga Wijesinghe, Dong-Eun Lee, Mansik Jeon, Jeehyun Kim. Assessment of the Inner Surface Roughness of 3D Printed Dental Crowns via Optical Coherence Tomography Using a Roughness Quantification Algorithm. IEEE Access. 2020; 8 (99):133854-133864.
Chicago/Turabian StyleJaeyul Lee; Sm Abu Saleah; Byeonggyu Jeon; Ruchire Eranga Wijesinghe; Dong-Eun Lee; Mansik Jeon; Jeehyun Kim. 2020. "Assessment of the Inner Surface Roughness of 3D Printed Dental Crowns via Optical Coherence Tomography Using a Roughness Quantification Algorithm." IEEE Access 8, no. 99: 133854-133864.
Optical fiber is widely used in optical coherence tomography (OCT) to propagate light precisely with low attenuation and low dispersion. However, the total optical path length within the optical fiber varies in accordance with changes of the temperature. This leads changes in the total optical travel path of the interfering signals and results in shifting of OCT image position to an unintended depth pixel value. In this paper, we presented the temperature-based automatic path length compensating method in OCT to limit the external temperature effect and control the image position in micro-scale without manual movement of optical components. By utilizing developed hardware and software of automatic temperature control system, the external temperature of optical fiber is precisely regulated that evokes thermal expansion and finally changes the physical length of fiber, which is main mechanism of temperature-based path length compensating method. The effectiveness of the presented method was verified by two-dimensional OCT images of mirror and in vivo retina. The obtained results confirmed the path length variance due to temperature change is computable and can be regulated in real-time for whole pixel range of OCT image. Therefore, the proposed temperature-based path length compensating method can be used as an alternative method to precisely control the position of OCT image, while eliminating the effect of external temperature and apply to effectively configuring compact optical systems.
Daewoon Seong; Sangyeob Han; Deokmin Jeon; Yoonseok Kim; Ruchire Eranga Wijesinghe; Naresh Kumar Ravichandran; Jaeyul Lee; Junsoo Lee; Pilun Kim; Dong-Eun Lee; Mansik Jeon; Jeehyun Kim. Dynamic Compensation of Path Length Difference in Optical Coherence Tomography by an Automatic Temperature Control System of Optical Fiber. IEEE Access 2020, 8, 77501 -77510.
AMA StyleDaewoon Seong, Sangyeob Han, Deokmin Jeon, Yoonseok Kim, Ruchire Eranga Wijesinghe, Naresh Kumar Ravichandran, Jaeyul Lee, Junsoo Lee, Pilun Kim, Dong-Eun Lee, Mansik Jeon, Jeehyun Kim. Dynamic Compensation of Path Length Difference in Optical Coherence Tomography by an Automatic Temperature Control System of Optical Fiber. IEEE Access. 2020; 8 (99):77501-77510.
Chicago/Turabian StyleDaewoon Seong; Sangyeob Han; Deokmin Jeon; Yoonseok Kim; Ruchire Eranga Wijesinghe; Naresh Kumar Ravichandran; Jaeyul Lee; Junsoo Lee; Pilun Kim; Dong-Eun Lee; Mansik Jeon; Jeehyun Kim. 2020. "Dynamic Compensation of Path Length Difference in Optical Coherence Tomography by an Automatic Temperature Control System of Optical Fiber." IEEE Access 8, no. 99: 77501-77510.
Depth-visualizing sensitivity can be degraded due to imperfect optical alignment and non-equidistant distribution of optical signals in the pixel array, which requires a measurement of the re-sampling process. To enhance this depth-visualizing sensitivity, reference and sample arm-channeled spectra corresponding to different depths using mirrors were obtained to calibrate the spectrum sampling prior to Fourier transformation. During the process, eight interferogram patterns corresponding to point spread function (PSF) signals at eight optical path length differences were acquired. To calibrate the spectrum, generated intensity points of the original interferogram were re-indexed towards a maximum intensity range, and these interferogram re-indexing points were employed to generate a new lookup table. The entire software-based process consists of eight consecutive steps. Experimental results revealed that the proposed method can achieve images with a high depth-visualizing sensitivity. Furthermore, the results validate the proposed method as a rapidly performable spectral calibration technique, and the real-time images acquired using our technique confirm the simplicity and applicability of the method to existing optical coherence tomography (OCT) systems. The sensitivity roll-off prior to the spectral calibration was measured as 28 dB and it was halved after the calibration process.
