Pedro Bretcha-Boix

Dr. Pedro Bretcha-Boix

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Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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24 August 2022 in Cancers
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Journal Article
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PMPaula Munoz
Paula Munoz
PBPedro Bretcha-Boix
Pedro Bretcha-Boix
VAVicente Artigas
Vicente Artigas
JAJosé Manuel Asencio
José Manuel Asencio
Surgery is the key treatment in retroperitoneal sarcoma (RPS), as completeness of resection is the most important prognostic factor related to treatment. Compartmental surgery/frontline extended approach is based on soft-tissue sarcoma surgical principles, and involves resecting adjacent viscera to achieve a wide negative margin. This extended approach is associated with improved local control and survival. This surgery must be tailored to tumor histology, tumor localization, and patient performance status. We herein present a review of compartmental surgery principles, covering the oncological and technical basis, and describing the tailored approach to each tumor subtype and localization in the retroperitoneum.
4 January 2024 in Journal of Clinical Medicine
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Journal Article
Open access
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AFAlba Fernández-Candela
Alba Fernández-Candela
PBPedro Bretcha-Boix
Pedro Bretcha-Boix
JRJUAN CARLOS RUIZ RAMIREZ
JUAN CARLOS RUIZ RAMIREZ
APAlejandro Paz
Alejandro Paz
PMPaula Munoz
Paula Munoz
JFJosé Farré-Alegre
José Farré-Alegre
Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have demonstrated their impact on disease-free survival (DFS) and overall survival (OS) of patients with peritoneal metastases (PM). However, prior literature lacks evidence regarding any follow-up beyond 5 years. In this study, we analyse long-term OS and DFS (more than 10 years of follow-up) of patients undergoing CRS + HIPEC in a specialized unit. We conducted a retrospective study that included only patients who underwent CRS + HIPEC from January 2001 to May 2012. Data collection was conducted by reviewing medical records and telephone calls to patients or relatives. A total of 86 patients were included. The mean PCI was nine (range 0–39) and complete cytoreduction (CC-0) was reached in 80% of patients. Postoperative complications Clavien–Dindo III-IV occurred in 27.9% of patients and the 30-day mortality rate was 2.3%. After 10 years of actual follow-up, OS was 33.7% and DFS was 31.4%. Considering the historical context in which the standard of care for patients with PM was palliation, the results obtained show that CRS + HIPEC was a valid option, with morbimortality comparable to other major abdominal surgeries and encouraging survival results, since, after 10 years of follow-up, almost one-third of patients are still alive and disease-free.
16 May 2025
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Journal Article
Open access
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PBPedro Bretcha-Boix
Pedro Bretcha-Boix
MDMarie Stephanie Nunez Duarte
Marie Stephanie Nunez Duarte
ADA Dieter
A Dieter
RSR Silver
R Silver
Introduction: Transanal excision (TAE) is increasingly used to treat malignant polyps and early-stage rectal tumors due to its minimally invasive nature, which facilitates quicker recovery and fewer postoperative complications compared to traditional abdominal approaches. However, while TAE is generally safe, rare complications—such as pneumoperitoneum, pneumoretroperitoneum, and subcutaneous emphysema—can occur, likely related to insufflation pressures during the procedure. Case Report: We report the case of a 72-year-old woman who underwent TAE for a rectal adenocarcinoma. The procedure was completed without evidence of intraoperative perforation. Nonetheless, on postoperative day one, the patient developed respiratory distress, fever, and abdominal discomfort. Imaging studies revealed the presence of air in the retroperitoneum and soft tissues. She was managed conservatively with intravenous antibiotics and supportive care, leading to full recovery by day four without the need for additional surgical intervention. Conclusion: This case underscores that, although TAE offers significant benefits in terms of reduced morbidity, clinicians should remain vigilant for rare but dramatic complications. In the absence of peritonitis or sepsis, conservative management appears effective, supporting the continued use of TAE as a safe and minimally invasive option for rectal tumor excision.