The challenge for enterprises to enter the market in the bottom of the pyramid (BOP) segment is to revise their supply chain design. This article compiles the cases that demonstrate how enterprises can successfully enter BOP markets. Factors are extracted and analyzed according to the stages of the value chain and the supply chain. Furthermore, the Importance—Performance Analysis (IPA) is used to explore the gap and the opportunities for improvement. Also, the multinational enterprises (MNEs) in Taiwan and local manufacturers in Indonesia are compared for their suitability to the different business strategies. Results of these analyses could serve as a gap analysis tool for decision-making and business strategies entering the BOP market.