Sangyeob Han; Ruchire Eranga Wijesinghe; Deokmin Jeon; Youngmin Han; Jaeyul Lee; Junsoo Lee; Hosung Jo; Dong-Eun Lee; Mansik Jeon; Jeehyun Kim. Optical Interferometric Fringe Pattern-Incorporated Spectrum Calibration Technique for Enhanced Sensitivity of Spectral Domain Optical Coherence Tomography. Sensors 2020, 20, 2067 .
AMA StyleSangyeob Han, Ruchire Eranga Wijesinghe, Deokmin Jeon, Youngmin Han, Jaeyul Lee, Junsoo Lee, Hosung Jo, Dong-Eun Lee, Mansik Jeon, Jeehyun Kim. Optical Interferometric Fringe Pattern-Incorporated Spectrum Calibration Technique for Enhanced Sensitivity of Spectral Domain Optical Coherence Tomography. Sensors. 2020; 20 (7):2067.
Chicago/Turabian StyleSangyeob Han; Ruchire Eranga Wijesinghe; Deokmin Jeon; Youngmin Han; Jaeyul Lee; Junsoo Lee; Hosung Jo; Dong-Eun Lee; Mansik Jeon; Jeehyun Kim. 2020. "Optical Interferometric Fringe Pattern-Incorporated Spectrum Calibration Technique for Enhanced Sensitivity of Spectral Domain Optical Coherence Tomography." Sensors 20, no. 7: 2067.
Large field-of-view and fast scanning of photoacoustic microscopy relatively have been difficult to obtain due to the water-drowned structure of the system for the transmission of ultrasonic signals. It has been eagerly studied to achieve a waterproof scanner for dynamic biological applications with the high-resolution and high signal-to-noise ratio. This letter reports a novel waterproof galvanometer scanner-based photoacoustic microscopy system with successfully attainable 9.0 mm × 14.5 mm scan-region, amplitude-scan rate of 40 kHz, and spatial resolution of 4.9 μm. The in vivo characterization of mouse brain in intact-skull microvascular visualization demonstrated its capability in biomedical imaging and anticipating to be an effective technique for various preclinical and clinical studies.
Jaeyul Lee; Sangyeob Han; Daewoon Seong; Junsoo Lee; Sungjo Park; Ruchire Eranga Wijesinghe; Man Sik Jeon; Jeehyun Kim. Fully waterproof two-axis galvanometer scanner for enhanced wide-field optical-resolution photoacoustic microscopy. Optics Letters 2020, 45, 865 -868.
AMA StyleJaeyul Lee, Sangyeob Han, Daewoon Seong, Junsoo Lee, Sungjo Park, Ruchire Eranga Wijesinghe, Man Sik Jeon, Jeehyun Kim. Fully waterproof two-axis galvanometer scanner for enhanced wide-field optical-resolution photoacoustic microscopy. Optics Letters. 2020; 45 (4):865-868.
Chicago/Turabian StyleJaeyul Lee; Sangyeob Han; Daewoon Seong; Junsoo Lee; Sungjo Park; Ruchire Eranga Wijesinghe; Man Sik Jeon; Jeehyun Kim. 2020. "Fully waterproof two-axis galvanometer scanner for enhanced wide-field optical-resolution photoacoustic microscopy." Optics Letters 45, no. 4: 865-868.
Deokmin Jeon; Unsang Jung; Kibeom Park; Pilun Kim; Sangyeob Han; Hyosang Jeong; Ruchire Eranga Wijesinghe; Naresh Kumar Ravichandran; Jaeyul Lee; Youngmin Han; Mansik Jeon; Jeehyun Kim. Vision-Inspection-Synchronized Dual Optical Coherence Tomography for High-Resolution Real-Time Multidimensional Defect Tracking in Optical Thin Film Industry. IEEE Access 2020, 8, 190700 -190709.
AMA StyleDeokmin Jeon, Unsang Jung, Kibeom Park, Pilun Kim, Sangyeob Han, Hyosang Jeong, Ruchire Eranga Wijesinghe, Naresh Kumar Ravichandran, Jaeyul Lee, Youngmin Han, Mansik Jeon, Jeehyun Kim. Vision-Inspection-Synchronized Dual Optical Coherence Tomography for High-Resolution Real-Time Multidimensional Defect Tracking in Optical Thin Film Industry. IEEE Access. 2020; 8 ():190700-190709.
