Ajay Malhotra

Dr. Ajay Malhotra

orcid

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2018 in JAMA Neurology
Verified
Journal Article
Open access
PDF file
AMAjay Malhotra
Ajay Malhotra
XWXiao Wu
Xiao Wu
HFHoward P. Forman
Howard P. Forman
CMCharles C. Matouk
Charles C. Matouk
DGDheeraj Gandhi
Dheeraj Gandhi
PSPina Sanelli
Pina Sanelli
Unruptured intracranial aneurysms (UIAs) are relatively common in the general population and are being increasingly diagnosed owing to more frequent use of less invasive imaging techniques and higher resolution of images.1 A large number (≤87.6%) of these incidental UIAs are small, measuring less than 3 to 4 mm.2 Small aneurysms (≤7 mm) uncommonly cause aneurysmal symptoms and are labeled as incidental.3,4 The natural history of UIAs remains poorly understood, and only 0.25% of UIAs eventually rupture, contributing to uncertainty regarding their optimal management.5-7

4 July 2017 in Annals of Internal Medicine
Verified
Journal Article
Closed access
PDF file
AMAjay Malhotra
Ajay Malhotra
XWXiao Wu
Xiao Wu
HFHoward P. Forman
Howard P. Forman
HNHolly K. Grossetta Nardini
Holly K. Grossetta Nardini
CMCharles C. Matouk
Charles C. Matouk
PSPina Sanelli
Pina Sanelli
Small unruptured intracranial aneurysms (UIAs) are increasingly diagnosed. Management depends on growth and rupture risks, which may vary by aneurysm size. To summarize evidence about the growth and rupture risk of UIAs 7 mm and smaller and to explore differences in growth and rupture risks of very small (≤3 mm) and small (≤5 mm) aneurysms. MEDLINE, EMBASE, Scopus, and the Cochrane Library from inception to 2017 (with no language restrictions). Published case series and observational studies that reported natural history data on UIAs 7 mm and smaller. 2 reviewers abstracted study information, evaluated study quality, and graded strength of evidence. Of 26 studies, 5, 10, and 8 described the growth rate of aneurysms 3 mm and smaller, 5 mm and smaller, and 7 mm and smaller, respectively, whereas rupture rates were reported in 7, 11, and 13 studies for aneurysms 3 mm and smaller, 5 mm and smaller, and 7 mm and smaller, respectively. The annualized growth rate was less than 3% in all but 1 study for all 3 size categories. The annualized rupture rate was 0%, less than 0.5%, and less than 1% for the 3 size categories, respectively. Strength of evidence was very low quality for growth rates and low quality for rupture rates. Heterogeneous definitions of growth; heterogeneous and selective treatment and follow-up methods, particularly in high-risk patients. Poor-quality evidence suggests that small UIAs have low growth and rupture rates and very small UIAs have little or no risk for rupture. None.

18 April 2018 in Insights into Imaging
Verified
Journal Article
Open access
PDF file
AMAjay Malhotra
Ajay Malhotra
LTLong Tu
Long Tu
VKVivek B. Kalra
Vivek B. Kalra
XWXiao Wu
Xiao Wu
Ali Y MianAli Y Mian
Ali Y Mian
DGDheeraj Gandhi
Dheeraj Gandhi
Meckel’s cave is a dural recess in the posteromedial portion of the middle cranial fossa that acts as a conduit for the trigeminal nerve between the prepontine cistern and the cavernous sinus, and houses the Gasserian ganglion and proximal rootlets of the trigeminal nerve. It serves as a major pathway in perineural spread of pathologies such as head and neck neoplasms, automatically upstaging tumours, and is a key structure to assess in cases of trigeminal neuralgia. The purpose of this pictorial review is threefold: (1) to review the normal anatomy of Meckel’s cave; (2) to describe imaging findings that identify disease involving Meckel’s cave; (3) to present case examples of trigeminal and non-trigeminal processes affecting Meckel’s cave. • Meckel’s cave contains the trigeminal nerve between prepontine cistern and cavernous sinus. • Assessment is essential for perineural spread of disease and trigeminal neuralgia. • Key imaging: neural enhancement, enlargement, perineural fat/CSF effacement, skull base foraminal changes.

1 October 2020 in RadioGraphics
Verified
Journal Article
Closed access
MRMargarita V. Revzin
Margarita V. Revzin
SRSarah Raza
Sarah Raza
RWRobin Warshawsky
Robin Warshawsky
CDCatherine D’agostino
Catherine D’agostino
NSNeil C. Srivastava
Neil C. Srivastava
JPJohn S. Pellerito
John S. Pellerito
With the growing global COVID-19 outbreak, it is essential for radiologists to understand the viral pathogenesis and the diagnostic imaging hallmarks and varied pathologic manifestations of this in... Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) results in coronavirus disease 2019 (COVID-19), which was declared an official pandemic by the World Health Organization ...

1 November 2020 in RadioGraphics
Verified
Journal Article
Closed access
MRMargarita V. Revzin
Margarita V. Revzin
SRSarah Raza
Sarah Raza
NSNeil C. Srivastava
Neil C. Srivastava
RWRobin Warshawsky
Robin Warshawsky
CDCatherine D’aGostino
Catherine D’aGostino
JPJohn S. Pellerito
John S. Pellerito
In part 2 of this two-part review article, the extrapulmonary imaging manifestations of coronavirus disease 2019 (COVID-19), as well as the pediatric and pregnancy-related manifestations of the vir... Infection with severe acute respiratory syndrome coronavirus 2 results in coronavirus disease 2019 (COVID-19), which was declared an official pandemic by the World Health Organization on March 11, ...

1 December 2022 in Radiology
Verified
Journal Article
Closed access
XWXiao Wu
Xiao Wu
SBSuryansh Bajaj
Suryansh Bajaj
MKMihir Khunte
Mihir Khunte
MRMargarita Revzin
Margarita Revzin
DGDheeraj Gandhi
Dheeraj Gandhi
AMAjay Malhotra
Ajay Malhotra
Identifying reasons for the low proportion of female and underrepresented minority radiology residency applicants, despite a highly diverse pool of medical students, would be key to increasing thei... Background There have been growing efforts nationally and institutionally toward diversity in radiology. Purpose To analyze sex and racial and ethnic diversity over time (2010–2019) for the various...