Giacomo Bonito

Dr. Giacomo Bonito


Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
11 September 2023 in Diagnostics
Verified
Journal Article
Open access
PDF file
Gabriele MasselliGabriele Masselli
Gabriele Masselli
GBGiacomo Bonito
Giacomo Bonito
SGSilvia Gigli
Silvia Gigli
PRPaolo Ricci
Paolo Ricci
Emergency imaging in pregnancy and puerperium poses unique challenges both for clinicians and radiologists, requiring timely and accurate diagnosis. Delay in treatment may result in poor outcomes for both the patient and the foetus. Pregnant and puerperal patients may present in the emergency setting with acute abdominopelvic pain for various complications that can be broadly classified into obstetric and non-obstetric related diseases. Ultrasonography (US) is the primary diagnostic imaging test; however, it may be limited due to the patient’s body habitus and the overlapping of bowel loops. Computed tomography (CT) carries exposure to ionising radiation to the foetus, but may be necessary in selected cases. Magnetic resonance imaging (MRI) is a valuable complement to US in the determination of the etiology of acute abdominal pain and can be used in most settings, allowing for the identification of a broad spectrum of pathologies with a limited protocol of sequences. In this second section, we review the common non-obstetric causes for acute abdominopelvic pain in pregnancy and post partum, offering a practical approach for diagnosis and pointing out the role of imaging methods (US, MRI, CT) with the respective imaging findings.

21 August 2025 in Diagnostics
Verified
Journal Article
Open access
PDF file
EDEmanuele David
Emanuele David
LALorenzo Aliotta
Lorenzo Aliotta
Fabrizio FrezzaFabrizio Frezza
Fabrizio Frezza
MRMarianna Riccio
Marianna Riccio
ACAlessandro Cannavale
Alessandro Cannavale
VCVito Cantisani
Vito Cantisani
Purpose: This study aimed to compare: the performance of K-TIRADS, EU-TIRADS and ACR TIRADS when used by observers with different levels of experience compared with the gold standard of cytology, and to evaluate the diagnostic performance of CAD (computer-aided design) compared with TI-RADS systems. Methods and Materials: In total, 323 thyroid nodules were evaluated in patients who were candidates for needle aspiration. Three observers with different levels of experience evaluated the diagnostic accuracy of three risk stratification systems (ACR TI-RADS, EU-TIRADS and K-TIRADS) and CAD software (S-Detect, made by Samsung) in characterizing the nodules. The results were compared with cytology examination. All nodules were characterized in terms of shape, margins, composition, calcifications, size, echogenicity and microcalcifications, and by stratifying individual nodules by using the three TIRADS systems; then S-detect software was applied and the data were compared with each other and with the gold standard. Results: Through cytology, 308 benign and 33 malignant nodules were identified. ACR-TIRADS showed a sensitivity of 100%, a specificity of 86%, a positive predictive value of 43% and a negative predictive value of 100%. EU-TIRADS showed a sensitivity of 100%, a specificity of 79%, a positive predictive value of 33% and a negative predictive value of 100%. K-TIRADS showed a sensitivity of 100%, a specificity of 89%, a positive predictive value of 50% and a negative predictive value of 100%. S-Detect combined with EU-TIRADS showed a high agreement (>95%) with the gold standard. Conclusions: K-TIRADS’s positive predictive power was slightly better than the other TIRADS, suggesting greater accuracy in correctly diagnosing positive cases. S-DETECT combined with EU-TIRADS has similar results to S-Detect with ACR- and K-TIRADS in terms of sensitivity, specificity and negative predictive power. However, it has a slightly better positive predictive power, suggesting greater accuracy in correctly diagnosing positive cases than the ACR- and K-TIRADS classification systems. In general, S-Detect cannot yet be considered a substitute for the human observer but only as an important support for human evaluation and an excellent and fast help to provide a comprehensive and complete report. Clinical Relevance/Application: S-Detect is a valuable tool for characterizing thyroid nodules when integrated with radiologist evaluation. It is also an important support tool for less experienced observers. Particularly interesting is the approach of use in integrated combination of the K-TIRADS by the human observer with S-Detect using EU-TIRADS, which could increase the overall diagnostic efficiency of the systems.

