Prof. Dr. Torao Ishida
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Academic Career Length
21Years (2006-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications2 October 2012 in Evidence-Based Complementary and Alternative Medicine
Journal Article
Banaba (Lagerstroemia speciosa L.) extracts have been used for many years in folk medicine to treat diabetes, with the first published research study being reported in 1940. This paper summarizes the current literature regarding Banaba and its constituents. The hypoglycemic effects of Banaba have been attributed to both corosolic acid as well as ellagitannins. Studies have been conducted in various animal models, human subjects, and in vitro systems using water soluble Banaba leaf extracts, corosolic acid, and ellagitannins. Corosolic acid has been reported to decrease blood sugar levels within 60 min in human subjects. Corosolic acid also exhibits antihyperlipidemic and antioxidant activities. The beneficial effects of Banaba and corosolic acid with respect to various aspects of glucose and lipid metabolism appear to involve multiple mechanisms, including enhanced cellular uptake of glucose, impaired hydrolysis of sucrose and starches, decreased gluconeogenesis, and the regulation of lipid metabolism. These effects may be mediated by PPAR and other signal transduction factors. Banaba extract, corosolic acid, and other constituents may be beneficial in addressing the symptoms associated with metabolic syndrome, as well as offering other health benefits.
1 April 2016 in Neuroscience Letters
Journal Article
NTNobuyuki Tanahashi
Nobuyuki Tanahashi
KTKen Takagi
Ken Takagi
NANozomi Amagasu
Nozomi Amagasu
GWGuifeng Wang
Guifeng Wang
KMKaito Mizuno
Kaito Mizuno
Torao Ishida +2
8 December 2016 in Journal of Acupuncture and Meridian Studies
Journal Article
KTKen Takagi
Ken Takagi
NTNobuyuki Tanahashi
Nobuyuki Tanahashi
NANozomi Amagasu
Nozomi Amagasu
KMKaito Mizuno
Kaito Mizuno
JKJun Kawanokuchi
Jun Kawanokuchi
Torao Ishida +1
A previous study on rats showed that simultaneous acupuncture stimulation at the “Bai-Hui” (GV 20) and the “Yintáng” (Ex-HN3) acupoints alleviated the state of depression to an extent similar to that achieved by pharmacotherapy. This study investigated whether the alleviation of the depressed state required simultaneous acupuncture at these two acupuncture points. For the purposes of testing the effect of acupuncture on depressive symptoms, we treated a depression model rat, where depression had been induced by using a mild water-immersion stress technique, with either acupuncture stimulation at only one acupuncture point (GV 20 or Ex-HN3) or an antidepressant, and we measured the immobile time for evaluating the state of depression. Anxiety, as a symptom commonly associated with depression, was also evaluated by measuring the number of head dips. Neither the immobile time nor the number of head dips decreased upon acupuncture stimulation. From this study, single acupuncture stimulation at either “GV 20” or “Ex-HN3” alleviated neither the state of depression nor the anxiety. The water-immersion stress used to make the depression model rats was shown not to induce anxiety; however, the stress induced by immobilizing the rats for acupuncture stimulation did lead to anxiety.
1 March 2006 in Chinese Journal of Integrative Medicine
Journal Article
ZWZhang Wen-Ping
Zhang Wen-PingTorao IshidaJournal Article
Torao IshidaKTKen Takagi
Ken Takagi
Guifeng WangNTNobuyuki Tanahashi
Nobuyuki TanahashiJKJun Kawanokuchi
Jun Kawanokuchi
Ning Ma +2
(1) Background: It is our purpose to identify the differences in the changes in Complement C5a receptor 1 (C5aR1) levels showing the degree of inflammation at onset and Immunoglobulin G (IgG) levels showing the extent of survival of the virus fragments after recovery between coronavirus disease 2019 (COVID-19) and pneumonia coronavirus disease (non-COVID-19) for saving patients’ lives. (2) Methods: First, the studies showing these markers’ levels in individual patients before and after the passage of time were selected from the PubMed Central® databases with the keywords (((COVID-19) AND individual) NOT review) AND C5a/IgG. Then, no changes in these markers’ levels with conventional analyses were selected from the studies. Finally, the no changes were reexamined with our new two-tailed t-test using the values on the regression line between initial levels and changed levels instead of the mean or median of changed levels as the expected values of changed levels. (3) Results: Not conventional analyses but our new t-test suggested a greater increase in C5aR1-levels at onset and a smaller decrease in IgG-levels after recovery in COVID-19 patients than non-COVID-19 patients. (4) Conclusion: Our new t-test also should be used in clinics for COVID-19 patients.
1 June 2014 in World Journal of Acupuncture - Moxibustion
Journal Article
GWGui-Feng Wang
Gui-Feng Wang
KTKen Takagi
Ken Takagi
KMKaito Mizuno
Kaito Mizuno
YSYoshinori Sunami
Yoshinori Sunami
YGYi Guo
Yi Guo
Torao Ishida +2
About Me
Torao Ishida is an Honorary Professor at Suzuka University of Medical Science, a Member of the Institute of Traditional Chinese Medicine, and Director of the Japanese Society of Medicinal Dietetics. Educational background: 1970, Ph.D., School of Science, Graduate School of the University of Tokyo. Work experience: 1962–1998, Member of Asahi Chemical Industry Co. Ltd., Director General of the Institute of Life Science from 1990; 1998–2019, Director, Councilor, and Professor of Suzuka University of Medical Science. Research interests: anticancer drug development, medical biology, and immunology. Memberships of professional societies and awards received: Pharmaceutical Society of Japan, the Japanese Society of Medicinal Dietetics; 1996, Asahi Prize, Japan Institute of Invention and Innovation; 1997, Person of Invention Research Merit, Tokyo Metropolitan Government; 2007, Science and Technology Prize, Japanese Minister of Education, Culture, Sports, Science and Technology Commendation; Special Prize by Asahi Kasei Co.; the Prize of the Chairman of the Joint Meeting of the 11th Japanese Association for Alternative, Complementary and Traditional Medicine and the 7th Japanese Medical Treatment Society; 2009, the International AMS Awards of the Symposium on Acupuncture and Meridian Studies 2009.