Recently, analyses of the air quality in Pakistan have received significant interest, especially regarding the impact of air pollutant concentrations on human health. The Atlas of Baseline Environmental Profiling along the China-Pakistan Economic Corridor (CPEC) at five locations in Gilgit-Baltistan (GB) is a major landmark in this regard due to the presence of massive glaciers in the region, which are considered as water reserves for the country. Using various statistical measurements, the air quality was analyzed at the studied geographic locations. Further, air quality was evaluated based on air pollutant data acquired from ambient air monitoring laboratories. For example, 24 h concentrations of particulate matter (PM_2.5) were found to range from 25.4 to 60.1 µg/m³, with peaks in the winter season at Gilgit. It was found that PM_2.5 values were 1.7 and 1.3 times greater than National Environmental Quality Standards (NEQS) standards only at Gilgit and Chilas, respectively, and 1.5 to 4 times greater than the World Health Organization (WHO) standards at all locations. Similarly, PM_2.5 concentrations were found to range from 31.4 to 63.9 µg/m³, peaking at Chilas in summer 2020. The observed values were 1.1 to 1.8 times and 2 to 4.2 times greater than the NEQS and WHO standards, respectively, at all locations. In addition, the average peaks of black carbon (BC) were measured at Gilgit, both in winter (16.21 µg/m³) and summer (7.83 µg/m³). These elevated levels could be attributed to the use of heavy diesel vehicles, various road activities and different meteorological conditions. Pollutants such as carbon monoxide (CO), sulfur dioxide (SO₂), nitrogen oxides (NO_X) and ozone (O₃) were found to be within NEQS and WHO limits. Based on air quality metrics, the effect of PM_2.5 on air quality was found to be moderate in Sost, Hunza and Jaglot, while it was at unhealthy levels at Gilgit and Chilas in the winter of 2019; moderate levels were observed at Sost while unhealthy levels were detected at the remaining locations in the summer of 2020. There are no specific guidelines for BC. However, it is associated with PM_2.5, which was found to be a major pollutant at all locations. The concentrations of CO, SO₂ and O₃ were found to be at safe levels at all locations. The major fraction of air masses is received either locally or from transboundary emissions. This study demonstrates that PM_2.5 and BC are the major and prevailing air pollutants within the study region, while other air pollutants were found to be within the permissible limits of the WHO and NEQS.