Chicago/Turabian StyleDeokmin Jeon; Unsang Jung; Kibeom Park; Pilun Kim; Sangyeob Han; Hyosang Jeong; Ruchire Eranga Wijesinghe; Naresh Kumar Ravichandran; Jaeyul Lee; Youngmin Han; Mansik Jeon; Jeehyun Kim. 2020. "Vision-Inspection-Synchronized Dual Optical Coherence Tomography for High-Resolution Real-Time Multidimensional Defect Tracking in Optical Thin Film Industry." IEEE Access 8, no. : 190700-190709.
Non-invasive characterization of micro-vibrations in the tympanic membrane (TM) excited by external sound waves is considered as a promising and essential diagnosis in modern otolaryngology. To verify the possibility of measuring and discriminating the vibrating pattern of TM, here we describe a micro-vibration measurement method of latex membrane resembling the TM. The measurements are obtained with an externally generated audio stimuli of 2.0, 2.2, 2.8, 3.1 and 3.2 kHz, and their respective vibrations based tomographic, volumetric and quantitative evaluations were acquired using optical Doppler tomography (ODT). The micro oscillations and structural changes which occurred due to diverse frequencies are measured with sufficient accuracy using a highly sensitive ODT system implied phase subtraction method. The obtained results demonstrated the capability of measuring and analyzing the complex varying micro-vibration of the membrane according to implied sound frequency.
Daewoon Seong; Jaehwan Kwon; Deokmin Jeon; Ruchire Eranga Wijesinghe; Jaeyul Lee; Naresh Kumar Ravichandran; Sangyeob Han; Junsoo Lee; Pilun Kim; Mansik Jeon; Jeehyun Kim. In Situ Characterization of Micro-Vibration in Natural Latex Membrane Resembling Tympanic Membrane Functionally Using Optical Doppler Tomography. Sensors 2019, 20, 64 .
AMA StyleDaewoon Seong, Jaehwan Kwon, Deokmin Jeon, Ruchire Eranga Wijesinghe, Jaeyul Lee, Naresh Kumar Ravichandran, Sangyeob Han, Junsoo Lee, Pilun Kim, Mansik Jeon, Jeehyun Kim. In Situ Characterization of Micro-Vibration in Natural Latex Membrane Resembling Tympanic Membrane Functionally Using Optical Doppler Tomography. Sensors. 2019; 20 (1):64.
Chicago/Turabian StyleDaewoon Seong; Jaehwan Kwon; Deokmin Jeon; Ruchire Eranga Wijesinghe; Jaeyul Lee; Naresh Kumar Ravichandran; Sangyeob Han; Junsoo Lee; Pilun Kim; Mansik Jeon; Jeehyun Kim. 2019. "In Situ Characterization of Micro-Vibration in Natural Latex Membrane Resembling Tympanic Membrane Functionally Using Optical Doppler Tomography." Sensors 20, no. 1: 64.
The geometrical characteristics of dental implants, such as thread depth and width, facing angle, pitch, and surface roughness, are important to assess their stability and osseointegration after implant surgery. Herein, we demonstrate the potential use of depth-resolved swept-source optical coherence tomography (SS-OCT) to assess the structural quality of widely used dental implants. The implemented SS-OCT system was centered at a wavelength of 1300 nm with a 100 nm full-width at half-maximum. Four dental implants with different structural formations fabricated using either titanium or ceramic were visualized. Qualitative assessments were performed using boundary flattening with an amplitude-profiling algorithm to emphasize and compare the thread depths, surface roughness, and inner structures of the experimental samples. Cross-sectional and volumetric OCT data clearly revealed the depth, width, and pitch of the dental implants, and especially, the quantitative assessment of axial and lateral thread depth unobtainable using conventional inspection methods was successfully conducted. The depth of thread was measured using a depth-directional intensity profile. In conclusion, the high-resolution SS-OCT system could be utilized to improve the quality assurance of dental implant products through multi-plane assessment.
Jaeyul Lee; Sangyeob Han; Junho Hwang; Sungjo Park; Deokmin Jeon; Kanghae Kim; Ruchire Eranga Wijesinghe; Kyu-Bok Lee; Mansik Jeon; Jeehyun Kim. Identification of multi-dimensional thread geometry using depth-resolved swept-source optical coherence tomography for assessment of dental implant fabrication. Optics and Lasers in Engineering 2019, 127, 105951 .
