Many different elements of patient monitoring and treatment can be supported by implantable devices, which have proven to be extremely reliable and efficient in the medical profession. Medical professionals can use the data they collect to better diagnose and treat patients as a result. The devices’ power sources, on the other hand, are battery-based, which introduces a slew of issues. As part of this review, we explore the use of harvesters in implanted devices and evaluate various materials and procedures and look at how new and improved circuits can enable the harvesters to sustain medical devices.
1 February 2025 in Bulletin of Electrical Engineering and Informatics
Electrospinning has emerged as a simple and cost-effective technique for producing polymer nanofibers, offering a versatile approach for creating nanostructured fibers from a wide range of polymer materials. The pharmaceutical field has particularly welcomed the advent of electrospun nanofibers, as they hold immense potential for revolutionizing drug delivery systems. The recent surge of interest in electrospun nanofibers can be attributed to their unique characteristics, including elasticity and biocompatibility, which make them highly suitable for various biomedical applications. By incorporating functional ingredients into blends of nanostructured fibers, the capabilities and reliability of drug delivery devices have been significantly enhanced. This review aims to provide a comprehensive summary of recent research endeavors focusing on the concept of nanofibrous mesh and its multifaceted applications. With an emphasis on the simplicity of fabrication and the virtually limitless combinations of materials achievable through this approach, nanofibrous meshes hold the promise of transforming specific treatment modalities. By streamlining the delivery of therapeutic agents and offering enhanced control over drug release kinetics, nanofibrous meshes may herald a new era in targeted and personalized medicine.
1 February 2025 in International Journal of Electrical and Computer Engineering (IJECE)
Cardiovascular disease consistently occupies a prominent position among the leading global causes of mortality. Continuous and real-time monitoring of cardiovascular signs over an extended duration is necessary to identify irregularities and prompt timely intervention. Due to this reason, researchers have invested heavily in developing adaptive sensors that may be worn or implanted and continuously monitor numerous vital physiological characteristics. Mechanical sensors represent a category of devices capable of precisely capturing the temporal variations in pressure within the heart and arteries. Mechanical sensors possess inherent advantages such as exceptional precision and a wide range of adaptability. This article examines four distinct mechanical sensor technologies that rely on capacitive, piezoresistive, piezoelectric, and triboelectric principles. These technologies show great potential as novel approaches for monitoring the cardiovascular system. The subsequent section provides a comprehensive analysis of the biomechanical components of the cardiovascular system, accompanied by an in-depth examination of the methods employed to monitor these intricate systems. These systems measure blood and endocardial pressure, pulse wave, and heart rhythm. Finally, we discuss the potential benefits of continuing health monitoring in vascular disease treatment and the challenges of integrating it into clinical settings.
1 February 2025 in International Journal of Electrical and Computer Engineering (IJECE)
Applications of terahertz (THz) imaging technologies have advanced significantly in the disciplines of biology, medical diagnostics, and non- destructive testing in the past several decades. Significant progress has been made in THz biomedical imaging, allowing for the label-free diagnosis of malignant tumors. Terahertz frequencies, which lie between those of the microwave and infrared, are highly sensitive to water concentration and are significantly muted by water. Terahertz radiation does not cause ionization of biological tissues because of its low photon energy. Recently, terahertz spectra, including spectroscopic investigations of cancer, have been reported at an increasing rate due to the growing interest in their biological applications sparked by these unique features. To improve cancer diagnosis with terahertz imaging, an appropriate differentiation technique is required to increased blood supply and localized rise in tissue water content that commonly accompany the presence of malignancy. Terahertz imaging has been found to benefit from structural alterations in afflicted tissues. This study provides an overview of terahertz technology and briefly discusses the use of terahertz imaging techniques in the detection of skin cancer. Research into the promise and perils of terahertz imaging will also be discussed.
19 April 2022 in Advances in Pharmacological and Pharmaceutical Sciences
Electrospinning enables simple and cost-effective production of polymer nanofibers from different polymer materials. Drug delivery systems are capable of achieving maximum drug treatment benefits by significantly reducing adverse complications. Electrospun nanofibers have recently attracted considerable attention owing to their distinctive properties, including flexibility and biocompatibility. The implementation of functional constituents within nanostructure fibers blends is an effective technique for the administration of a variety of drugs in animal research, broadening the nanofiber capability and reliability. The nanofibrous mesh and its various application purposes are discussed in terms of a summary of recent research, emphasizing the ease of streaming and a large number of combinations of this approach, which could lead to a breakthrough in targeted therapy.
9 February 2022 in Applied Bionics and Biomechanics
Tissue engineering is a relatively new area of research that combines medical, biological, and engineering fundamentals to create tissue-engineered constructs that regenerate, preserve, or slightly increase the functions of tissues. To create mature tissue, the extracellular matrix should be imitated by engineered structures, allow for oxygen and nutrient transmission, and release toxins during tissue repair. Numerous recent studies have been devoted to developing three-dimensional nanostructures for tissue engineering. One of the most effective of these methods is electrospinning. Numerous nanofibrous scaffolds have been constructed over the last few decades for tissue repair and restoration. The current review gives an overview of attempts to construct nanofibrous meshes as tissue-engineered scaffolds for various tissues such as bone, cartilage, cardiovascular, and skin tissues. Also, the current article addresses the recent improvements and difficulties in tissue regeneration using electrospinning.