Journal of Clinical and Diagnostic Research aims to publish findings of doctors at grass root level and post graduate students, so that all unique medical experiences are recorded in literature.

Introduction. Depression is one of the four major diseases in the world and is the most common cause of disability from diseases. The aim of this study is to estimate the prevalence of depression among Iranian university students using meta-analysis method.Materials and Methods. Keyword depression was searched in electronic databases such as PubMed, Scopus, MAGIran, Medlib, and SID. Data was analyzed using meta-analysis (random-effects model). Heterogeneity of studies was assessed using theI2index. Data was analyzed using STATA software Ver.10.Results. In 35 studies conducted in Iran from 1995 to 2012 with sample size of 9743, prevalence of depression in the university students was estimated to be 33% (95% CI: 32–34). The prevalence of depression among boys was estimated to be 28% (95% CI: 26–30), among girls 23% (95% CI: 22–24), single students 39% (95% CI: 37–41), and married students 20% (95% CI: 17–24). Metaregression model showed that the trend of depression among Iranian students was flat.Conclusions. On the whole, depression is common in university students with no preponderance between males and females and in single students is higher than married ones.

Background: Personality traits can be used to predict an individual’s behaviors in different life situations, including marital life situations. Marital satisfaction that is influenced by different factors is a criterion used to assess couples’ relationship quality. The goal of the present study was to review Iranian studies on the correlation between personality traits and marital satisfaction.Methods: In this systematic review, all the related Iranian studies in international databases, including Google Scholar, PubMed, Web of Science (ISI) and Scopus, and national databases, including Scientific Information Database (SID) and MagIran were reviewed. The following keywords and also combinations of them were used to search the databases: “Marital satisfaction,” “Personality traits,” “Personality factors,” “Big five model of personality,” and “Iran.”Results: A total of 18 correlational studies, without any time limitation, with a total sample of 4049, were reviewed. The following correlation coefficients were found between marital satisfaction and personality traits: r = − 0.439 with neuroticism (95% Confidence Interval [CI]: 0.27–0.60), r = 0.833 with extraversion (95% CI: 0.77–0.88), r = 0.777 with openness (95% CI: 0.70–0.84), r = 0.855 with agreeableness (95% CI: 0.80–0.90), and r = 0.90 with conscientiousness (95% CI: 0.84–0.95).Conclusions: Couples high in Neuroticism experience lower levels of marital satisfaction, and couples high in Conscientiousness are more satisfied with their marital life.

Context: Several studies have been conducted on the relationship between depression and metabolic syndrome, which have had conflicting results. The purpose of this study was a meta-analysis of studies that have examined the relationship between these two variables. Evidence Acquisition: This meta-analysis systematically reviewed the relationship between depression and metabolic syndrome. Scientific databases including IranMedex, SID, Magiran, Scopus, PubMed, Google Scholar, and Science Direct were searched and 17 articles were extracted from 2000 to 2014. Selected studies data were analyzed using meta-analysis and random effects model. Heterogeneity between the studies was examined using I2. Data were analyzed using STATA software version 12.1. Results: Seventeen studies were analyzed with a sample size of 31880 people. Analysis by the type of studies showed that the relationship between the two variables in cross-sectional studies (OR = 1.51, CI 95% = 1.36 - 1.68) and cohort studies (OR = 1.6, CI 95% = 1.23 - 2.08) was significant. In general, the heterogeneity test results among the studies was not significant (P for heterogeneity = 0.08, I² = 39.8%). Conclusions: There is a relationship between depression and metabolic syndrome. Keywords: Meta-Analysis; Depression; Metabolic Syndrome

Background: Suicide, a social phenomenon, is a major health problem in most countries. Yet data relating to the role social factors play in the development of this condition are lacking, with some factors shrouded in greater ambiguity than others. As such, this review aimed to determine the prevalence of social-related factors resulting in suicide and to present these findings through meta-analyses, allowing for causes of heterogeneity to be examined. Methods: Scientific databases including PubMed and Science direct were searched using sensitive keywords. Two researchers reviewed the eligibility of studies and extracted data. Meta-regression with the Mantel-Haenszel method was conducted using a random effect model, in addition to subgroup analysis and Egger’s test. Results: A total of 2,526 articles were retrieved through the initial search strategy, producing 20 studies from 16 provinces for analysis. The most frequent cause of attempted suicide among the 20 analyzed articles was family conflict with 32% (95% CI: 26–38). Other related factors included marital problems (26%; 95% CI: 20–33), economic constrains (12%; 95% CI: 8–15) and educational failures (5%; 95% CI: 3–8). Results of meta-regression analysis found that sample size significantly affects heterogeneity for the factor ‘family conflict’. Conclusions: Social factors such as family conflicts and marital problems have a noticeable role in Iranian suicidology.

Infant low birth weight is one of the major problems in different societies. Different reports have provided different results regarding the relationship between maternal anemia and infant low birth weight in different months of pregnancy. The aim of this study was to determine the relationship between maternal anemia during pregnancy and infant low birth weight. This systematic review was conducted using related keywords in national (Sid, Iran.doc, Iran medex and Magiran) and international (PubMed, Science Direct, Cochrane, Medline, Web of Science, Scopus, Springer, Embase, Google scholar) databases. Relative risks and confidence intervals were extracted from each study. The results were combined using random-effects model for meta-analysis. The I² index was also used to measure heterogeneity between the studies. Overall, 17 studies with a total sample size of 245407 entered the final meta-analysis and demonstrated that the relative risk for maternal anemia in the first, second and third trimester of pregnancy were 1.26 (95% CI: 1.03-1.55), 0.97 (95% CI: 0.57-1.65), and 1.21 (95% CI: 0.84-1.76), respectively. The relationship between maternal anemia and infant low birth weight in the first trimester of pregnancy was significant. Maternal anemia, especially during the first trimester of pregnancy, can be considered as a risk factor for pregnancy outcomes. Therefore, one needs to take the necessary steps to cure this disease in order to reduce the incidence of infant low birth weight.