The importance of biomaterials lies in their fundamental roles in medical applications such as tissue engineering, drug delivery, implantable devices, and radiological phantoms, with their interactions with biological systems being critically important. In recent years, advancements in deep learning (DL), artificial intelligence (AI), machine learning (ML), supervised learning (SL), unsupervised learning (UL), and reinforcement learning (RL) have significantly transformed the field of biomaterials. These technologies have introduced new possibilities for the design, optimization, and predictive modeling of biomaterials. This review explores the applications of DL and AI in biomaterial development, emphasizing their roles in optimizing material properties, advancing innovative design processes, and accurately predicting material behaviors. We examine the integration of DL in enhancing the performance and functional attributes of biomaterials, explore AI-driven methodologies for the creation of novel biomaterials, and assess the capabilities of ML in predicting biomaterial responses to various environmental stimuli. Our aim is to elucidate the pivotal contributions of DL, AI, and ML to biomaterials science and their potential to drive the innovation and development of superior biomaterials. It is suggested that future research should further deepen these technologies’ contributions to biomaterials science and explore new application areas.
The task of semantic segmentation holds a fundamental position in the field of computer vision. Assigning a semantic label to each pixel in an image is a challenging task. In recent times, significant advancements have been achieved in the field of semantic segmentation through the application of Convolutional Neural Networks (CNN) techniques based on deep learning. This paper presents a comprehensive and structured analysis of approximately 150 methods of semantic segmentation based on CNN within the last decade. Moreover, it examines 15 well-known datasets in the semantic segmentation field. These datasets consist of 2D and 3D image and video frames, including general, indoor, outdoor, and street scenes. Furthermore, this paper mentions several recent techniques, such as SAM, UDA, and common post-processing algorithms, such as CRF and MRF. Additionally, this paper analyzes the performance evaluation of reviewed state-of-the-art methods, pioneering methods, common backbone networks, and popular datasets. These have been compared according to the results of Mean Intersection over Union (MIoU), the most popular evaluation metric of semantic segmentation. Finally, it discusses the main challenges and possible solutions and underlines some future research directions in the semantic segmentation task. We hope that our survey article will be useful to provide a foreknowledge to the readers who will work in this field.
This study focuses on the classification of six different macrofungi species using advanced deep learning techniques. Fungi species, such as Amanita pantherina, Boletus edulis, Cantharellus cibarius, Lactarius deliciosus, Pleurotus ostreatus and Tricholoma terreum were chosen based on their ecological importance and distinct morphological characteristics. The research employed 5 different machine learning techniques and 12 deep learning models, including DenseNet121, MobileNetV2, ConvNeXt, EfficientNet, and swin transformers, to evaluate their performance in identifying fungi from images. The DenseNet121 model demonstrated the highest accuracy (92%) and AUC score (95%), making it the most effective in distinguishing between species. The study also revealed that transformer-based models, particularly the swin transformer, were less effective, suggesting room for improvement in their application to this task. Further advancements in macrofungi classification could be achieved by expanding datasets, incorporating additional data types such as biochemical, electron microscopy, and RNA/DNA sequences, and using ensemble methods to enhance model performance. The findings contribute valuable insights into both the use of deep learning for biodiversity research and the ecological conservation of macrofungi species.
Background: Lung cancer is the leading cause of cancer-related deaths worldwide, ranking first in men and second in women. Due to its aggressive nature, early detection and accurate localization of tumors are crucial for improving patient outcomes. This study aims to apply advanced deep learning techniques to identify lung cancer in its early stages using CT scan images. Methods: Pre-trained convolutional neural networks (CNNs), including MobileNetV2, ResNet152V2, InceptionResNetV2, Xception, VGG-19, and InceptionV3, were used for lung cancer detection. Once the disease was identified, the tumor’s region was segmented using models such as UNet, SegNet, and InceptionUNet. Results: The InceptionResNetV2 model achieved the highest detection accuracy of 98.5%, while UNet produced the best segmentation results, with a Jaccard index of 95.3%. Conclusions: The study demonstrates the effectiveness of deep learning models, particularly InceptionResNetV2 and UNet, in both detecting and segmenting lung cancer, showing significant potential for aiding early diagnosis and treatment. Future work could focus on refining these models and exploring their application in other medical domains.
Fungi play a critical role in ecosystems, contributing to biodiversity and providing economic and biotechnological value. In this study, we developed a novel deep learning-based framework for the classification of seven macrofungi species from the genera Mycena and Marasmius, leveraging their unique ecological and morphological characteristics. The proposed approach integrates a custom convolutional neural network (CNN) with a self-organizing map (SOM) adapted for supervised learning and a Kolmogorov–Arnold Network (KAN) layer to enhance classification performance. The experimental results demonstrate significant improvements in classification metrics when using the CNN-SOM and CNN-KAN architectures. Additionally, advanced pretrained models such as MaxViT-S and ResNetV2-50 achieved high accuracy rates, with MaxViT-S achieving 98.9% accuracy. Statistical analyses using the chi-square test confirmed the reliability of the results, emphasizing the importance of validating evaluation metrics statistically. This research represents the first application of SOM in fungal classification and highlights the potential of deep learning in advancing fungal taxonomy. Future work will focus on optimizing the KAN architecture and expanding the dataset to include more fungal classes, further enhancing classification accuracy and ecological understanding.
This study presents a novel approach for classifying Discomycetes species using deep learning and explainable artificial intelligence (XAI) techniques. The EfficientNet-B0 model achieved the highest performance, reaching 97% accuracy, a 97% F1-score, and a 99% AUC, making it the most effective model. MobileNetV3-L followed closely, with 96% accuracy, a 96% F1-score, and a 99% AUC, while ShuffleNet also showed strong results, reaching 95% accuracy and a 95% F1-score. In contrast, the EfficientNet-B4 model exhibited lower performance, achieving 89% accuracy, an 89% F1-score, and a 93% AUC. These results highlight the superior feature extraction and classification capabilities of EfficientNet-B0 and MobileNetV3-L for biological data. Explainable AI (XAI) techniques, including Grad-CAM and Score-CAM, enhanced the interpretability and transparency of model decisions. These methods offered insights into the internal decision-making processes of deep learning models, ensuring reliable classification results. This approach improves traditional taxonomy by advancing data processing and supporting accurate species differentiation. In the future, using larger datasets and more advanced AI models is recommended for biodiversity monitoring, ecosystem modeling, medical imaging, and bioinformatics. Beyond high classification performance, this study offers an ecologically meaningful approach by supporting biodiversity conservation and the accurate identification of fungal species. These findings contribute to developing more precise and reliable biological classification systems, setting new standards for AI-driven research in biological sciences.