The article describes the definition of a joint Master degree program for designers, focused on integrated skills to address the complexity of the future and to contribute to the green and digital transition of the European industrial context. Based on the application framework of the INTRIDE European project, the article presents an analysis of designers’ skills and the needs of European companies. The reflection then extends to the research methodology adopted, developing a state of the art on the European training offer on soft, digital, green skills, useful for the design of the interdisciplinary joint Master degree program. Based on the research results, authors propose the INTRIDE output as an innovative training course with integrated key competencies for designers, enhancing them as innovation triggers for SMEs in the manufacturing sector. Lastly, authors will discuss the design process carried out and will suggest a sustainable implementation of the training program designed.