Yiling Zhang

Yiling Zhang


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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22 March 2022 in Frontiers in Medicine
Verified
Journal Article
Open access
XCXi Chen
Xi Chen
XLXingyu Liu
Xingyu Liu
YWYiou Wang
Yiou Wang
RMRuichen Ma
Ruichen Ma
SZShibai Zhu
Shibai Zhu
Wenwei QianWenwei Qian
Wenwei Qian
Background: Accurate preoperative planning is essential for successful total hip arthroplasty (THA). However, the requirements of time, manpower, and complex workflow for accurate planning have limited its application. This study aims to develop a comprehensive artificial intelligent preoperative planning system for THA (AIHIP) and validate its accuracy in clinical performance.Methods: Over 1.2 million CT images from 3,000 patients were included to develop an artificial intelligence preoperative planning system (AIHIP). Deep learning algorithms were developed to facilitate automatic image segmentation, image correction, recognition of preoperative deformities and postoperative simulations. A prospective study including 120 patients was conducted to validate the accuracy, clinical outcome and radiographic outcome.Results: The comprehensive workflow was integrated into the AIHIP software. Deep learning algorithms achieved an optimal Dice similarity coefficient (DSC) of 0.973 and loss of 0.012 at an average time of 1.86 ± 0.12 min for each case, compared with 185.40 ± 21.76 min for the manual workflow. In clinical validation, AIHIP was significantly more accurate than X-ray-based planning in predicting the component size with more high offset stems used.Conclusion: The use of AIHIP significantly reduced the time and manpower required to conduct detailed preoperative plans while being more accurate than traditional planning method. It has potential in assisting surgeons, especially beginners facing the fast-growing need for total hip arthroplasty with easy accessibility.

1 September 2021 in Computer Methods and Programs in Biomedicine
Verified
Journal Article
Closed access
PWPeixu Wang
Peixu Wang
XLXingyu Liu
Xingyu Liu
JXJia Xu
Jia Xu
TLTengqi Li
Tengqi Li
WSWei Sun
Wei Sun
YAYicheng An
Yicheng An

13 December 2023 in Bioengineering
Verified
Journal Article
Open access
PDF file
SLSonglin Li
Songlin Li
XLXingyu Liu
Xingyu Liu
XCXi Chen
Xi Chen
HXHongjun Xu
Hongjun Xu
YZYiling Zhang
Yiling Zhang
Wenwei QianWenwei Qian
Wenwei Qian
Background: Accurate preoperative planning for total knee arthroplasty (TKA) is crucial. Computed tomography (CT)-based preoperative planning offers more comprehensive information and can also be used to design patient-specific instrumentation (PSI), but it requires well-reconstructed and segmented images, and the process is complex and time-consuming. This study aimed to develop an artificial intelligence (AI) preoperative planning and PSI system for TKA and to validate its time savings and accuracy in clinical applications. Methods: The 3D-UNet and modified HRNet neural network structures were used to develop the AI preoperative planning and PSI system (AIJOINT). Forty-two patients who were scheduled for TKA underwent both AI and manual CT processing and planning for component sizing, 20 of whom had their PSIs designed and applied intraoperatively. The time consumed and the size and orientation of the postoperative component were recorded. Results: The Dice similarity coefficient (DSC) and loss function indicated excellent performance of the neural network structure in CT image segmentation. AIJOINT was faster than conventional methods for CT segmentation (3.74 ± 0.82 vs. 128.88 ± 17.31 min, p < 0.05) and PSI design (35.10 ± 3.98 vs. 159.52 ± 17.14 min, p < 0.05) without increasing the time for size planning. The accuracy of AIJOINT in planning the size of both femoral and tibial components was 92.9%, while the accuracy of the conventional method in planning the size of the femoral and tibial components was 42.9% and 47.6%, respectively (p < 0.05). In addition, AI-based PSI improved the accuracy of the hip–knee–ankle angle and reduced postoperative blood loss (p < 0.05). Conclusion: AIJOINT significantly reduces the time needed for CT processing and PSI design without increasing the time for size planning, accurately predicts the component size, and improves the accuracy of lower limb alignment in TKA patients, providing a meaningful supplement to the application of AI in orthopaedics.

