Saba Zanganeh

Saba Zanganeh


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2022 in Critical Reviews in Oncology/Hematology
Verified
Journal Article
Closed access
NHNiloofar Asadi Hanjani
Niloofar Asadi Hanjani
NENazanin Esmaelizad
Nazanin Esmaelizad
SZSaba Zanganeh
Saba Zanganeh
AGAbdulwahab Teflischi Gharavi
Abdulwahab Teflischi Gharavi
PHPegah Heidarizadeh
Pegah Heidarizadeh
Mohammad DoroudianMohammad Doroudian
Mohammad Doroudian

1 September 2021 in Journal of Environmental Management
Verified
Journal Article
Closed access
MZMohammad Zahed
Mohammad Zahed
EMElaheh Movahed
Elaheh Movahed
AKArezoo Khodayari
Arezoo Khodayari
SZSaba Zanganeh
Saba Zanganeh
MBMaryam Badamaki
Maryam Badamaki

17 March 2023 in Frontiers in Bioengineering and Biotechnology
Verified
Journal Article
Open access
MDMohammad Doroudian
Mohammad Doroudian
SZSaba Zanganeh
Saba Zanganeh
EAElham Abbasgholinejad
Elham Abbasgholinejad
SDSeamas C. Donnelly
Seamas C. Donnelly
Lung cancer is the major cause of cancer death worldwide. Cancer immunotherapy has been introduced as a promising and effective treatment that can improve the immune system’s ability to eliminate cancer cells and help establish immunological memory. Nanoparticles can contribute to the rapidly evolving field of immunotherapy by simultaneously delivering a variety of immunological agents to the target site and tumor microenvironment. Nano drug delivery systems can precisely target biological pathways and be implemented to reprogram or regulate immune responses. Numerous investigations have been conducted to employ different types of nanoparticles for immunotherapy of lung cancer. Nano-based immunotherapy adds a strong tool to the diverse collection of cancer therapies. This review briefly summarizes the remarkable potential opportunities for nanoparticles in lung cancer immunotherapy and its challenges.

26 July 2023 in Cancers
Verified
Journal Article
Open access
PDF file
SZSaba Zanganeh
Saba Zanganeh
EAElham Abbasgholinejad
Elham Abbasgholinejad
Mohammad DoroudianMohammad Doroudian
Mohammad Doroudian
NENazanin Esmaelizad
Nazanin Esmaelizad
FFFatemeh Farjadian
Fatemeh Farjadian
Rahima S BenhabbourRahima S Benhabbour
Rahima S Benhabbour
Glioblastoma (GBM) is a highly aggressive and lethal primary brain cancer that necessitates early detection and accurate diagnosis for effective treatment and improved patient outcomes. Traditional diagnostic methods, such as imaging techniques and tissue biopsies, have limitations in providing real-time information and distinguishing treatment-related changes from tumor progression. Liquid biopsies, used to analyze biomarkers in body fluids, offer a non-invasive and dynamic approach to detecting and monitoring GBM. This article provides an overview of GBM biomarkers in body fluids, including circulating tumor cells (CTCs), cell-free DNA (cfDNA), cell-free RNA (cfRNA), microRNA (miRNA), and extracellular vesicles. It explores the clinical utility of these biomarkers for GBM detection, monitoring, and prognosis. Challenges and limitations in implementing liquid biopsy strategies in clinical practice are also discussed. The article highlights the potential of liquid biopsies as valuable tools for personalized GBM management but underscores the need for standardized protocols and further research to optimize their clinical utility.

12 July 2023 in Advanced Therapeutics
Verified
Journal Article
Closed access
SZSaba Zanganeh
Saba Zanganeh
Mohammad DoroudianMohammad Doroudian
Mohammad Doroudian
ZNZohreh R. Nowzari
Zohreh R. Nowzari
PNPourya Nasirmoghadas
Pourya Nasirmoghadas
JNJavid Sadri Nahand
Javid Sadri Nahand
MMMohsen Moghoofei
Mohsen Moghoofei

27 December 2021 in Reviews in Medical Virology
Verified
Journal Article
Open access
PDF file
SZSaba Zanganeh
Saba Zanganeh
NGNima Goodarzi
Nima Goodarzi
Mohammad DoroudianMohammad Doroudian
Mohammad Doroudian
EMElaheh Movahed
Elaheh Movahed
Summary: COVID‐19 has spread swiftly throughout the world posing a global health emergency. The significant numbers of deaths attributed to this pandemic have researchers battling to understand this new, dangerous virus. Researchers are looking to find possible treatment regimens and develop effective therapies. This study aims to provide an overview of published scientific information on potential treatments, emphasizing angiotensin‐converting enzyme II (ACE2) inhibitors as one of the most important drug targets. SARS‐CoV‐2 receptor‐binding domain (RBD); as a viral attachment or entry inhibitor against SARS‐CoV‐2, human recombinant soluble ACE2; as a genetically modified soluble form of ACE2 to compete with membrane‐bound ACE2, and microRNAs (miRNAs); as a negative regulator of the expression of ACE2/TMPRSS2 to inhibit SARS‐CoV2 entry into cells, are the potential therapeutic approaches discussed thoroughly in this article. This review provides the groundwork for the ongoing development of therapeutic agents and effective treatments against SARS‐COV‐2.