Contrary to carbohydrate and fat metabolism, the influence of a single exercise dose on protein metabolism has not been adequately explored yet. We assessed the effects of different exercise intensities and durations on blood protein changes and their association with carbohydrate (CHO) and fat metabolism in six eligible trained subjects. Subjects performed maximal incremental (IE₁₀₀: at 100%VO_2max) and submaximal continuous exercise (CE) at 75%VO_2max for 30 min (CE₇₅) and at 50%VO_2max for 90 min (CE₅₀). Blood samples were collected at rest (R), end of exercise (EE), and 1 h after recovery to assess blood urea nitrogen (BUN), plasma amino acids (AA), glucose, lactate, FFA, and glycerol. In IE₁₀₀ blood lactate, CHO-oxidation (g/min), energy expenditure (kcal/min), and RER were significantly increased during rest (p < 0.05). CE₅₀ induced significantly higher BUN, FFA, glycerol, and fat oxidation (g/min) (p < 0.05). At recovery, the mean sum of the free AA pool (µmol/L) reduced by 8% (p < 0.03) during CE₅₀. Values for CE₇₅ were between IE₁₀₀ and CE₅₀. Beside lipolysis, also proteolysis (BUN) was an important source of fuel for low-to-moderate intensity CE₅₀. An increased uptake of AA from the plasma bed during CE₅₀ suggests the importance for oxidation and synthesis of other metabolic sources such as gluconeogenesis necessary for recovery. Therefore, one needs to be cautious of protein diet following prolonged cycle exercise training.

Background: anemia is becoming a public health problem particularly among people suffering from different types of cancer. Objective: the aim of this study was to assess the prevalence and associated factors of anemia among people with cancer. Methods: an institution based cross-sectional study was conducted from January to June 2020 in ACSH, Tigray, Ethiopia. Medical records were systematically reviewed to get demographic and clinical characteristics of 72 study subjects. Data were entered to SPSSv25 and descriptive analysis, logistic regression, independent sample T test and ANOVA were used for analysis. Results: about 45.8% of study subjects with different types of cancer were found to have anemia. Unemployment (OR=2.167; 95%CI: 1.093, 4.294; p=0.027), rural residence (OR = 3.750; 95%CI: 1.245, 11.299; p= 0.019), advanced stages of cancer (OR = 10.771; 95%CI: 3.580, 32.405; p= 0.000), duration of cancer (OR=3.542; 95%CI: 1.289, 9.728; p=0.014) and higher (5-8) cycles of chemotherapy (OR = 3.000; 95%CI: 1.090, 8.254; p=0.033) were variables found to have statistically significant association with anemia. Conclusion: anemia is a common complication in patients with different types of cancer. Occupation, residence, duration of cancer, stage of caner, chemotherapy, and cycles of chemotherapy significantly increased the prevalence of anemia in cancer patients.