15 November 2023 in International Orthopaedics
Verified
Journal Article
Open access
PDF file
WYWeihua Yang
Weihua Yang
TGTianyi Gao
Tianyi Gao
XLXingyu Liu
Xingyu Liu
KSKaiwei Shen
Kaiwei Shen
FLFeitai Lin
Feitai Lin
YZYiling Zhang
Yiling Zhang
Purpose: The objective of this study was to investigate the efficacy of an artificial intelligence-assisted 3D planning system (AIHIP) in total hip arthroplasty by direct anterior approach and assess the reliability of the AIHIP preoperative program in terms of both interobserver and intraobserver agreement. Methods: A retrospective analysis was conducted on patients who underwent unilateral primary THA via direct anterior approach from June 2019 to March 2022. Participants were randomly assigned to receive either the AIHIP system (n = 220) or the 2D template (control group) (n = 220) for preoperative planning. The primary outcome aimed to evaluate the correspondence between the prosthesis selected intro-operation and the one planned preoperatively, as well as to calculate the intraclass correlation coefficient (ICC). Secondary outcomes included operation time, intraoperative blood loss, fluoroscopy times, Harris hip score (HHS), lower limb length difference (LLD), femoral offset (FO), and bilateral femoral offset difference. Results: No significant differences were observed in gender, age, body mass index (BMI), aetiology, and American Society of Anesthesiologists (ASA) score between the two groups. Both planning methods exhibited good intraobserver agreement for component planning (ICC: 0.941–0.976). Interobserver agreement for component planning was comparable between the two methods (ICC: 0.882–0.929). In the AIHIP group, the accuracy of acetabular cup and femoral stem prosthetics planning significantly improved, with accuracies within the size range of ± 0 and ± 1 being 76.8% and 90.5% and 79.5% and 95.5%, respectively. All differences between two groups were statistically significant (p < 0.05). Patients receiving AIHIP preoperative planning experienced shorter operation times, reduced intraoperative blood loss, fewer fluoroscopy times, and lower leg length discrepancy (LLD) (p < 0.05). Moreover, they demonstrated a higher Harris hip score (HHS) at three days post-surgery (p < 0.05). However, no significant differences were found in femoral offset (FO), difference of bilateral femoral offsets, and HHS at 1 month after the operation. Conclusion: Utilizing AIHIP for preoperative planning of direct anterior approach THA can significantly enhance the accuracy of prosthetic sizing with good reliability, decrease operation time, reduce intraoperative blood loss, and more effectively restore the length of both lower limbs. This approach has greater clinical application value.

15 March 2022 in Journal of Orthopaedic Surgery and Research
Verified
Journal Article
Open access
PDF file
DWDong Wu
Dong Wu
XZXin Zhi
Xin Zhi
XLXingyu Liu
Xingyu Liu
YZYiling Zhang
Yiling Zhang
WCWei Chai
Wei Chai
Purpose: Preoperative three-dimensional planning is important for total hip arthroplasty. To simulate the placement of joint implants on computed tomography (CT), pelvis and femur must be segmented. Accurate and rapid segmentation of the hip joint is challenging. This study aimed to develop a novel deep learning network, named Changmugu Net (CMG Net), which could achieve accurate segmentation of the femur and pelvis. Methods: The overall deep neural network architecture of CMG Net employed three interrelated modules. CMG Net included the 2D U-net to separate the bony and soft tissues. The modular hierarchy method was used for the main femur segmentation to achieve better performance. A layer classifier was adopted to localise femur layers among a series of CT scan images. The first module was a modified 2D U-net, which separated bony and soft tissues; it provided intermediate supervision for the main femur segmentation. The second module was the main femur segmentation, which was used to distinguish the femur from the acetabulum. The third module was the layer classifier, which served as a post-processor for the second module. Results: There was a much greater overlap in accuracy results with the “gold standard” segmentation than with competing networks. The dice overlap coefficient was 93.55% ± 5.57%; the mean surface distance was 1.34 ± 0.24 mm, and the Hausdorff distance was 4.19 ± 1.04 mm in the normal and diseased hips, which indicated greater accuracy than the other four competing networks. Moreover, the mean segmentation time of CMG Net was 25.87 ± 2.73 s, which was shorter than the times of the other four networks. Conclusions: The prominent segmentation accuracy and run-time of CMG Net suggest that it is a reliable method for clinicians to observe anatomical structures of the hip joints, even in severely diseased cases.

22 January 2025 in Frontiers in Bioengineering and Biotechnology
Verified
Journal Article
Open access
PDF file
AWAobo Wang
Aobo Wang
TWTianyi Wang
Tianyi Wang
XLXingyu Liu
Xingyu Liu
NFNing Fan
Ning Fan
SYShuo Yuan
Shuo Yuan
LZLei Zang
Lei Zang
Background: The high prevalence of low back pain has led to an increasing demand for the analysis of lumbar magnetic resonance (MR) images. This study aimed to develop and evaluate a deep-learning-assisted automated system for diagnosing and grading lumbar intervertebral disc degeneration based on lumbar T2-weighted sagittal and axial MR images.Methods: This study included a total of 472 patients who underwent lumbar MR scans between January 2021 and November 2023, with 420 in the internal dataset and 52 in the external dataset. The MR images were evaluated and labeled by experts according to current guidelines, and the results were considered the ground truth. The annotations included the Pfirrmann grading of disc degeneration, disc herniation, and high-intensity zones (HIZ). The automated diagnostic model was based on the YOLOv5 network, modified by adding an attention module in the Cross Stage Partial part and a residual module in the Spatial Pyramid Pooling-Fast part. The model’s diagnostic performance was evaluated by calculating the precision, recall, F1 score, and area under the receiver operating characteristic curve.Results: In the internal test set, the model achieved precisions of 0.78–0.91, 0.90–0.92, and 0.82 and recalls of 0.86–0.91, 0.90–0.93, and 0.81–0.88 for disc degeneration grading, disc herniation diagnosis, and HIZ detection, respectively. In the external test set, the precision values for disc degeneration grading, herniation diagnosis, and HIZ detection were 0.73–0.87, 0.86–0.92, and 0.74–0.84 and recalls were 0.79–0.87, 0.88–0.91, and 0.77–0.78, respectively.Conclusion: The proposed model demonstrated a relatively high diagnostic and classification performance and exhibited considerable consistency with expert evaluation.