We describe a patient with goose-neck posture as the presenting form of cervical dystonia. In our case, the bilateral semispinalis capitis muscles were hypertrophic, thick, and overactive while both splenius capitis and sternocleidomastoid muscles were normal. In this single case experience, we demonstrated that the semispinalis capitis muscle may play a primary role in causing a goose-neck posture and the observed forward sagittal shift may be a compensatory or overflow activity of neck flexor muscles. Therefore, botulinum toxin injection to the semispinalis capitis muscles can be considered in the management of patients with goose-neck posture.

Background: Cerebral venous thrombosis (CVT) is a challenging condition with potential long-term consequences, but it is also a treatable disorder that offers the possibility of complete recovery. This study was conducted to comprehensively investigate the clinical features, brain imaging findings, and treatment outcomes of patients diagnosed with cerebral venous thrombosis. Materials and Methods: Conducted as a cross-sectional descriptive study, patients diagnosed with cerebral venous thrombosis were enrolled at Can Tho Central General Hospital between January 2021 and June 2022. Results: Notably, a substantial proportion of patients (83.4%) exhibited signs of brain damage, with intracranial hemorrhage (50%), brain infarction (30.9%), subarachnoid hemorrhage (16.6%), and hemorrhagic infarct (4.7%) being the predominant findings. Thrombosis primarily affected the superior sagittal sinus (85.7%), transverse sinus (52.4%), and sigmoid sinus (42.8%). All patients received anticoagulation treatment, resulting in a favorable recovery upon hospital discharge for the majority (90.5%), while a small percentage (9.5%) experienced critical illness or death. Conclusion: Our study on cerebral venous thrombosis found diverse clinical presentations, primarily headache. Intracranial hemorrhage was common, affecting superior sagittal, transverse, and sigmoid sinuses. Most patients achieved favorable recoveries with anticoagulation treatment, emphasizing early intervention’s importance. The plain language summary: Cerebral venous thrombosis (CVT) is a less common condition when compared to arterial thrombosis, which has received more research attention. However, CVT has not received the same level of focus and investigation. The study aimed to comprehensively examine the clinical features, brain imaging findings, and treatment outcomes of patients diagnosed with CVT. The findings revealed that patients with CVT commonly presented with symptoms such as headache, limb weakness, seizures, vomiting, and consciousness disorders. Neuroimaging showed significant brain damage, including intracranial hemorrhage and brain infarction. However, with appropriate anticoagulation treatment, the majority of patients achieved favorable recoveries. The study emphasizes the importance of early intervention and highlights the need for improved diagnostic accuracy and treatment strategies for CVT.

Background: In Vietnam, there is limited research on the role of nerve conduction in myasthenia gravis and its association with clinical features. Objective: This study aims to describe the electrophysiological features in patients with myasthenia gravis. Methods: This descriptive study was conducted from September 2019 to December 2021. The study included 33 myasthenia gravis patients who sought medical consultation or received inpatient treatment during this period. The Myasthenia Gravis Foundation of America classifies myasthenia gravis into five groups: I, IIa, IIb, IIIa, IIIb, IVa, IVb, and V. Notably, Group I involves pure ocular weakness, whereas Group a primarily impacts limb and axial muscles, and Group b mainly affects bulbar and respiratory muscles. Results: The study revealed that motor and sensory nerve conduction in the upper and lower limbs were within normal limits for the patient group under evaluation. Repetitive nerve stimulation testing at a frequency of 3 Hz showed positive results in 66.7% of myasthenia gravis patients. Myasthenia gravis patients displayed distinct clinical symptoms, with ptosis being the most common (87.9%). Myasthenia Gravis Foundation of America classification indicated the highest proportion in subgroup IIa (24.2%), with myasthenia gravis predominating in limb and axial muscles (Group a) observed in 51.5% of cases. Needle electromyography showed no abnormalities in myasthenia gravis patients. There was an association between acetylcholine receptor antibody titers and the results of the 3 Hz repetitive nerve stimulation test in myasthenia gravis patients, with a significance of p = 0.002. Conclusion: Nerve conduction studies should be performed in patients with suspected neuromuscular disorders to aid in differential diagnosis and definitive diagnosis of myasthenia gravis.

Very few studies worldwide have assessed the estimated glomerular filtration rate (eGFR) using serum cystatin C (ScysC) in comparison to the gold standard measured glomerular filtration rate (mGFR) with a gamma camera technique using 99m–Technetium—Diethylene Triaminepentoacetic Acid (^99mTc–DTPA). To determine the eGFR formula with the most accurate estimate of glomerular filtration rate when compared with mGFR in a healthy population in Vietnam. We conducted a cross-sectional descriptive study of more than 100 adults without hypertension. The study subjects were examined for general characteristics and blood biochemistry tests to assess eGFR, and the glomerular filtration rate was measured using ^99mTc–DTPA with the Gates technique to record mGFR. The estimated values of the eGFR formula were evaluated and compared with the actual mGFR using ^99mTechnetium–DTPA. Serum creatinine (Scr) concentration showed a significant difference between males and females: 0.9 ± 0.1 versus 0.8 ± 0.1 (P < .001), while ScysC concentration did not show this difference. The mGFR in the age groups < 40, 40 to 59, and ≥ 60: 105.0 ± 9.9, 94.8 ± 8.6, and 93.4 ± 10.6, respectively (P < .001). The eGFR-CKD-EPI-cystatin C 2012 formula showed the highest positive correlation with mGFR (ΔGFR = −1.6, R = 0.68, P < .001). eGFR calculated using cystatin C does not require sex adjustment, whereas, for creatinine, sex adjustment is necessary. The eGFR-CKD-Epi-CysC formula showed the lowest difference and a strong correlation with mGFR.

Đặt vấn đề: Nhồi máu não tái diễn (NMNTD) là biến cố nặng, làm tăng nguy cơ tử vong và tàn phế. Việc xác định tỉ lệ và các yếu tố liên quan giúp nâng cao hiệu quả điều trị và dự phòng. Mục tiêu: Xác định tỉ lệ, nguyên nhân và các yếu tố nguy cơ liên quan đến NMNTD trong 12 tháng sau đợt nhồi máu não đầu tiên tại Bệnh viện Đa khoa Trung ương Cần Thơ giai đoạn 2022–2024. Phương pháp: Nghiên cứu đoàn hệ tiến cứu gồm 890 bệnh nhân nhồi máu não với thời gian theo dỗi ≥12 tháng. Kết quả: Tỉ lệ NMNTD sau 12 tháng là 6,7%. Tỉ lệ NMNTD tích lũy theo thời gian: 1 tháng 2%; 6 tháng 3,6 %; 12 tháng 6,7%. Nguyên nhân theo phân loại TOAST, NMNTD gặp nhiều nhất ở nhóm xơ vữa mạch lớn (LAA: 38,2,2%) và nguồn gốc tim (CE: 24,7%), thấp nhất ở ổ khuyết (SVD: 21,3%). Phân tích Cox cho thấy các yếu tố nguy cơ độc lập gồm: tuổi ≥65, THA, ĐTĐ, ngưng thuốc kháng đông hoặc Chống kết tập tiểu cầu (CKTTC). Kết luận: NMNTD tại bệnh viện chiếm tỉ lệ tương tự các nghiên cứu quốc tế (5–7%). Nguy cơ tái phát cao ở nhóm LAA và CE, đặc biệt ở bệnh nhân ngưng thuốc kháng đông/CKTTC.