Yara Skaff

Dr. Yara Skaff

Internal Medicine, Hôpital Louis-Mourier, Colombes, Île-de-France, France
orcid

Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
YSYara Skaff
Yara Skaff
MJMohammad Jarrah
Mohammad Jarrah
RNRabih Nasrallah
Rabih Nasrallah
RHReina Habib
Reina Habib
RSRania Sakr
Rania Sakr
Background: Disaster disrupts the normal functioning of a community, causing significant damages and losses. In recent years, Lebanon faced multiple disasters, including one of the largest explosions ever recorded, the Beirut Blast, in August 2020. Limited studies in the literature have examined disaster medicine preparedness among healthcare professionals (HCPs). Objective: To examine the knowledge (K), attitude (A), readiness to practice (rP), and KArP associated with disaster medicine preparedness among HCPs in Lebanon. Methods: A cross-sectional observational study was conducted in Lebanon using data from participants answering an online survey. Participants enrolled in this study were HCPs (residents and faculty), medical students, and postdoctoral research scholars. Levels of knowledge, attitude, and readiness to practice were assessed and used to examine their association with participants’ socio-demographic characteristics. Results: A total of 195 participants (average age 30.6 ± 11.4 years) were included in this study. Participants reported moderate scores of knowledge, attitude, and readiness to practice. Older participants reported better readiness to practice and a KArP score. A significant difference was observed in all categories according to gender, with men having higher scores than women. No significant difference was observed between the level of education and knowledge, attitude, and total KArP scores. Conclusions: Our study’s findings showed that age and the level of education were positively correlated with readiness to practice. Men, compared to women, had significantly higher scores in all categories. Barriers to the KArP should be identified and targeted in future studies, as disaster preparedness at the institutional level may improve outcomes in future disaster encounters.

2 June 2023 in Cancers
Verified
Journal Article
Open access
PDF file
HHHélène Helfer
Hélène Helfer
YSYara Skaff
Yara Skaff
FHFlorent Happe
Florent Happe
SDSadji Djennaoui
Sadji Djennaoui
JCJean Chidiac
Jean Chidiac
Isabelle MahéIsabelle Mahé
Isabelle Mahé
Venous thromboembolic disease (VTE) is a common complication in cancer patients. The currently recommended VTE diagnostic approach involves a step-by-step algorithm, which is based on the assessment of clinical probability, D-dimer measurement, and/or diagnostic imaging. While this diagnostic strategy is well validated and efficient in the noncancer population, its use in cancer patients is less satisfactory. Cancer patients often present nonspecific VTE symptoms resulting in less discriminatory power of the proposed clinical prediction rules. Furthermore, D-dimer levels are often increased because of a hypercoagulable state associated with the tumor process. Consequently, the vast majority of patients require imaging tests. In order to improve VTE exclusion in cancer patients, several approaches have been developed. The first approach consists of ordering imaging tests to all patients, despite overexposing a population known to have mostly multiple comorbidities to radiations and contrast products. The second approach consists of new diagnostic algorithms based on clinical probability assessment with different D-dimer thresholds, e.g., the YEARS algorithm, which shows promise in improving the diagnosis of PE in cancer patients. The third approach uses an adjusted D-dimer threshold, to age, pretest probability, clinical criteria, or other criteria. These different diagnostic strategies have not been compared head-to-head. In conclusion, despite having several proposed diagnostic approaches to diagnose VTE in cancer patients, we still lack a dedicated diagnostic algorithm specific for this population.

16 January 2025 in European Journal of Clinical Investigation
Verified
Journal Article
Open access
Isabelle MahéIsabelle Mahé
Isabelle Mahé
YSYara Skaff
Yara Skaff
HHHélène Helfer
Hélène Helfer
SBSamuel Benarroch
Samuel Benarroch
FHFlorent Happe
Florent Happe
KANKOE SALLAHKANKOE SALLAH
KANKOE SALLAH
Background: Venous thromboembolism (VTE), including pulmonary embolism (PE) and deep vein thrombosis (DVT), is a potentially fatal disease with a multifactorial nature, impacting different medical and surgical specialties. Recently, new guidelines and direct oral anticoagulants facilitated early discharge for most DVT patients and non‐severe PE patients.Objective: The aim of this study is to illustrate the distribution of VTE patients throughout the hospital and map their care pathway from Emergency Department (ED) to hospital discharge.Methods: This multicenter retrospective cross‐sectional study included all hospitalized patients with a VTE code from 39 hospitals between 2018 and 2019. Data were analysed using JupyterLab, with subgroup analyses based on mode of entry, diagnosis location and thrombosis site.Results: A total of 23,199 hospitalizations were analysed, involving 17,718 patients a median age 66 years [52–78] and man‐to‐women ratio 1.05. Among these, 10,747(46.3%) had PE and 4176(18.0%) had lower limb DVT. The ED was the primary entry point for 31.2% of cases, followed by gastroenterology, surgery, geriatrics, and internal medicine. Patients admitted through ED patients were most frequently transferred to internal medicine, cardiovascular and intensive care units (ICU). The median hospital stay was 9 days [4–21], with ICU stays being the longest (mean 15 days [8–27]). Notably, 1357 patients (18.8%) of VTE patients were discharged within 48 h of ED admission.Conclusions: This study is the first to portray the distribution and care pathways of VTE patients across hospital departments. Despite recent clinical guidelines, many patients still require inpatient management, highlighting the need for dedicated care pathway.

16 January 2023 in Respiratory Medicine Case Reports
Verified
Journal Article
Open access
YSYara Skaff
Yara Skaff
MJMohammad Jarrah
Mohammad Jarrah
AFAndreas Filippaios
Andreas Filippaios
MSMusa A. Sharkawi
Musa A. Sharkawi
JMJordy Mehawej
Jordy Mehawej
Emphysematous pancreatitis is a severe systemic inflammatory process with reports of pulmonary embolism in the setting of acute pancreatitis rarely described. A 61-year-old woman presented with severe abdominal pain of 1 day duration. She was found to have acute interstitial pancreatitis. During her hospitalization, the patient developed worsening abdominal pain associated with increasing oxygen demands, requiring supplemental oxygen through nasal cannula. Workup showed pulmonary embolism in the posterior segmental branch of the left lower lobar artery and development of emphysematous pancreatitis was noted on imaging. The patient was started on intravenous antibiotics and therapeutic anticoagulation; her condition improved and was discharged home. Patients with severe acute pancreatitis may be at risk for pulmonary embolism due to immobilization and other inflammatory mechanisms. Mitigating individualized risk factors and anticoagulation use as prophylaxis should be considered in patients with pancreatitis to prevent embolism. Early detection by clinicians is critical to reduce misdiagnosis and mortality rates.

15 April 2025 in Vascular Diseases
Verified
Journal Article
Closed access
YSYara Skaff
Yara Skaff
AMAnnaig Miossec
Annaig Miossec
ARAlizée Raimbeau
Alizée Raimbeau
FDFrédéric Douane
Frédéric Douane
MMMarie Morard
Marie Morard
OEOlivier Espitia
Olivier Espitia