Ira Holla

Dr. Ira Holla


Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Verified
Journal Article
Open access
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NDNilesh Dankhara
Nilesh Dankhara
IHIra Holla
Ira Holla
SRSumana Ramarao
Sumana Ramarao
RTRenjithkumar Kalikkot Kalikkot Thekkeveedu
Renjithkumar Kalikkot Kalikkot Thekkeveedu
Bronchopulmonary dysplasia (BPD), also known as chronic lung disease, is the most common respiratory morbidity in preterm infants. “Old” or “classic” BPD, as per the original description, is less common now. “New BPD”, which presents with distinct clinical and pathological features, is more frequently observed in the current era of advanced neonatal care, where extremely premature infants are surviving because of medical advancements. The pathogenesis of BPD is complex and multifactorial and involves both genetic and environmental factors. This review provides an overview of the pathology of BPD and discusses the influence of several prenatal and postnatal factors on its pathogenesis, such as maternal factors, genetic susceptibility, ventilator-associated lung injury, oxygen toxicity, sepsis, patent ductus arteriosus (PDA), and nutritional deficiencies. This in-depth review draws on existing literature to explore these factors and their potential contribution to the development of BPD.

13 September 2022 in Clinical Pediatrics
Verified
Journal Article
Closed access
AMAshley Markowski
Ashley Markowski
IHIra Holla
Ira Holla
MPMary Elaine Patrinos
Mary Elaine Patrinos

12 June 2025 in Children
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Journal Article
Open access
PDF file
IHIra Holla
Ira Holla
PAPradeep Alur
Pradeep Alur
As the limit of viability is extended to lower gestational ages, neonatologists caring for preterm infants must discover the optimal nutritional combination to support postnatal growth. It has been well established that introducing protein soon after birth is associated with improved short-term growth at 36 weeks postmenstrual age and neurodevelopment. However, it remains unclear what the optimal level of protein is for parenteral nutrition at various gestational ages. Several studies have shown possible adverse effects of high-protein delivery in very low birth weight infants. Inborn errors in amino acid metabolism also caution us that higher levels of specific amino acids can harm the growing brain.