Objective: Long‐term effectiveness is a critical aspect of the clinical utility of a treatment; however, a meta‐analytic evaluation of psychological and medical treatments for binge‐eating disorder (BED), including weight loss treatments, is outstanding. This meta‐analysis sought to provide a comprehensive evaluation of the long‐term effectiveness in diverse treatments for BED regarding a range of clinically relevant outcomes.Method: Based on a systematic search up to February 2018, 114 published and unpublished randomized‐controlled (RCTs), nonrandomized, and uncontrolled treatment studies, totaling 8,862 individuals with BED (DSM‐IV, DSM‐5), were identified and analyzed using within‐group random‐effect modeling.Results: Effectiveness (regarding binge‐eating episodes and abstinence, eating disorder and general psychopathology) up to 12 months following treatment was demonstrated for psychotherapy, structured self‐help treatment, and combined treatment, while the results regarding body weight reduction were inconsistent. These results were confirmed in sensitivity analyses with RCTs on the most common treatments—cognitive‐behavioral therapy and self‐help treatment based on this approach. Follow‐up intervals longer than 12 months were rarely reported, mostly supporting the long‐term effectiveness of psychotherapy. Few follow‐up data were available for pharmacotherapy, and behavioral and self‐help weight loss treatment, while follow‐up data were lacking for pharmacological and surgical weight loss treatment. Study quality varied widely.Discussion: This comprehensive meta‐analysis demonstrated the medium‐term effectiveness of psychotherapy, structured self‐help treatment, and combined treatment for patients with BED, and supported the long‐term effectiveness of psychotherapy. The results were derived from uncontrolled comparisons over time. Further long‐term high quality research on psychological and medical treatments for BED is required.

Over the last decade, fertility‐related issues have come to the fore of clinical oncology. The majority of research though has focused on a medical perspective without considering reproductive motivations that influence decisions on fertility‐preserving options. In order to identify specific parenthood motivations in young survivors of various types of cancer, a systematic review of the literature was conducted. Relevant literature was searched manually and using databases (Medline/PubMed, PsycInfo). Of 4848 articles retrieved, 20 studies met a priori defined inclusion criteria. Cancer was found to have a likely effect on reproductive intentions. All studies reported on specific reproductive concerns, mostly related to negative consequences for the patient or on the future child. Pregnancy concerns were overrepresented in breast cancer survivors. Practical barriers to post‐cancer parenthood were financial or partner‐referred. Overall, fewer incentives than disincentives for post‐cancer parenthood were reported. They included the importance of parenthood, achieving normality and a desire to focus on the positive. As reproductive motivations and concerns affect the majority of cancer survivors of reproductive age, they should be assessed as early as possible post‐diagnosis. While researchers should focus on the development of appropriate assessment methods, clinicians might address specific reproductive concerns.

This study aimed to investigate food addiction (FA) and binge-eating disorder (BED) in their association to executive dysfunctions in adults with obesity. Data on response inhibition, attention, decision-making, and impulsivity were derived from four groups of adults with obesity: obesity and FA (n = 23), obesity and BED (n = 19), obesity and FA plus BED (FA/BED, n = 23), and a body mass index-, age-, and sex-stratified control group of otherwise healthy individuals with obesity (n = 23, OB), using established computerized neuropsychological tasks. Overall, there were few group differences in neuropsychological profiles. Individuals of the FA group did not differ from the OB group regarding executive functioning. Individuals with BED presented with significantly higher variability in their reaction times and a deficient processing of feedback for performance improvement compared to individuals of the OB group. Strikingly, individuals with FA/BED did not present neuropsychological impairments, but higher levels of depression than all other groups. The results indicated the presence of a BED-specific neuropsychological profile in the obesity spectrum. The additional trait FA was not related to altered executive functioning compared to the OB or BED groups. Future research is needed to discriminate FA and BED further using food-specific tasks.