The union of aquaculture and hydroponics is named aquaponics—a system where microorganisms, fish and plants coexist in a water environment. Bacteria are essential in processes which are fundamental for the functioning and equilibrium of aquaponic systems. Such processes are nitrification, extraction of various macro- and micronutrients from the feed leftovers and feces, etc. However, in aquaponics there are not only beneficial, but also potentially hazardous microorganisms of fish, human, and plant origin. It is important to establish the presence of human pathogens, their way of entering the aforementioned systems, and their control in order to assess the risk to human health when consuming plants and fish grown in aquaponics. Literature analysis shows that aquaponic bacteria and yeasts are mainly pathogenic to fish and humans but rarely to plants, while most of the molds are pathogenic to humans, plants, and fish. Since the various human pathogenic bacteria and fungi found in aquaponics enter the water when proper hygiene practices are not applied and followed, if these requirements are met, aquaponic systems are a good choice for growing healthy fish and plants safe for human consumption. However, many of the aquaponic pathogens are listed in the WHO list of drug-resistant bacteria for which new antibiotics are urgently needed, making disease control by antibiotics a real challenge. Because pathogen control by conventional physical methods, chemical methods, and antibiotic treatment is potentially harmful to humans, fish, plants, and beneficial microorganisms, a biological control with antagonistic microorganisms, phytotherapy, bacteriophage therapy, and nanomedicine are potential alternatives to these methods.

The limited availability of water resources worldwide presents obstacles, to the progress of ag-riculture. This situation calls for the implementation of water saving technologies to address these challenges effectively. The quest for technologies that conserve water in agriculture, par-ticularly within the context of cotton production, is related to the study of the impact of drought on the growth, leaf surface area, accumulation of dry matter, boll number, and productivity. The benefits of local drip irrigation have been established. Various models and strategies for opti-mizing and improving the efficiency of how we use water for irrigation purposes. In a market driven economy the effective utilization of water assetsis closely linked to the improvement of managing mineral nutrients. To enhance both the quantity and quality of production, nitrogen is the key factor element that plays a role in the process. The formation of highly efficient cotton crops by adapting the growing technology to the specific soil-climatic conditions of the area, in-cluding controlling nitrogen fertilizing and irrigation, is the primary method to achieve con-sistent harvests. The results of irrigation with water deficit and feeding plants with different fer-tilizer rates are presented. This matter is presently significant, in achieving dependable crop harvests supporting the economic growth of farms and safeguarding the well being of agricul-tural environments.

The present research aims at assessing the influence of leaf fertilizers on the two common wheat varieties. Study results show that the crude protein content ranges from 128.50-143.94 g/kg DM in the Enola variety and from 115.93 to 127.34 g/kg DM in the Illico variety. The introduction of Wuxal Grano slurry increased the crude protein content by 9.1 and 12.0 % relative to the control. The applied leaf fertilizers do not affect the contents of FUM, FUG and PDI. As a result of the correlation analysis, a very high correlation (r = 0.947-0.993) was found between CP and PDI for both common wheat varieties.