Protyusha GB

Protyusha GB

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Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 December 2023 in Environmental Pollution
Verified
Journal Article
Closed access
PGProtyusha GB
Protyusha GB
KBKavitha B
Kavitha B
RRR.S Robin
R.S Robin
NANithin A
Nithin A
TIT.R Ineyathendral
T.R Ineyathendral
PRPurvaja R
Purvaja R

1 May 2019 in Journal of Oral and Maxillofacial Pathology
Verified
Journal Article
Open access
PDF file
BSB Sivapathasundharam
B Sivapathasundharam
PGProtyusha GB
Protyusha GB
SPS Preethi
S Preethi
Classification is the process of grouping similar entities under one category for the ease of their comprehension and better handling. Medical classification dates back to the days of William Farr who is credited with the development of a nosology, which later served as the forerunner for the modern-day disease classification by ICD. The WHO system of classification is a time-honoured system that has prevailed from decades together and is under constant evolution. The classification of odontogenic tumours was first formulated by Pierre Paul Broca and has undergone several transformations over years. Though the earlier classifications and their modifications by several authors and even by the WHO appeared to be fitting for their time, the latest edition of WHO classification of odontogenic and maxillofacial bone tumours neither seems to be complete nor perfect, even at the present context. It is unfortunate that even with the advancement of molecular biology, the present WHO classification on Odontogenic and Maxillofacial bone tumours, fails to serve as a ‘reference standard’ in the true sense of the term. This article highlights the limitations of the current classification with constructive criticism that may help in further improvement.

14 July 2023 in Dentistry Journal
Verified
Journal Article
Open access
PDF file
PGProtyusha GB
Protyusha GB
AMAnusha Mohan
Anusha Mohan
Eswar KandaswamyEswar Kandaswamy
Eswar Kandaswamy
The aim of this systematic review is to report the treatment options (Intervention) and outcomes (O) for primary teeth affected by periodontitis (Population) and if the treatment of primary teeth can prevent the spread of periodontitis to permanent teeth (Outcomes). The following databases were searched for papers published before December 2022: PubMed, Embase, Web of Science, and Ebscohost. Studies on children affected by periodontitis involving the primary teeth were included and those on children who presented with periodontitis as a manifestation of systemic disease were excluded. Narrative synthesis and methodological quality assessments were performed for the included studies. Three interventional studies (without a control group) that evaluated treatments involving scaling and root planing (SRP with antibiotics) and extraction were included (total n = 60 patients). Additionally, twelve case reports/case series articles (n = 19 patients) were identified. The diagnoses ranged from aggressive periodontitis to juvenile periodontitis and pre-pubertal periodontitis. Based on a limited number of published studies, it was found that the early treatment of periodontitis affecting the primary teeth using SRP and systemic antibiotics resulted in favorable improvements in PD and CAL. Limited evidence suggests that SRP and the extraction of the primary teeth involved have the potential to prevent periodontitis affecting permanent teeth. Future trials are required to standardize the treatment protocols and to confirm these findings.

1 January 2021 in Indian Journal of Dental Research
Verified
Journal Article
Closed access
PGProtyusha GB
Protyusha GB
BSB Sivapatha Sundharam
B Sivapatha Sundharam
Background: The influence of environmental factors on dental caries is a well-established fact; however, little is known about the impact of genetics on the caries process. Aims: This study was aimed to analyse the association between the vitamin D receptor (VDR) gene polymorphism and dental caries. It also compared the risk of dental caries between individuals with homozygous (tt and TT) genotype and heterozygous (Tt) genotype. Further, this study also aimed to compare VDR gene polymorphism by gender. Methodology: A total of 196 subjects were selected based on their decayed, missing, filled teeth (DMFT) index according to the WHO guidelines (1997), and were divided into two groups based on caries experience. The case group was further classified into low and high caries groups. The saliva samples were collected, DNA was extracted, and VDR Taq1 (T/C) gene polymorphism was analysed by polymerase chain reaction–based restriction fragment length polymorphism (PCR-RFLP) and visualized under 2% agarose gel. Results: There was no significant difference in the VDR Taq1 polymorphism and dental caries between the case and control group. However, further stratification showed a statistically significant difference based on caries experience in the study group. The heterozygous mutant genotype (Tt) was associated with a higher caries experience (62.1%) (P = 0.008) with the frequency of ‘t’ allele being 77% as compared to ‘T’ allele (63.6%) in the high caries group. Conclusion: VDR Taq1 gene polymorphism does not seem to have a role in the incidence of dental caries in the studied population; however, it may have a role in the severity of the caries process.

1 July 2021 in Journal of Cancer Research and Therapeutics
Verified
Journal Article
Closed access
PGProtyusha GB
Protyusha GB
BSB. Sivapathasundharam
B. Sivapathasundharam
Basaloid squamous cell carcinoma (BSCC) is a rare, unique, and aggressive variant of squamous cell carcinoma which mostly occurs in the upper aerodigestive tract. Histologically and immunologically different from conventional squamous cell carcinoma, it is mostly seen in men of the sixth and seventh decades and is commonly associated with tobacco and alcohol usage. BSCC usually presents as a high stage disease with distant metastasis, high recurrence rate, and poor prognosis. In the head-and-neck region, BSCC has a strong predilection for sites such as the base of the tongue, soft palate, and epiglottis. Less commonly, it may also occur on the floor of the mouth, gingiva, and tonsils. In the present article, we report a case of BSCC in the right maxillary anterior gingiva of a 57-year-old female for its rarity.

1 January 2020 in Medical Archives
Verified
Journal Article
Closed access
KPKaushik Prakash
Kaushik Prakash
PGProtyusha GB
Protyusha GB
MPManoj Prabhakar
Manoj Prabhakar
SSShanmugapriya S
Shanmugapriya S
Allergic reactions can manifest in various forms ranging from mild, almost unnoticeable reactions to life threatening anaphylaxis. Stomatitis venenata or contact stomatitis is described as a contact allergy of the oral mucosa which can occur due to repeated contact with the causative agent. Dental and cosmetic products, dental materials and dental therapeutic agents are the common allergens of the oral cavity. These allergies show varied clinical presentations, from swelling, pain, burning sensations to vesiculation, ulcerations, crusting and sloughing. Contact stomatitis due to cosmetic products have been on a rise recently due to the ease of availability and increase in their usage among individuals. The aim of this article is to present a case reports on an allergic reaction in a 17-year-old female triggered by the use of cosmetics. In the present article, we report a case of stomatitis venenata due to lip balm in a 17-year-old female for its rarity. Stomatitis venenata is a rare allergic condition that causes significant morbidity in an affected individual. Prompt recognition and elimination of the causative allergen followed by an appropriate therapy would help in complete resolution of this condition.