Nikolay Dimitrov Kanazirski

Dr. Nikolay Dimitrov Kanazirski


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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NKNikolay Dimitrov Kanazirski
Nikolay Dimitrov Kanazirski
DVDiyana Ivanova Vladova
Diyana Ivanova Vladova
DNDeyan Neychev
Deyan Neychev
Ralitsa RaychevaRalitsa Raycheva
Ralitsa Raycheva
PHPetya Georgieva Hadzhigeorgieva-Kanazirska
Petya Georgieva Hadzhigeorgieva-Kanazirska
The placement of dental screw implants typically involves the use of rotary techniques and drills to create a bone bed. This study explores the potential benefits of combining this method with an Er:YAG laser. Split osteotomies were performed on 10 jaws of euthanized domestic pigs (Sus scrofa domestica), with 12 mandibular implant osteotomies in each jaw, divided into 4 groups. In order to make a comprehensive assessment of the effect of Er:YAG lasers, histomorphological techniques were used to measure the reduction in amorphous layer thickness after Er:YAG laser treatment, both with and without the placement of dental screw implants from different manufacturers. Following bone decalcification and staining, the thickness of the amorphous layer was measured in four groups: Group A—osteotomy performed without Er:YAG laser treatment—had amorphous layer thicknesses ranging from 21.813 to 222.13 µm; Group B—osteotomy performed with Er:YAG laser treatment—had amorphous layer thicknesses ranging from 6.08 to 64.64 µm; Group C—an implant placed in the bone without laser treatment—had amorphous layer thicknesses of 5.90 to 54.52 µm; and Group D—an implant placed after bone treatment with Er:YAG laser—had amorphous layer thicknesses of 1.29 to 7.98 µm. The examination and photomicrodocumentation was performed using a LEICA DM1000 LED microscope (Germany) and LAS V 4.8 software (Leica Application Suite V4, Leica Microsystems, Germany). When comparing group A to group B and group C to D, statistically significant differences were indicated (p-value = 0.000, p < 0.05). The study demonstrates the synergistic effects and the possibility of integrating lasers into the conventional implantation protocol. By applying our own method of biomodification, the smear layer formed during rotary osteotomy can be reduced using Er:YAG lasers. This reduction leads to a narrower peri-implant space and improved bone-to-implant contact, facilitating accelerated osseointegration.

11 May 2024 in Diagnostics
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PHPetya Georgieva Hadzhigeorgieva-Kanazirska
Petya Georgieva Hadzhigeorgieva-Kanazirska
NKNikolay Dimitrov Kanazirski
Nikolay Dimitrov Kanazirski
ISIliyana Stoeva
Iliyana Stoeva
The objective of this study was to compare the results of the measurements made using two methods for determining the retromolar eruption spaces and the mesiodistal inclinations of impacted mandibular third molars. These are the main parameters based on which the eruption of these teeth can be predicted. A Sirona GALILEOS Compact/Comfort CBCT scanner was used for the study. A total of 127 patients were included in the study. We made the measurements using our integrated method and the standard method used in the dental practice for determining the eruption space and the mesiodistal inclination of these teeth, and then we compared the results. The mean difference between the two methods for estimating the retromolar space deficiency on the left was 1.70 mm and standard deviation (SD) 2.95; mean error of the mean was 0.29; and Student t-test (paired t-test) = 5.86, significant level of the correlation was 0.001, <0.05. Regarding the teeth on the right, it was mean 1.59 mm and standard deviation (SD) 2.98; mean error of the mean was 0.31. The t-test performed found a statistically significant difference between the methods in determining the retromolar eruption spaces (t-test (paired t-test) = 5.13; significant level of the correlation 0.001; p < 0.05). The mean difference (in degrees) between the measurements of the inclinations of the teeth on the left using the two methods was 3, 50°; SD = 7.25; mean error of the mean = 1.81; t-test = 2.481; significant level of the correlation 0.025; and p > 0.05. As for the teeth on the right, it was 2.41°, SD = 9.57, mean error of the mean = 2.39, t-test 0.175, significant level of the correlation = 0.863, and >0.05. No statistically significant difference was found between the two methods in measuring the inclinations of impacted third molars. The conclusion of our study is that the determination of the mesiodistal inclination of the teeth and the available eruption space using the method developed by us is more accurate compared to the standard method, because constant points and planes are used. This method allows for predicting the eruption of impacted mandibular third molars.

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NKNikolay Dimitrov Kanazirski
Nikolay Dimitrov Kanazirski
DNDeyan Neychev
Deyan Neychev
PKPetya Kanazirska
Petya Kanazirska
TMTsonka Miteva-Katrandzhieva
Tsonka Miteva-Katrandzhieva
Background: Er:YAG laser (λ = 2940 nm) biomodification of the implant osteotomy site removes the smear layer after rotary preparation and may enhance bone-implant contact. This randomized controlled clinical study evaluated implant stability dynamics following Er:YAG laser biomodification using resonance frequency analysis (RFA). Methods: Ninety patients were randomized 1:1 into a case group (n = 45; rotary osteotomy + Er:YAG biomodification; 400 mJ, 17 Hz) and a control group (n = 45; rotary osteotomy alone). Implant stability quotient (ISQ) was measured by RFA in vestibulo-oral (VO) and mesiodistal (MD) directions at placement, days 10, 20, 30, and month 3. Results: The case group showed significantly higher ISQ values at all time points in both directions (t-test, p < 0.05). Repeated measures ANOVA revealed a significant time × group interaction in the MD direction (F = 14.461, p < 0.001, partial η2 = 0.341). Primary VO ISQ: 75.04 ± 4.27 (cases) vs. 72.29 ± 3.38 (controls); primary MD ISQ: 76.49 ± 4.29 vs. 72.89 ± 2.29. The proportion achieving ISQ ≥ 70 was consistently higher in the case group. Conclusions: Er:YAG laser biomodification combined with rotary osteotomy yields higher, more stable ISQ values throughout early healing in mandibular D2/D3 bone, potentially supporting shorter healing intervals and early loading in selected clinical situations.