The COVID-19 pandemic has worsened the psychological and social stress levels of university students due to physical illness, internet dependence, a lack of social activities, and home confinement. Therefore, early stress detection is crucial for their successful academic performance and mental well-being. The advent of machine learning (ML)-based prediction models can have a crucial impact in predicting stress at its early stages and taking necessary steps for the well-being of individuals. This study aims to develop a reliable machine learning-based prediction model for perceived stress prediction and validate the model using real-world data collected through an online survey among 444 university students from different ethnicity. The machine learning models were built using supervised machine learning algorithms. Principal Component Analysis (PCA) and the chi-squared test were employed as feature reduction techniques. Moreover, Grid Search Cross-Validation (GSCV) and Genetic Algorithm (GA) were employed for hyperparameter optimization (HPO). According to the findings, around 11.26% of individuals were identified with high levels of social stress. In comparison, approximately 24.10% of people were found to be suffering from extremely high psychological stress, which is quite alarming for students' mental health. Furthermore, the prediction results of the ML models demonstrated the most remarkable accuracy (80.5%), precision (1.000), F1 score (0.890), and recall value (0.826). The Multilayer Perceptron model was shown to have the maximum accuracy when combined with PCA as a feature reduction approach and GSCV for HPO. The convenience sampling technique used in this study only considers self-reported data, which may have biased results and lack generalizability. Future research should consider a large sample of data and focus on tracking long-term impacts with coping strategies and interventions. The results of this study can be used to develop strategies to mitigate adverse effects and promote student well-being during pandemics and other stressful situations.

Bone marrow transplant (BMT) is an effective surgical treatment for bone marrow-related disorders. However, several associated risk factors can impair long-term survival after BMT. Machine learning (ML) technologies have been proven useful in survival prediction of BMT receivers along with the influences that limit their resilience. In this study, an efficient classification model predicting the survival of children undergoing BMT is presented using a public dataset. Several supervised ML methods were investigated in this regard with an 80-20 train-test split ratio. To ensure prediction with minimal time and resources, only the top 11 out of the 59 dataset features were considered using Chi-square feature selection method. Furthermore, hyperparameter optimization (HPO) using the grid search cross-validation (GSCV) technique was adopted to increase the accuracy of prediction. Four experiments were conducted utilizing a combination of default and optimized hyperparameters on the original and reduced datasets. Our investigation revealed that the top 11 features of HPO had the same prediction accuracy (94.73%) as the entire dataset with default parameters, however, requiring minimal time and resources. Hence, the proposed approach may aid in the development of a computer-aided diagnostic system with satisfactory accuracy and minimal computation time by utilizing medical data records.

This paper presents a novel approach of investigating registration performance of different Multiple Sclerosis (MS) affected brain tissues with brain atlas by image inpainting technique. MS is an immune-mediated disorder that develops from an interaction of the individual's genetics and unidentified environmental causes. In order to carry out medical diagnosis in proper time image registration plays a vital role. In this work, different MS lesions are introduced in healthy brain tissue in order to analyse and characterize according to their characteristics (T1 weighted image, T2 weighted image) because MS lesions create a strong bias in image registration process. Thus, image inpainting technique appears to be a handy tool to reduce the bias efficiently. It is evident that the proposed inpainting algorithm performs satisfactorily with a view to reducing the bias in the registration step. The overall performance of the technique is evaluated by utilizing Dice and Jaccard scores. MATLAB and FSL software are used to perform the simulation.