Costin Iulian Lupu

Dr. Costin Iulian Lupu

Public Health, UMF Grigore T Popa Iasi, Iaşi, Romania

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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28 November 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
ZSZinovia Ioan Surlari
Zinovia Ioan Surlari
Dana gabriela BudalaDana gabriela Budala
Dana gabriela Budala
CLCostin Iulian Lupu
Costin Iulian Lupu
CSCarmen Gabriela Stelea
Carmen Gabriela Stelea
Oana Maria ButnaruOana Maria Butnaru
Oana Maria Butnaru
Ionut LuchianIonut Luchian
Ionut Luchian
The concept of machines learning and acting like humans is what is meant by the phrase “artificial intelligence” (AI). Several branches of dentistry are increasingly relying on artificial intelligence (AI) tools. The literature usually focuses on AI models. These AI models have been used to detect and diagnose a wide range of conditions, including, but not limited to, dental caries, vertical root fractures, apical lesions, diseases of the salivary glands, maxillary sinusitis, maxillofacial cysts, cervical lymph node metastasis, osteoporosis, cancerous lesions, alveolar bone loss, the need for orthodontic extractions or treatments, cephalometric analysis, age and gender determination, and more. The primary contemporary applications of AI in the dental field are in undergraduate teaching and research. Before these methods can be used in everyday dentistry, however, the underlying technology and user interfaces need to be refined.

6 September 2022 in Medicina
Verified
Journal Article
Open access
PDF file
Elena-Raluca BaciuElena-Raluca Baciu
Elena-Raluca Baciu
Dana gabriela BudalaDana gabriela Budala
Dana gabriela Budala
RVRoxana-Ionela Vasluianu
Roxana-Ionela Vasluianu
CLCostin Iulian Lupu
Costin Iulian Lupu
MMmurariu_alice MURARIU
murariu_alice MURARIU
Ionut LuchianIonut Luchian
Ionut Luchian
Background and Objectives: Study models are essential tools used in the dental teaching process. The aim of the present study was to compare the values obtained by manual and digital orthodontic measurements on physical and digital case study models. Materials and Methods: The physical experimental models were obtained by traditional pouring (improved stone-type IV gypsum products) and by additive manufacturing (resins). The digital experimental models were created by scanning the physical ones, using a white light-emitting diode (LED) source and an L-shaped dental scanner—Swing DOF (DOF, Seoul, Korea). The physical study models were first measured using a digital caliper, and then, they were scanned and evaluated using the DentalCad 3.0 Galway software (exocad GmbH, Darmstadt, Germany). The Pont, Linder–Harth, and Bolton indices, which are used in orthodontics for training students, were derived using the available data. Results: When comparing the linear measurement mean ranks taken on physical study models to those of digital models, no statistically significant differences (p > 0.05) were found. A similar result was also shown when the dentoalveolar growth indicators were analyzed. Conclusions: It can be concluded that dental study models made by direct light processing (DLP) and pouring type IV class gypsum are both acceptable for orthodontic teaching purposes.

18 July 2023 in Medicina
Verified
Journal Article
Open access
PDF file
Dana gabriela BudalaDana gabriela Budala
Dana gabriela Budala
CLCostin Iulian Lupu
Costin Iulian Lupu
RVRoxana-Ionela Vasluianu
Roxana-Ionela Vasluianu
NINicoleta Ioanid
Nicoleta Ioanid
Oana Maria ButnaruOana Maria Butnaru
Oana Maria Butnaru
Elena-Raluca BaciuElena-Raluca Baciu
Elena-Raluca Baciu
Background and Objectives: Learning to speak properly requires a fully formed brain, good eyesight, and a functioning auditory system. Defective phonation is the outcome of a failure in the development of any of the systems or components involved in speech production. Dentures with strong phonetic skills can be fabricated with the help of a dentist who has a firm grasp of speech production and phonetic characteristics. Every dentist strives to perfect their craft by perfecting the balance between the technical, cosmetic, and acoustic aspects of dentistry, or “phonetics”. The ideal prosthesis for a patient is one that not only sounds good but also functions well mechanically and aesthetically. Words are spoken by using articulators that alter their size and form. Conclusions: Therefore, a prosthesis should be made in such a way that it does not interfere with the ability to communicate. As a result, a prosthodontist has to have a solid grasp of how speech is made and the numerous parts that go into it.