AMA StyleJaeyul Lee, Sangyeob Han, Junho Hwang, Sungjo Park, Deokmin Jeon, Kanghae Kim, Ruchire Eranga Wijesinghe, Kyu-Bok Lee, Mansik Jeon, Jeehyun Kim. Identification of multi-dimensional thread geometry using depth-resolved swept-source optical coherence tomography for assessment of dental implant fabrication. Optics and Lasers in Engineering. 2019; 127 ():105951.
Chicago/Turabian StyleJaeyul Lee; Sangyeob Han; Junho Hwang; Sungjo Park; Deokmin Jeon; Kanghae Kim; Ruchire Eranga Wijesinghe; Kyu-Bok Lee; Mansik Jeon; Jeehyun Kim. 2019. "Identification of multi-dimensional thread geometry using depth-resolved swept-source optical coherence tomography for assessment of dental implant fabrication." Optics and Lasers in Engineering 127, no. : 105951.
An elevated relative moisture in the external ear canal and middle ear cavity may predispose to chronic otorrhea and related infections along with abnormal tympanic membrane (TM) vibration patterns. Therefore, phase shift‐resolved optical Doppler vibrography (ODV) was used for vibration assessments of moisture influenced cadaveric TM. ODV was applied to generate time resolved cross‐sectional and volumetric vibrographs of a cadaveric TM, driven acoustically at several frequencies. In order to analyze the effect of moisture on TM, homogenous moisture conditions were provided by soaking the cadaveric TM specimens in 1X phosphate buffer saline with a pH of 7.4. The TM specimen was exposed to a rapidly switchable frequency generator during the ODV image acquisition. The experiment was conducted for 3 hours and the cadaveric TM was exposed to each frequency with an interval of 30 minutes. Acquired phase shift‐resolved ODV assessments revealed a depth dependent vibration tendency between the applied frequencies, along with a decline in the moisture level of the cadaveric TM specimen. Thus, the ODV method can aid our understanding of sound conduction in the middle ear, thus supporting the diagnosis of TM diseases. This article is protected by copyright. All rights reserved.
Byeonggyu Jeon; Jaeyul Lee; Deokmin Jeon; Pilun Kim; Jeong Hun Jang; Ruchire Eranga Wijesinghe; Mansik Jeon; Jeehyun Kim. Functional assessment of moisture influenced cadaveric tympanic membrane using phase shift‐resolved optical Doppler vibrography. Journal of Biophotonics 2019, 13, e201900202 .
AMA StyleByeonggyu Jeon, Jaeyul Lee, Deokmin Jeon, Pilun Kim, Jeong Hun Jang, Ruchire Eranga Wijesinghe, Mansik Jeon, Jeehyun Kim. Functional assessment of moisture influenced cadaveric tympanic membrane using phase shift‐resolved optical Doppler vibrography. Journal of Biophotonics. 2019; 13 (2):e201900202.
Chicago/Turabian StyleByeonggyu Jeon; Jaeyul Lee; Deokmin Jeon; Pilun Kim; Jeong Hun Jang; Ruchire Eranga Wijesinghe; Mansik Jeon; Jeehyun Kim. 2019. "Functional assessment of moisture influenced cadaveric tympanic membrane using phase shift‐resolved optical Doppler vibrography." Journal of Biophotonics 13, no. 2: e201900202.
Corneal transplantation by full‐thickness penetrating keratoplasty with human donor tissue is a widely accepted treatment for damaged or diseased corneas. Although corneal transplantation has a high success rate, a shortage of high‐quality donor tissue is a considerable limitation. Therefore, bioengineered corneas could be an effective solution for this limitation, and a decellularized extracellular matrix comprises a promising scaffold for their fabrication. In this study, three‐dimensional bioprinted decellularized collagen sheets were implanted into the stromal layer of the cornea of five rabbits. We performed in vivo noninvasive monitoring of the rabbit corneas using swept‐source optical coherence tomography (OCT) after implanting the collagen sheets. Anterior segment OCT images and averaged amplitude‐scans were acquired bi‐weekly to monitor corneal thickness after implantation for one month. The averaged cornea thickness in the control images was 430.3 ± 5.9 μm, while the averaged thickness after corneal implantation was 598.5 ± 11.8 μm and 564.5 ± 12.5 μm at two weeks and four weeks, respectively. The corneal thickness reduction of 34 μm confirmed the biocompatibility through the image analysis of the depth‐intensity profile base. Moreover, hematoxylin and eosin staining supported the biocompatibility evaluation of the bioprinted decellularized collagen sheet implantation. Hence, the developed bioprinted decellularized collagen sheets could become an alternative solution to human corneal donor tissue, and the proposed image analysis procedure could be beneficial to confirm the success of the surgery. This article is protected by copyright. All rights reserved.