9 September 2023 in Diagnostics
Verified
Journal Article
Open access
PDF file
GBGiacomo Bonito
Giacomo Bonito
Gabriele MasselliGabriele Masselli
Gabriele Masselli
SGSilvia Gigli
Silvia Gigli
PRPaolo Ricci
Paolo Ricci
Acute abdominopelvic pain in pregnant and postpartum patients presents clinical and therapeutic challenges, often requiring quick and accurate imaging diagnosis. Ultrasound remains the primary imaging investigation. Magnetic resonance imaging (MRI) has been shown to be a powerful diagnostic tool in the setting of acute abdominal pain during pregnancy and puerperium. MRI overcomes some drawbacks of US, avoiding the ionizing radiation exposure of a computed tomography (CT) scan. Although CT is not usually appropriate in pregnant patients, it is crucial in the emergency evaluation of postpartum complications. The aim of this article is to provide radiologists with a thorough familiarity with the common and uncommon pregnancy and puerperium abdominal emergencies by illustrating their imaging appearances. The present first section will review and discuss the imaging findings for acute abdominopelvic pain of obstetric (non-fetal) etiology.

14 June 2024 in Journal of Medical Imaging and Interventional Radiology
Verified
Journal Article
Open access
PDF file
RCRosita Comune
Rosita Comune
Stefania TamburriniStefania Tamburrini
Stefania Tamburrini
ADAdele Durante
Adele Durante
GBGiacomo Bonito
Giacomo Bonito
RFRiccardo Ferrari
Riccardo Ferrari
FPFabio Pinto
Fabio Pinto
Ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) have high diagnostic accuracy in the diagnosis of acute appendicitis. Nowadays imaging is part of the diagnostic algorithm of appendicitis and the advantages are demonstrated by the reduced negative appendectomies rates. US is the preferred first line imaging in acute appendicitis. The US diagnosis of complicated and uncomplicated appendicitis is well characterized by different signs but the paradigm of US to take in mind is that the non-visualization of the appendix cannot exclude acute appendicitis. In US, when the appendix is not visualized, or US is inconclusive, second-line imaging examination should be performed. The aims of this pictorial are 1. to illustrate the US signs of complicated and uncomplicated AA; 2. to describe the conditions in which other imaging modalities should be performed to reach a definitive diagnosis.

5 October 2022 in BJR|Open
Verified
Journal Article
Open access
GBGiacomo Bonito
Giacomo Bonito
VMValeria Martinelli
Valeria Martinelli
FVFrancesco Vullo
Francesco Vullo
FBFabrizio Basilico
Fabrizio Basilico
EPEleonora Polito
Eleonora Polito
PRPaolo Ricci
Paolo Ricci
Typical radiologic images of Covid-19 pneumonia consists in a wide spectrum of chest manifestations, which range from peripheral predominant ground-glass opacities to an organizing pneumonia pattern, with additional features including crazy-paving, consolidations, fibrotic streaks and linear opacities. With variants imaging profile of Covid-19 evolves, producing relatively atypical/indeterminate CT pattern of pulmonary involvement, which overlap with imaging features of a variety of other respiratory diseases, including infections, drug reaction and hypersensitivity pneumonia. Our knowledge of these radiological findings is incomplete and there is a need to strengthen the recognition of the many faces of Covid-19 pneumonia.

3 June 2025
Verified
Book Chapter
Closed access
PDF file
GBGiacomo Bonito
Giacomo Bonito
SGSilvia Gigli
Silvia Gigli
LCLaura Corso
Laura Corso
LMLucia Malzone
Lucia Malzone
MMMonica Mattone
Monica Mattone
PRPaolo Ricci
Paolo Ricci