Marco Antonio de Andrade Belo

Prof. Dr. Marco Antonio de Andrade Belo


Research Focus & Metrics

Academic Career Length

22Years (2005-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 March 2019 in Scientific Reports
Verified
Journal Article
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ICIves Charlie-Silva
Ives Charlie-Silva
AKAndre Klein
Andre Klein
JGJuliana M. M. Gomes
Juliana M. M. Gomes
EPEd J. R. Prado
Ed J. R. Prado
AMAlessandra C. Moraes
Alessandra C. Moraes
MBMarco Antonio de Andrade Belo
Marco Antonio de Andrade Belo
Acute-phase protein (APPs) serum levels have been studied in many human diseases, and their components contribute to host defense during the evolution of infectious diseases by acting as part of the innate immune system. Based on the importance of establishing new experimental models, the present investigation evaluated the modulation of APPs following inflammatory stimulus by the inoculation ofAeromonas hydrophilain tilapias. Fish were sampled 6 and 24 hours post-infection. Tilapias presented increase of positive APPs such as ceruloplasmin, haptoglobin, alpha-2-macroglobulin and complement C3, as well as decrease of negative APPs such as albumin and transferrin. The protein response of tilapias during the course of bacterial infection showed correlation with the kinetics of cellular accumulation in the inflamed focus with significant increase of granulocytes, thrombocytes, lymphocytes and macrophages. However, granulocytes were the predominant cells, associated with increment in the reactive oxygen species (ROS) production. Showing responses similar to those observed in humans, the modulation of APPs and the kinetics of cellular accumulation in the exudate demonstrate the feasibility of this alternative experimental model for advances and studies to understand changes in pathophysiological mechanisms of acute inflammatory reaction due to bacterial infection.

23 December 2009 in Aquaculture
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Journal Article
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VRValeska Regina Reque
Valeska Regina Reque
JMJulieta Rodini Engrácia De Moraes
Julieta Rodini Engrácia De Moraes
MBMarco Antonio de Andrade Belo
Marco Antonio de Andrade Belo
FMFlávio Ruas de Moraes
Flávio Ruas de Moraes

1 July 2012 in Pesquisa Agropecuária Brasileira
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Journal Article
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MBMarco Antonio de Andrade Belo
Marco Antonio de Andrade Belo
JMJulieta Rodini Engrácia De Moraes
Julieta Rodini Engrácia De Moraes
VSVando Edésio Soares
Vando Edésio Soares
MMMaurício Laterça Martins
Maurício Laterça Martins
CBCamila Dantas Brum
Camila Dantas Brum
FMFlávio Ruas de Moraes
Flávio Ruas de Moraes
The objective of this work was to evaluate the effect of food supplementation with vitamin C on macrophage and multinucleated giant cell (MGC) activities of pacus at two stocking densities. The experiment was carried out in a 2x2x3 split-plot factorial arrangement with: 0 and 500 mg kg-1 vitamin C; 5 and 20 kg m-3 stocking densities; and evaluation times at 3, 6, and 12 days after the subcutaneous implantation of glass coverslips (DPI). The number of macrophages and MGC, as well as cortisol and glucose plasma levels were determined. The number of macrophages and MGC with two to five nuclei was significantly greater in fish supplemented with vitamin C at 5 kg m-3 stocking density at 3 DPI in comparison to nonsupplemented ones. The macrophage and MGC counts were lower in fish with high-plasma cortisol concentration. Supplementation with 500 mg vitamin C benefits macrophage activity on foreign-body inflammation, and high-cortisol concentration has suppressive effects on this response.

18 December 2013 in Bulletin of Environmental Contamination and Toxicology
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MCMarcello Pardi Castro
Marcello Pardi Castro
FMFlávio Ruas de Moraes
Flávio Ruas de Moraes
RFRodrigo Yudi Fujimoto
Rodrigo Yudi Fujimoto
CCClaudinei da Cruz
Claudinei da Cruz
MBMarco Antonio de Andrade Belo
Marco Antonio de Andrade Belo
JMJulieta Rodini Engrácia De Moraes
Julieta Rodini Engrácia De Moraes
This study evaluated the toxicity of hexavalent and trivalent compounds of chromium to the pacu, Piaractus mesopotamicus, in acute exposures of 96 h through mortality and histopathological responses. Hexavalent potassium dichromate was more toxic than trivalent compounds of chromium chloride, chromium oxide and chromium carbochelate. Sufficient mortalities occurred only with potassium dichromate to yield an LC50 value at 124.2 mg L−1. Hexavalent chromium caused reversible and irreversible lesions, which may affect organ functionality. Histopathological evaluation showed that trivalent chromium caused lesions of lower severity. Pacu subjected to different concentrations of chromium carbochelate showed no histopathological changes in the kidneys, liver, skin and gills, being similar to those of the control fish. Among the three sources of Cr3+, only chromium chloride at 200 mg L−1 resulted in mortality, which reached 100 % within the first 18 h. These findings confirm that trivalent chromium, when administered within recommended levels, may be used safely in aquaculture.

1 June 2020 in Fish & Shellfish Immunology
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Journal Article
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TFThais Heloisa Vaz Farias
Thais Heloisa Vaz Farias
SASalvador Arijo
Salvador Arijo
AMAlberto Medina
Alberto Medina
GPGabriela Pala
Gabriela Pala
EPEd Jhonny da Rosa Prado
Ed Jhonny da Rosa Prado
MBMarco Antonio de Andrade Belo
Marco Antonio de Andrade Belo

1 December 2019 in Fish & Shellfish Immunology
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Journal Article
Closed access
WMWILSON GOMEZ MANRIQUE
WILSON GOMEZ MANRIQUE
MFMayra Araguaia Pereira Figueiredo
Mayra Araguaia Pereira Figueiredo
ICIves Charlie-Silva
Ives Charlie-Silva
MBMarco Antonio de Andrade Belo
Marco Antonio de Andrade Belo
CDCristina Corsi Dib
Cristina Corsi Dib