A slight improvement in the transmission efficiency of the herringbone star gear train in a GTF has a great impact on the fuel economy of the engine. Here, the influencing factors of gear train efficiency were studied from the perspective of gear train composition, and the efficiency calculation model of the split star gear train, including the load-sharing coefficient, was established. Based on the efficiency calculation model, the mechanical relationship affecting the load distribution of the split star gear train, and the influence of installation error on the power split of the gear train, were studied. The effects of torque and installation error on the load coefficient of the gear train were studied using dynamic analysis software, and the efficiency of the gear train under multiple working conditions was verified and analyzed.
To date, few studies have been conducted on the characteristics of flow and dispersion caused by indoor radiant floor heating integrated with natural ventilation. In this study, we employed reduced−scale numerical models validated by wind−tunnel experiments to investigate the influence of radiant floor heating integrated with natural ventilation on airflow, heat transfer, and pollutant dispersion within an isolated building. The Richardson number (Ri) was specified to characterize the interaction between the inflow inertia force and the buoyancy force caused by radiant floor heating. Several Ri cases from 0 to 26.65, coupled with cross− or single−sided ventilation, were considered. Model validation showed that the numerical model coupled with the RNG k-ε model was able to better predict the indoor buoyant flow and pollutant dispersion. The results showed that the similarity criterion of Ri equality should be first satisfied in order to study indoor mixed convection using the reduced−scale model, followed by Re−independence. For cross−ventilation, when Ri < 5.31, the incoming flow inertia force mainly dominates the indoor flow structure so that the ACH, indoor temperature, and pollutant distributions remain almost constant. When Ri > 5.31, the thermal buoyancy force becomes increasingly important, causing significant changes in indoor flow structures. However, for single−sided ventilation, when Ri > 5.31 and continues to increase, the buoyancy force mainly dominates the indoor flow structure, causing a significant increase in ACH, thus reducing the indoor average temperature and pollutant accumulation.
We prepared a tumor microenvironment-responsive magnetic nanofluid (MNF) for improving tumor targeting, imaging and treatment simultaneously. For this purpose, we synthesized sulfonamide-based amphiphilic copolymers with a suitable pKa at 7.0; then, we utilized them to prepare the tumor microenvironment-responsive MNF by self-assembly of the sulfonamide-based amphiphilic copolymers and hydrophobic monodispersed Fe3O4 nanoparticles at approximately 8 nm. After a series of characterizations, the MNF showed excellent application potential due to the fact of its high stability under physiological conditions and its hypersensitivity toward tumor stroma by forming aggregations within neutral or weak acidic environments. Due to the fact of its tumor microenvironment-responsiveness, the MNF showed great potential for accumulation in tumors, which could enhance MNF-mediated magnetic resonance imaging (MRI), magnetic hyperthermia (MH) and Fenton reaction (FR) in tumor. Moreover, in vitro cell experiment did not only show high biocompatibility of tumor microenvironment-responsive MNF in physiological environment, but also exhibit high efficacy on inhibiting cell proliferation by MH-dependent chemodynamic therapy (CDT), because CDT was triggered and promoted efficiently by MH with increasing strength of alternating magnetic field. Although the current research is limited to in vitro study, these positive results still suggest the great potential of the MNF on effective targeting, diagnosis, and therapy of tumor.