In this paper, we develop a deterministic mathematical epidemic model for tuberculosis outbreaks in order to study the disease’s impact in a given population. We develop a qualitative analysis of the model by showing that the solution of the model is positive and bounded. The global stability analysis of the model uses Lyapunov functions and the threshold quantity of the model, which is the basic reproduction number is estimated. The existence and uniqueness analysis for Caputo fractional tuberculosis outbreak model is presented by transforming the deterministic model to a Caputo sense model. The deterministic model is used to predict real data from Uganda and Rwanda to see how well our model captured the dynamics of the disease in the countries considered. Furthermore, the sensitivity analysis of the parameters according to $R_0$ was considered in this study. The normalised forward sensitivity index is used to determine the most sensitive variables that are important for infection control. We simulate the Caputo fractional tuberculosis outbreak model using the Adams–Bashforth–Moulton approach to investigate the impact of treatment and vaccine rates, as well as the disease trajectory. Overall, our findings imply that increasing vaccination and especially treatment availability for infected people can reduce the prevalence and burden of tuberculosis on the human population.

The rising tide of smoking-related diseases has irreparably damaged the health of both young and old people, according to the World Health Organization. This study explores the dynamics of the age-structure smoking model under fractal-fractional (F-F) derivatives with government intervention coverage. We present a new fractal-fractional model for two-age structure smokers in the Caputo–Fabrizio framework to emphasize the potential of this operator. For the existence-uniqueness criterion of the given model, successive iterative sequences are defined with limit points that are the solutions of our proposed age-structure smoking model. We also use the functional technique to demonstrate the proposed model stability under the Ulam–Hyers condition. The two age-structure smoking models are numerically characterized using the Newton polynomial. We observe that in Groups 1 and 2, a change in the fractal-fractional orders has a direct effect on the dynamics of the smoking epidemic. Moreover, testing the inherent effectiveness of government interventions shows a considerable impact on potential, occasional, and temporary smokers when the fractal-fractional order is 0.95. It is the view that this study will contribute to the applicability of the schemes, the rich dynamics of the fractal, and the fractional perspective of future predictions.