Article A statistical overview of standard (IUPAC and ACS) and new procedures for determining the limits of detection and quantification: Application to voltammetric and stripping techniques (Technical Report) was published on February 28, 1997 in the journal Pure and Applied Chemistry (volume 69, issue 2).

Evf2 is a polyadenylated, noncoding RNA that is transcribed from the intergenic region of Dlx5 and Dlx6, which are genes for homeodomain transcriptional factors. The authors now show that the loss of Evf2 in mice results in a substantial reduction of GABAergic interneurons via interference with Dlx5/6 expression. Genomic studies demonstrate that, although the majority of the mammalian genome is transcribed, only about 2% of these transcripts are code for proteins. We investigated how the long, polyadenylated Evf2 noncoding RNA regulates transcription of the homeodomain transcription factors DLX5 and DLX6 in the developing mouse forebrain. We found that, in developing ventral forebrain, Evf2 recruited DLX and MECP2 transcription factors to important DNA regulatory elements in the Dlx5/6 intergenic region and controlled Dlx5, Dlx6 and Gad1 expression through trans and cis-acting mechanisms. Evf2 mouse mutants had reduced numbers of GABAergic interneurons in early postnatal hippocampus and dentate gyrus. Although the numbers of GABAergic interneurons and Gad1 RNA levels returned to normal in Evf2 mutant adult hippocampus, reduced synaptic inhibition occurred. These results suggest that noncoding RNA–dependent balanced gene regulation in embryonic brain is critical for proper formation of GABA-dependent neuronal circuitry in adult brain.

Twisted bismuth nanowire (BiNW) with abundant crystal lattice dislocations is a highly active electrocatalyst for CO ₂ reduction to formate at low overpotential.