Due to the limited memory and computing resources in the real application of target detection, the method is challenging to implement on mobile and embedded devices. In order to achieve the balance between detection accuracy and speed in pedestrian-intensive scenes, an improved lightweight dense pedestrian detection algorithm GS-YOLOv5 (GhostNet GSConv- SIoU) is proposed in this paper. In the Backbone section, GhostNet is used to replace the original CSPDarknet53 network structure, reducing the number of parameters and computation. The CBL module is replaced with GSConv in the Head section, and the CSP module is replaced with VoV-GSCSP. The SloU loss function is used to replace the original IoU loss function to improve the prediction box overlap problem in dense scenes. The model parameters are reduced by 40% and the calculation amount is reduced by 64% without losing the average accuracy, and the detection accuracy is improved by 0.5%. The experimental results show that the GS-YOLOv5 can detect pedestrians more effectively under limited hardware conditions to cope with dense pedestrian scenes, and it is suitable for the online real-time detection of pedestrians.

The combination of a blood cell analyzer and artificial microscopy to detect white blood cells is used in hospitals. Blood cell analyzers not only have large throughput, but they also cannot detect cell morphology; although artificial microscopy has high accuracy, it is inefficient and prone to missed detections. In view of the above problems, a method based on Fourier ptychographic microscopy (FPM) and deep learning to detect peripheral blood leukocytes is proposed in this paper. Firstly, high-resolution and wide-field microscopic images of human peripheral blood cells are obtained using the FPM system, and the cell image data are enhanced with DCGANs (deep convolution generative adversarial networks) to construct datasets for performance evaluation. Then, an improved DETR (detection transformer) algorithm is proposed to improve the detection accuracy of small white blood cell targets; that is, the residual module Conv Block in the feature extraction part of the DETR network is improved to reduce the problem of information loss caused by downsampling. Finally, CIOU (complete intersection over union) is introduced as the bounding box loss function, which avoids the problem that GIOU (generalized intersection over union) is difficult to optimize when the two boxes are far away and the convergence speed is faster. The experimental results show that the mAP of the improved DETR algorithm in the detection of human peripheral white blood cells is 0.936. In addition, this algorithm is compared with other convolutional neural networks in terms of average accuracy, parameters, and number of inference frames per second, which verifies the feasibility of this method in microscopic medical image detection.