In this work, the influences of flexibility and surface texture on the performances of a finite-long journal bearing have been investigated theoretically. Reynolds equation has been solved by using finite difference method. In this study, Winkler foundation model has been used to calculate the elastic deformation of the bearing bush or housing. The steady-state characteristics of a lubricated finite-long journal bearing are studied in the textured and untextured bearing surface, respectively. The simulation results of the present study indicate that the surface texture can appreciably change the shaft center-line locus and oil film pressure distribution comparatively to the smooth case. The texture arrangements on the bearing surface, the texture number in the circumferential or axial directions, and the texture depth in the radial direction, all of them have significant influences on the static characteristics of a flexible journal bearing.

Klebsiella pneumoniae has become one of the most intractable gram-negative pathogens infecting humans and animals due to its severe antibiotic resistance. Bacteriophages and protein products derived from them are receiving increasing amounts of attention as potential alternatives to antibiotics. In this study, we isolated and investigated the characteristics of a new lytic phage, P1011, which lyses K5 K. pneumoniae specifically among 26 serotypes. The K5-specific capsular polysaccharide-degrading depolymerase dep1011 was identified and expressed. By establishing murine infection models using bovine strain B16 (capable of supporting phage proliferation) and human strain KP181 (incapable of sustaining phage expansion), we explored the safety and efficacy of phage and dep1011 treatments against K5 K. pneumoniae. Phage P1011 resulted in a 60% survival rate of the mice challenged with K. pneumoniae supporting phage multiplication, concurrently lowering the bacterial burden in their blood, liver, and lungs. Unexpectedly, even when confronted with bacteria impervious to phage multiplication, phage therapy markedly decreased the number of viable organisms. The protective efficacy of the depolymerase was significantly better than that of the phage. The depolymerase achieved 100% survival in both treatment groups regardless of phage propagation compatibility. These findings indicated that P1011 and dep1011 might be used as potential antibacterial agents to control K5 K. pneumoniae infection.