Tien Anh Tran

Prof. Tien Anh Tran

Seoul National University, Seoul, Republic of Korea
orcid

Research Focus & Metrics

Academic Career Length

29Years (1998-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 December 2004 in Journal of Cutaneous Pathology
Verified
Journal Article
Closed access
PDF file
Tien Anh TranTien Anh Tran
Tien Anh Tran
SMSigfrid Muller
Sigfrid Muller
PCPrakash J. Chaudahri
Prakash J. Chaudahri
JCJ. Andrew Carlson
J. Andrew Carlson

1 May 1998 in Journal of Cutaneous Pathology
Verified
Journal Article
Closed access
PDF file
Tien Anh TranTien Anh Tran
Tien Anh Tran
JCJ. Andrew Carlson
J. Andrew Carlson
PBPoelinda Colis Basaca
Poelinda Colis Basaca
MMMartin C. Mihm
Martin C. Mihm

1 November 2014 in The Journal of Molecular Diagnostics
Verified
Journal Article
Open access
BLBongyong Lee
Bongyong Lee
JMJoseph Mazar
Joseph Mazar
MAMuhammad Nauman Aftab
Muhammad Nauman Aftab
FQFeng Qi
Feng Qi
JSJohn Shelley
John Shelley
RPRanjan J. Perera
Ranjan J. Perera
Prostate cancer is one of the leading causes of mortality among US males. There is an urgent unmet need to develop sensitive and specific biomarkers for the early detection of prostate cancer to reduce overtreatment and accompanying morbidity. We identified a group of differentially expressed long noncoding RNAs in prostate cancer cell lines and patient samples and further characterized six long noncoding RNAs (AK024556, XLOC_007697, LOC100287482, XLOC_005327, XLOC_008559, and XLOC_009911) in prostatic adenocarcinoma tissue samples (Gleason score >6.0) and compared them with matched normal (healthy) tissues. Interestingly, these markers were also successfully detected in patient urine samples and were found to be up-regulated when compared with normal (healthy) urine. AK024556 (SPRY4-IT1) was highly up-regulated in human prostate cancer cell line PC3 but not in LNCaP, and siRNA knockdown of SPRY4-IT1 in PC3 cells inhibited cell proliferation and invasion and increased cell apoptosis. Chromogenic in situ hybridization assay was developed to detect long noncoding RNAs in primary prostatic adenocarcinoma tissue samples, paving the way for clinical diagnostics. We believe that these results will set the stage for more extensive studies to develop novel long noncoding RNA-based diagnostic assays for early prostate cancer detection and will help to distinguish benign prostate cancer from precancerous lesions.

31 December 2008 in Journal of Cutaneous Pathology
Verified
Journal Article
Closed access
PDF file
SLSong Lu
Song Lu
Tien Anh TranTien Anh Tran
Tien Anh Tran
DJDavid M. Jones
David M. Jones
DMDale R. Meyer
Dale R. Meyer
JRJeffrey S. Ross
Jeffrey S. Ross
JCJohn Andrew Carlson
John Andrew Carlson