In this review, the conservation methods for various types of cultural relics enabled by hyperspectral imaging are summarized, and the hyperspectral cameras and techniques utilized in the process from data acquisition to analyzation are introduced. Hyperspectral imaging is characterized by non-contact detection, broadband, and high resolution, which are of great significance to the non-destructive investigation of cultural relics. However, owing to the wide variety of cultural relics, the utilized equipment and methods vary greatly in the investigations of the associated conservation. Previous studies generally select a single type of cultural relic for conservation. That is, seldom study has focused on the application of hyperspectral techniques to generalized conservation methods that are simultaneously suitable for different types of cultural relics. Hence, some widely used hyperspectral cameras and imaging systems are introduced first. Subsequently, according to the previous investigations, the methods used for image acquisition, image correction, and data dimensionality reduction in hyperspectral techniques are described. Thirdly, a summary of methods in cultural relic conservation based on hyperspectral techniques is presented, which involves pigments, grottoes and murals, and painting and calligraphy. Later, some challenges and potential development prospects in hyperspectral-based methods are discussed for future study. Finally, the conclusions are given.