Jaeseok Park; Kyoung‐Pil Lee; Hyeonji Kim; Sungjo Park; Ruchire Eranga Wijesinghe; Jaeyul Lee; Sangyeob Han; Sangbong Lee; Pilun Kim; Dong‐Woo Cho; Jinah Jang; Hong Kyun Kim; Mansik Jeon; Jeehyun Kim. Biocompatibility evaluation of bioprinted decellularized collagen sheet implanted in vivo cornea using swept‐source optical coherence tomography. Journal of Biophotonics 2019, 12, e201900098 .
AMA StyleJaeseok Park, Kyoung‐Pil Lee, Hyeonji Kim, Sungjo Park, Ruchire Eranga Wijesinghe, Jaeyul Lee, Sangyeob Han, Sangbong Lee, Pilun Kim, Dong‐Woo Cho, Jinah Jang, Hong Kyun Kim, Mansik Jeon, Jeehyun Kim. Biocompatibility evaluation of bioprinted decellularized collagen sheet implanted in vivo cornea using swept‐source optical coherence tomography. Journal of Biophotonics. 2019; 12 (11):e201900098.
Chicago/Turabian StyleJaeseok Park; Kyoung‐Pil Lee; Hyeonji Kim; Sungjo Park; Ruchire Eranga Wijesinghe; Jaeyul Lee; Sangyeob Han; Sangbong Lee; Pilun Kim; Dong‐Woo Cho; Jinah Jang; Hong Kyun Kim; Mansik Jeon; Jeehyun Kim. 2019. "Biocompatibility evaluation of bioprinted decellularized collagen sheet implanted in vivo cornea using swept‐source optical coherence tomography." Journal of Biophotonics 12, no. 11: e201900098.
In the past decade, there has been an increase in the development of sensitive, high-resolution, non-invasive diagnostic methods for periodontic diseases. Optical coherence tomography (OCT) has attracted considerable attention in clinical settings. In this study, a reliable, robust algorithm for the detection of gingival sulcus in 2D OCT cross-sectional images is proposed. Previously, the measurement of gingival sulcus in OCT images has been performed by manual identification using two-dimensional (2D) cross-sectional images. The automated detection of gingival sulcus continuity in 2D OCT images may help medical practitioners to assess important features of gingival tissues. The Sobel and canny operators have mainly been used for boundary and edge detection in OCT images. However, these algorithms are highly sensitive to noise and speckle in OCT images. To overcome these limitations, we propose an algorithm for the quantitative depth measurement of human gingival sulcus, based on averaged intensity difference. In this study, we utilized two commercially-available swept-source OCT systems operating at center wavelengths of 1310nm and 1060nm to image gingival sulcus of human samples in vivo. The images were processed using three algorithms: canny, Sobel and averaged intensity difference.
Naresh Kumar Ravichandran; Hoseong Cho; Jaeyul Lee; Sangyeob Han; Ruchire Eranga Wijesinghe; Pilun Kim; Jae-Won Song; Mansik Jeon; Jeehyun Kim. An Averaged Intensity Difference Detection Algorithm for Identification of Human Gingival Sulcus in Optical Coherence Tomography Images. IEEE Access 2019, 7, 73076 -73084.
AMA StyleNaresh Kumar Ravichandran, Hoseong Cho, Jaeyul Lee, Sangyeob Han, Ruchire Eranga Wijesinghe, Pilun Kim, Jae-Won Song, Mansik Jeon, Jeehyun Kim. An Averaged Intensity Difference Detection Algorithm for Identification of Human Gingival Sulcus in Optical Coherence Tomography Images. IEEE Access. 2019; 7 (99):73076-73084.