16 March 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
Dana gabriela BudalaDana gabriela Budala
Dana gabriela Budala
CBCarina Balcoş
Carina Balcoş
AAAdina Oana Armencia
Adina Oana Armencia
DVDragoș Ioan Virvescu
Dragoș Ioan Virvescu
CLCostin Iulian Lupu
Costin Iulian Lupu
Ionut LuchianIonut Luchian
Ionut Luchian
Significant changes in the microstructure of the brain cause dementia and other mental declines associated with aging and disease. Although research has established a connection between oral health and dementia, the underlying pathologic mechanisms are still unknown. Aim: Our aim was to evaluate dentures’ impact on the cognitive state of geriatric patients. Material and methods: A total of 108 individuals seeking treatment at the Faculty of Dental Medicine in Iasi, Romania, participated in the study, which ran from May 2022 to October 2022. Cognitive dysfunction was assessed using the Mini-Mental State Examination. The acquired data were analyzed with IBM SPSS 26.0, and the p-value was set at 0.05. Results: The average value of the MMSE score was 21.81 ± 3.872. Differences between groups of wearer/non-wearer subjects were statistically significant for most of the questions in the questionnaire. Linear regression analysis showed that individuals with a high MMSE score have prosthodontic treatment. A decrease in the MMSE score is associated with a decrease in masticatory efficiency (B = 1.513, p = 0.268). Conclusions: This study provides further evidence that tooth loss is associated with worse cognitive performance. It is thus conceivable that the necessary effects can be achieved by increasing the efforts dedicated to preventing tooth loss in the adult population.

19 September 2025 in Biomimetics
Verified
Journal Article
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CLCostin Iulian Lupu
Costin Iulian Lupu
MTMonica Silvia Tatarciuc
Monica Silvia Tatarciuc
AVAnca-Mihaela Vitalariu
Anca-Mihaela Vitalariu
LBLivia Ionela Bobu
Livia Ionela Bobu
DPDiana Antonela Diaconu Popa
Diana Antonela Diaconu Popa
ADAna Maria Dima
Ana Maria Dima
Zirconia’s superior mechanical properties and biocompatibility have made it a cornerstone of modern prosthodontics, yet achieving durable biomimetic bonding to tooth structure remains a challenge. This scoping review synthesizes evidence on bonding strategies for zirconia-based fixed dental prostheses (FDPs), evaluating surface treatments, cementation protocols, and long-term performance. Following PRISMA-ScR guidelines, 18 studies from PubMed, Scopus, Web of Science, and Embase were thoroughly analyzed. Key findings indicate that tribochemical silica coating (e.g., Rocatec™) combined with 10-methacryloyloxydecyl dihydrogen phosphate (MDP)-based primers (e.g., Panavia V5) is associated with the highest bond strengths (>40 MPa) and exceptional clinical survival rates (e.g., >95% at 15 years for resin-bonded FDPs). These combined mechanical–chemical strategies can be viewed as an attempt to create a biomimetic, hybrid interface akin to the natural enamel–dentin junction. Additively manufactured zirconia exhibits inferior bonding compared to milled counterparts, while ethyl cellulose coatings applied to the bonding surface effectively prevent contamination from saliva and moisture during intraoral try-in procedures. However, heterogeneous testing protocols and limited long-term clinical data highlight the need for standardized aging models and randomized trials. This review consolidates current evidence, offering clinically actionable recommendations through a biomimetic lens while identifying critical gaps for future research.

1 May 2024 in Healthcare
Verified
Journal Article
Open access
PDF file
STSilviu Catalin Tibeica
Silviu Catalin Tibeica
Elena-Raluca BaciuElena-Raluca Baciu
Elena-Raluca Baciu
CLCostin Iulian Lupu
Costin Iulian Lupu
CBCarina Balcoş
Carina Balcoş
Ionut LuchianIonut Luchian
Ionut Luchian
ECElena Cărăuşu
Elena Cărăuşu
Background and Objectives: Questionnaires designed to test knowledge and self-perception can be valuable tools for diagnosing a dentist’s understanding of the management and administration of a practice. The objective of this study was to create and authenticate a questionnaire for assessing dentists’ self-perception on oral healthcare management developed from discussions with experts in this field. Material and Methods: In order to create and verify a questionnaire survey, a cross-sectional, descriptive, and analytical study was carried out. Participants’ personal information and 31 statements across four categories made up the final questionnaire form. The answers to the questionnaire were in the form of a Likert scale. After refining the initial version, a total of 36 interviews were conducted at dental offices to verify the validity. For the Exploratory Factor Analysis (EFA), we used the Kaiser–Meyer–Olkin (KMO) index, the Bartlett sphericity test, and also Cronbach alpha coefficient for the validity of the questionnaire. Results: The accuracy of the instrument was measured by intrarater and interrater reliability. For the EFA, all the communalities exceeded the threshold of 0.05. With a Cronbach’s alpha coefficient of 0.898, the questionnaire has sufficient internal consistency. Conclusions: The questionnaire demonstrates robust reliability and validity, thereby affirming its suitability for its intended purpose.