Biomass waste comes from a wide range of sources, such as forest, agricultural, algae wastes, as well as other relevant industrial by-products. It is an important alternative energy source as well as a unique source for various bioproducts applied in many fields. For the past two decades, how to reuse, recycle and best recover various biomass wastes for high value-added bioproducts has received significant attention, which has not only come from various academia communities but also from many civil and medical industries. To summarize one of the cutting-edge technologies applied with nanocellulose biomaterials, this review focused on various preparation methods and strategies to make nanocellulose from diverse biomass wastes and their potential applications in biomedical areas and other promising new fields.

Cellulose nanocrystals (CNCs) as a renewable and biodegradable nanomaterial have wide application value. In this work, CNCs were extracted from bleached chemical pulp using two stages of isolation (i.e. formic acid (FA) hydrolysis and 2,2,6,6-tetramethyl-piperidine-1-oxyl (TEMPO) mediated oxidation) under mild conditions. In the first stage, FA was used to remove hemicellulose, swell cellulose fibers, and release CNCs. The FA could be readily recovered and reused. In the second stage, the CNCs isolated by FA were further modified by TEMPO-mediated oxidation to increase the surface charge of CNCs. It was found that the modified CNCs with more ordered crystal structure and higher surface charge had better redispersibility and higher viscosity in aqueous phase. Therefore, the modified CNCs could be more effective when used as rheology modifier in the fields of water based coating, paint, food etc.