Chicago/Turabian StyleNaresh Kumar Ravichandran; Hoseong Cho; Jaeyul Lee; Sangyeob Han; Ruchire Eranga Wijesinghe; Pilun Kim; Jae-Won Song; Mansik Jeon; Jeehyun Kim. 2019. "An Averaged Intensity Difference Detection Algorithm for Identification of Human Gingival Sulcus in Optical Coherence Tomography Images." IEEE Access 7, no. 99: 73076-73084.
We demonstrated a preliminary research to investigate the feasible in vivo utilization of swept-source optical coherence tomography (SS-OCT) system with 1310 nm wavelength band to obtain morphological visualizations and human gingival sulcus depth measurements. Apart from the cross-sectional analysis, pixel intensity based OCT image classification algorithm is developed to identify the depth of gingival sulcus quantitatively. A total of 43 sites from the periodontal tissues of five healthy individuals were imaged in vivo by using the OCT system. Two periodontal tissues were right and left maxillary central incisors, while the other four periodontal tissues were left and right mandibular central incisors and later incisors. The developed classification algorithm could measure the gingival sulcus depths, which are 1.15±0.21 mm of the maxilla and 1.06±0.27 mm of the mandible. The averaged total depths obtained by the system was 1.10±0.26 mm. Hence, the gingival sulcus depth could be quantitatively measured by using the swept-source OCT system with the developed image classification algorithm as well as revealing a structural visualization, which ultimately confirmed the potential applicability for gingival sulcus depth real-time assessment.
Jaeyul Lee; Jaeseok Park; Muhammad Faizan Shirazi; Hosung Jo; Pilun Kim; Ruchire Eranga Wijesinghe; Mansik Jeon; Jeehyun Kim. Classification of human gingival sulcus using swept-source optical coherence tomography: In vivo imaging. Infrared Physics & Technology 2019, 98, 155 -160.
AMA StyleJaeyul Lee, Jaeseok Park, Muhammad Faizan Shirazi, Hosung Jo, Pilun Kim, Ruchire Eranga Wijesinghe, Mansik Jeon, Jeehyun Kim. Classification of human gingival sulcus using swept-source optical coherence tomography: In vivo imaging. Infrared Physics & Technology. 2019; 98 ():155-160.
Chicago/Turabian StyleJaeyul Lee; Jaeseok Park; Muhammad Faizan Shirazi; Hosung Jo; Pilun Kim; Ruchire Eranga Wijesinghe; Mansik Jeon; Jeehyun Kim. 2019. "Classification of human gingival sulcus using swept-source optical coherence tomography: In vivo imaging." Infrared Physics & Technology 98, no. : 155-160.
An internal and marginal fit between prosthesis and abutment is an important factor of the durability of dental prosthesis. In this paper, we have proposed the use of swept-source optical coherence tomography (OCT) as a novel application for non-ionized and high-resolution measurements of internal and marginal discrepancies at anatomically critical four points, such as occlusal, angle, axial, and margin during prosthesis attachment. A tooth model was fabricated by a 3D printing technique, and the dental prosthesis was designed using dental CAD software. The cross-sectional images along with intensity peak profile analysis of the sample were acquired using the OCT system for measurements of fit. The demonstrated qualitative and quantitative evaluations can be well-utilized for assessment of the internal and marginal fit of dental prosthesis.
Sangbong Lee; KeunBaDa Son; Jaeseok Park; Jaeyul Lee; Seok Hyon Kang; Ruchire Eranga Wijesinghe; Pilun Kim; Jun Ho Hwang; Sungjo Park; Byoung-Ju Yun; Mansik Jeon; Kyu-Bok Lee; Jeehyun Kim. Non-Ionized, High-Resolution Measurement of Internal and Marginal Discrepancies of Dental Prosthesis Using Optical Coherence Tomography. IEEE Access 2018, 7, 6209 -6218.
AMA StyleSangbong Lee, KeunBaDa Son, Jaeseok Park, Jaeyul Lee, Seok Hyon Kang, Ruchire Eranga Wijesinghe, Pilun Kim, Jun Ho Hwang, Sungjo Park, Byoung-Ju Yun, Mansik Jeon, Kyu-Bok Lee, Jeehyun Kim. Non-Ionized, High-Resolution Measurement of Internal and Marginal Discrepancies of Dental Prosthesis Using Optical Coherence Tomography. IEEE Access. 2018; 7 ():6209-6218.
