Introduction: A retrospective review was performed for patients in the Veterans Administration Healthcare System who underwent prophylactic stabilization of the femur for metastatic disease. The goal was to evaluate indications for prophylactic stabilization through Mirels criteria. Methods: All veterans who underwent inpatient prophylactic femoral stabilization between October 2010 and September 2015 were identified. Procedure and demographic variables were collected by using chart review. Provider notes and radiographs were reviewed to calculate Mirels scores. Results: Ninety-two patients underwent confirmed prophylactic stabilization for metastatic bone disease. Lung cancer and multiple myeloma accounted for most lesions. The mean Mirels score was 10.3 (range 7 to 12). 3.2% of patients had a score of 7, and 6.5% had a score of 8. Most lesions were peritrochanteric (66%) and lytic (85%). There was more variability in size (mean 2.3), with 15% being under one third of bony width and 38% between one and two-thirds. The mean pain score was 2.5; 73% reported functional pain. Of lytic and peritrochanteric lesions (53% of all cases), 55% were less than two-thirds the cortical width and 31% lacked functional pain. Conclusion: This retrospective study of prophylactically stabilized metastatic lesions revealed that more than 90% of patients had Mirels scores greater than 8, suggesting a substantial risk of pathologic fracture. Over half of all stabilized lesions were peritrochanteric and lytic. These criteria alone achieve a minimum Mirels score of 8; however, one-third of these lacked functional pain. Notably, Mirels' original paper found location and type criteria to be the least predictive of impending fracture. Contrariwise, functional pain was the most accurate predictor. Multiple studies have found poor specificity of the Mirels criteria. The high scores achievable by the location and type criteria may represent an overrepresentation of their contribution to fracture risk. Reconsideration of the relative weights of each criterion warrants further examination.
Metastatic bony disease is a significant health issue, with approximately 700,000 new cases annually that tend to metastasize to bones. The proximal femur in the appendicular skeleton is commonly affected. Our study aimed to investigate mortality rates and hospital stay duration in patients with pathologic proximal femur fractures treated with either intramedullary nailing or arthroplasty within the Veterans Health Administration system. In total, 679 patients (265 arthroplasty, 414 intramedullary nails) were identified through ICD-9 and CPT codes from 30 September 2010 to 1 October 2015. Hospital stays were similar for both groups (arthroplasty: 10.5 days, intramedullary nails: 11 days, p = 0.1). Mortality was associated with increased age and Gagne comorbidity scores (p < 0.001). Arthroplasty showed a survival benefit in the log-rank test (p = 0.018), and this difference persisted in the multivariate analysis after adjusting for age and comorbidities, with a hazard ratio of 1.3. Our study reported evidence that arthroplasty is associated with increased patient survival even when accounting for age and comorbidities in treating metastatic disease of the proximal femur.
14 October 2025 in Techniques in Hand & Upper Extremity Surgery
Arthritis of the thumb carpometacarpal (CMC) joint is common, with an estimated radiographic prevalence of 10.9% and 13.7% of 60-year-old males and females, respectively. Approximately 15% of symptomatic patients will go on to surgery after failing conservative management. Multiple procedures have proven effective for the treatment of thumb CMC arthritis, each with different risks and benefits regarding morbidity, recovery time, and cost. While trapeziectomy with ligament reconstruction and tendon interposition is the most common surgical technique in the United States for thumb CMC arthritis, the optimal operative management remains inconclusive. Trapeziectomy with suture button suspensionplasty (Arthrex, Mini TightRope) has gained popularity in recent years as a new method for treating thumb CMC arthritis. By obviating the need for Kirschner wire fixation or tendon autograft, morbidity is spared, and earlier initiation of occupational therapy and motion is achievable. However, suture button techniques require fluoroscopy and expensive implants, which may require removal due to prominence. We present a novel, more economical alternative to the commercially available suture button suspensionplasty, which can be performed without fluoroscopy and with readily available suture (#2 Orthocord). This procedure has been performed as a primary reconstruction in 80 hands since 2016 with a 2.5% (2/80) reoperation rate and high patient satisfaction.