Lois W. Sayrs

Dr. Lois W. Sayrs

orcid

Research Focus & Metrics

Academic Career Length

36Years (1991-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 February 2021 in Journal of Pediatric Surgery
Verified
Journal Article
Closed access
DNDavid M Notrica
David M Notrica
LKLisa Kirsch
Lisa Kirsch
SMShivani Misra
Shivani Misra
CKCara Kelly
Cara Kelly
JGJodie Greenberg
Jodie Greenberg
LSLois W. Sayrs
Lois W. Sayrs

22 October 2020 in Journal of Interpersonal Violence
Verified
Journal Article
Closed access
PDF file
LSLois W. Sayrs
Lois W. Sayrs
JOJ. Bryce Ortiz
J. Bryce Ortiz
DNDavid M. Notrica
David M. Notrica
LKLisa Kirsch
Lisa Kirsch
CKCara Kelly
Cara Kelly
Rachel K. RoweRachel K. Rowe
Rachel K. Rowe
Over half of fatal pediatric traumatic brain injuries are estimated to be the result of physical abuse, i.e., abusive head trauma (AHT). Although intimate partner violence (IPV) is a well-established risk for child maltreatment, little is known about IPV as an associated risk factor specifically for AHT. We performed a single-institution, retrospective review of all patients (0–17 years) diagnosed at a Level 1 pediatric trauma center with head trauma who had been referred to an in-hospital child protection team for suspicion of AHT between 2010 and 2016. Data on patient demographics, hospitalization, injury, family characteristics, sociobehavioral characteristics, physical examination, laboratory findings, imaging, discharge, and forensic determination of AHT were extracted from the institution’s forensic registry. Descriptive statistics (mean, median), chi-square and Mann–Whitney U tests were used to compare patients with fatal head injuries to patients with nonfatal head injuries by clinical characteristics, family characteristics, and forensic determination. Multiple logistic regression was used to estimate adjusted odds ratios for the presence of IPV as an associated risk of AHT while controlling for other clinical and family factors. Of 804 patients with suspicion for AHT in the forensic registry, there were 240 patients with a forensic determination of AHT; 42 injuries were fatal. There were 101 families with a reported history of IPV; 64.4% of patients in families with reported IPV were <12 months of age. IPV was associated with a twofold increase in the risk of AHT (Exp( β ) = 2.3 [ p = .02]). This study confirmed IPV was an associated risk factor for AHT in a single institution cohort of pediatric patients with both fatal and nonfatal injuries. Identifying IPV along with other family factors may improve detection and surveillance of AHT in medical settings and help reduce injury, disability, and death.

6 July 2020 in Journal of Trauma and Acute Care Surgery
Verified
Journal Article
Closed access
DNDavid M. Notrica
David M. Notrica
LSLois W. Sayrs
Lois W. Sayrs
NKNidhi Msc Krishna
Nidhi Msc Krishna
KDKatherine P. Davenport
Katherine P. Davenport
RJRamin Jamshidi
Ramin Jamshidi
LMLisa E McMahon
Lisa E McMahon
BACKGROUND: Helmets are effective in reducing traumatic brain injury. However, population effects of helmet laws have not been well described. This study assesses the impact of helmet laws on the motorcycle (MC) fatality rate in the United States from 1999 to 2015. METHODS: Fatality Analysis Reporting System MC fatalities (aged ≥16 years), crash characteristics, and MC-related laws were collected by year for all 50 states from 1999 to 2015 to create a pooled time series. Generalized linear autoregressive modeling was applied to assess the relative contribution of helmet laws to the MC fatality rate while controlling for other major driver laws and crash characteristics. RESULTS: Universal helmet laws were associated with a 36% to 45% decline in the motorcycle crash mortality rate during the study period across all age cohorts (unstandardized regression coefficients are reported): 16 to 20 years, B = −0.45 (p < 0.05); 21 to 55 years, B = −0.42 (p < 0.001); 56 to 65 years, B = −0.38 (p < 0.04); and older than 65 years, B = −0.36 (p < 0.02). Partial helmet laws were associated with a 1% to 81% increase in the fatality rate compared with states with no helmet laws and a 22% to 45% increase compared with universal laws. Helmet usage did not attenuate the countervailing effect of weaker partial laws for 16 to 20 years (B = 0.01 [p < 0.001]). Other laws associated with a declining motorcycle crash mortality rate included the following: social host/overservice laws, 21 to 55 years (B = −0.38 [p < 0.001]); 56 to 65 years (B = −0.16 [p < 0.002]), and older than 65 years (B = −0.12 [p < 0.003]); laws reducing allowable blood alcohol content, 21 to 55 years (B = −4.9 [p < 0.02]); and laws limiting passengers for new drivers 16 to 20 years (B = −0.06 [p < 0.01]). CONCLUSION: During the period of the study, universal helmet laws were associated with a declining mortality rate, while partial helmet laws were associated with an increasing mortality rate. Other state driver laws were also associated with a declining rate. In addition to universal helmet laws, advocating for strict alcohol control legislation and reevaluation of licenses in older riders could also result in significant reduction in MC-related mortality. LEVEL OF EVIDENCE: Prognostic and epidemiological, level III.

15 October 2025 in European Spine Journal
Verified
Journal Article
Closed access
PDF file
JNJohn Ngo
John Ngo
KAKiran Athreya
Kiran Athreya
BEBrandon Ehrlich
Brandon Ehrlich
LSLois W. Sayrs
Lois W. Sayrs
TMTricia Morphew
Tricia Morphew
AAAfshin Aminian
Afshin Aminian

1 August 2024 in Journal of Perinatology
Verified
Journal Article
Closed access
PDF file
MMMeghan Moroze
Meghan Moroze
TMTricia Morphew
Tricia Morphew
LSLois W. Sayrs
Lois W. Sayrs
AEAzam Eghbal
Azam Eghbal
WHW. Nathan Holmes
W. Nathan Holmes
MMMichel Mikhael
Michel Mikhael

20 January 2023 in Journal of Pediatric Surgery
Verified
Journal Article
Closed access
RJRebecca John
Rebecca John
PYPeter T. Yu
Peter T. Yu
TRTroy Reyna
Troy Reyna
YGYigit Guner
Yigit Guner
PPPatcharada Promprasert
Patcharada Promprasert
SASaeed Awan
Saeed Awan