Chicago/Turabian StyleSangbong Lee; KeunBaDa Son; Jaeseok Park; Jaeyul Lee; Seok Hyon Kang; Ruchire Eranga Wijesinghe; Pilun Kim; Jun Ho Hwang; Sungjo Park; Byoung-Ju Yun; Mansik Jeon; Kyu-Bok Lee; Jeehyun Kim. 2018. "Non-Ionized, High-Resolution Measurement of Internal and Marginal Discrepancies of Dental Prosthesis Using Optical Coherence Tomography." IEEE Access 7, no. : 6209-6218.
Significant technical and optical advances are required for intraoperative optical coherence tomography (OCT) to be utilized during otological surgeries. Integrating OCT with surgical microscopy makes it possible to evaluate soft tissue in real-time and at a high resolution. Herein, we describe an augmented-reality, intraoperative OCT/microscope system with an extended working distance of 280 mm, providing more space for surgical manipulation than conventional techniques. We initially performed ex vivo experiments to evaluate system performance. In addition, we validated the system by performing preliminary clinical assessments of tympanomastoidectomy outcomes in six patients with chronic otitis media. The system evaluated residual inflammation in the region-of-interest of the mastoid bone. Most importantly, the system intraoperatively revealed the connection between the graft and the remnant tympanic membrane. The extended working distance allows otological surgeons to evaluate the status of both the mastoid bone and tympanic membrane during manipulation, affording full intraoperative imaging.
Jaeyul Lee; Ruchire Eranga Wijesinghe; Deokmin Jeon; Pilun Kim; Yun-Hoon Choung; Jeong Hun Jang; Mansik Jeon; Jeehyun Kim. Clinical Utility of Intraoperative Tympanomastoidectomy Assessment Using a Surgical Microscope Integrated with an Optical Coherence Tomography. Scientific Reports 2018, 8, 1 -8.
AMA StyleJaeyul Lee, Ruchire Eranga Wijesinghe, Deokmin Jeon, Pilun Kim, Yun-Hoon Choung, Jeong Hun Jang, Mansik Jeon, Jeehyun Kim. Clinical Utility of Intraoperative Tympanomastoidectomy Assessment Using a Surgical Microscope Integrated with an Optical Coherence Tomography. Scientific Reports. 2018; 8 (1):1-8.
Chicago/Turabian StyleJaeyul Lee; Ruchire Eranga Wijesinghe; Deokmin Jeon; Pilun Kim; Yun-Hoon Choung; Jeong Hun Jang; Mansik Jeon; Jeehyun Kim. 2018. "Clinical Utility of Intraoperative Tympanomastoidectomy Assessment Using a Surgical Microscope Integrated with an Optical Coherence Tomography." Scientific Reports 8, no. 1: 1-8.
Kanghae Kim; Pilun Kim; Jaeyul Lee; Suwon Kim; Sungjo Park; Soo Ho Choi; Junho Hwang; Jong Hoon Lee; Ho Lee; Ruchire Eranga Wijesinghe; Mansik Jeon; Jeehyun Kim. Non-Destructive Identification of Weld-Boundary and Porosity Formation During Laser Transmission Welding by Using Optical Coherence Tomography. IEEE Access 2018, 6, 76768 -76775.
AMA StyleKanghae Kim, Pilun Kim, Jaeyul Lee, Suwon Kim, Sungjo Park, Soo Ho Choi, Junho Hwang, Jong Hoon Lee, Ho Lee, Ruchire Eranga Wijesinghe, Mansik Jeon, Jeehyun Kim. Non-Destructive Identification of Weld-Boundary and Porosity Formation During Laser Transmission Welding by Using Optical Coherence Tomography. IEEE Access. 2018; 6 ():76768-76775.
Chicago/Turabian StyleKanghae Kim; Pilun Kim; Jaeyul Lee; Suwon Kim; Sungjo Park; Soo Ho Choi; Junho Hwang; Jong Hoon Lee; Ho Lee; Ruchire Eranga Wijesinghe; Mansik Jeon; Jeehyun Kim. 2018. "Non-Destructive Identification of Weld-Boundary and Porosity Formation During Laser Transmission Welding by Using Optical Coherence Tomography." IEEE Access 6, no. : 76768-76775.
