Prof. Dr. Francesco Fedele is a Full Professor of Cardiology and Director of the Specialization School for Cardiologist of “La Sapienza” University of Rome, and Chief of Cardiology at the Department of Cardiovascular, Respiratory, Nephrology and Geriatrics Sciences at the “Policlinico Umberto I” Hospital. He has been a principal investigator in several International Clinical Trials and authored over 700 publications on national and international journals in research fields such as cardiorespiratory pathophysiology, pathophysiology of ischemic heart disease, acute myocardial infarction, systemic and pulmonary hypertension, heart failure, echocardiography, and clinical pharmacological therapy.