The precise identification of intra-cochlear microstructures is an essential otorhinolaryngological requirement to diagnose the progression of cochlea related diseases. Thus, we demonstrated an experimental procedure to investigate the most optimal wavelength range, which can enhance the visualization of ex vivo intra-cochlear microstructures using multiple wavelengths (i.e., 860 nm, 1060 nm, and 1300 nm) based optical coherence tomography (OCT) systems. The high-resolution tomograms, volumetric, and quantitative evaluations obtained from Basilar membrane, organ of Corti, and scala vestibule regions revealed complementary comparisons between the aforementioned three distinct wavelengths based OCT systems. Compared to 860 nm and 1300 nm wavelengths, 1060 nm wavelength OCT was discovered to be an appropriate wavelength range verifying the simultaneously obtainable high-resolution and reasonable depth range visualization of intra-cochlear microstructures. Therefore, the implementation of 1060 nm OCT can minimize the necessity of two distinct OCT systems. Moreover, the results suggest that the performed qualitative and quantitative analysis procedure can be used as a powerful tool to explore further anatomical structures of the cochlea for future studies in otorhinolaryngology.
Sungwook Kim; Ruchire Eranga Wijesinghe; Jaeyul Lee; Muhammad Faizan Shirazi; Pilun Kim; Jeong Hun Jang; Mansik Jeon; Jeehyun Kim. Multiple Wavelength Optical Coherence Tomography Assessments for Enhanced Ex Vivo Intra-Cochlear Microstructural Visualization. Electronics 2018, 7, 133 .
AMA StyleSungwook Kim, Ruchire Eranga Wijesinghe, Jaeyul Lee, Muhammad Faizan Shirazi, Pilun Kim, Jeong Hun Jang, Mansik Jeon, Jeehyun Kim. Multiple Wavelength Optical Coherence Tomography Assessments for Enhanced Ex Vivo Intra-Cochlear Microstructural Visualization. Electronics. 2018; 7 (8):133.
Chicago/Turabian StyleSungwook Kim; Ruchire Eranga Wijesinghe; Jaeyul Lee; Muhammad Faizan Shirazi; Pilun Kim; Jeong Hun Jang; Mansik Jeon; Jeehyun Kim. 2018. "Multiple Wavelength Optical Coherence Tomography Assessments for Enhanced Ex Vivo Intra-Cochlear Microstructural Visualization." Electronics 7, no. 8: 133.
The sciatic nerve is the longest and widest single nerve in the human body and is responsible for the signal transduction of the entire hind limb region. Its wide nerve dynamic range and size makes it sensitive to injury. The branching and location of the sciatic nerve are important, and unlike histology, optical coherence tomography (OCT) can provide rapid non-destructive cross-sectional images. The sciatic nerves of 10 rats were analyzed using swept-source (SS)-OCT. The sufficient depth penetration of the SS-OCT system allowed clear identification of the internal bifurcation point of the external branching and the internal route for the three terminal nerves in cross-sectional images. Internal bifurcation is observed through interfascicular epineurium resulting from epineurium division. Two bifurcations occur at the bottom of the sciatic nerve. The first and second bifurcations occur approximately 7 and 5 mm, respectively, above the external branching. SS-OCT enabled visualization of surgical needle positioning during direct injections into the sciatic nerve, which is beneficial for drug injection or microelectrode placement for electrical signal processing as a nerve detection guide. Therefore, analysis of the internal structure obtained in real time and needle position information inside the nerve are expected to act as a guide for neurosurgery.
Daeyoung Choi; Jaeyul Lee; Mansik Jeon; Jeehyun Kim. In Vivo Fascicle Bifurcation Imaging of Rat Sciatic Nerve Using Swept-Source Optical Coherence Tomography. IEEE Access 2018, 6, 7713 -7718.
AMA StyleDaeyoung Choi, Jaeyul Lee, Mansik Jeon, Jeehyun Kim. In Vivo Fascicle Bifurcation Imaging of Rat Sciatic Nerve Using Swept-Source Optical Coherence Tomography. IEEE Access. 2018; 6 ():7713-7718.
Chicago/Turabian StyleDaeyoung Choi; Jaeyul Lee; Mansik Jeon; Jeehyun Kim. 2018. "In Vivo Fascicle Bifurcation Imaging of Rat Sciatic Nerve Using Swept-Source Optical Coherence Tomography." IEEE Access 6, no. : 7713-7718.