Background: Optimal glycemic management is critical since it can predict all associated essential causes of death, even after accounting for other risk factors. Objectives: This study investigated the factors associated with glycemic control in patients with type 2 diabetes mellitus (T2DM), particularly self-care behaviors. Methods: An analytical cross-sectional study examined 385 patients with T2DM in 1 general and 17 community hospitals in Kalasin Province. The samples were collected using mixed-method sampling. Data were collected using a validated questionnaire with six parts and laboratory examination records between September 2021 and December 2022. Descriptive statistics (e.g., percentages and means ± SD) were used to analyze the data. The relationship between relevant factors and lack of glycemic control was analyzed by multivariate logistic regression using SPSS version 25. Results: Results showed that most patients were female (78.18%), and the mean age was 59.84 ± 9.05 years. Additionally, a significant proportion of the patients (79.74%) had poor glycemic control. Several factors are significantly associated with poor glycemic control in patients with T2DM. These factors included subjects under the age of 60 years (OR = 2.95, 95% CI: 1.57 to 5.54; p-value < 0.001), a diabetes duration of over 10 years (OR = 3.95, 95% CI: 1.90 to 8.22; p-value < 0.001), poor knowledge about diabetes (OR = 3.92, 95% CI: 1.59 to 9.67; p-value < 0.003), and inadequate self-care behaviors (OR = 6.12, 95% CI: 3.20 to 11.68; p-value < 0.001). Conclusions: In conclusion, proper interventions for controlling glycemic level behaviors are necessary to improve proper self-care behaviors in patients who have a low knowledge level of T2DM, have had diabetes for over ten years, and are aged < 60 years. This approach can reduce the likelihood of experiencing disabilities and economic hardship.
Background: Individuals receiving intensive care are particularly vulnerable to developing pressure sores. This heightened risk necessitates a thorough understanding of relevant risk factors and the time at which these injuries manifest, facilitating effective prevention. Objective: This investigation, structured as a retrospective cohort study, aimed to assess the duration until pressure sore onset and identify contributing risk factors among 50 adult patients in an intensive care unit (ICU), observed over 12 weeks. Methodology: Our analysis employed the Kaplan–Meier approach for survival analysis. We then used the log-rank test to determine significant differences in survival curves. We utilized COX proportional regression analysis to explore the associations between various factors and the development of pressure injuries during the ICU stay. Results: Data from 50 adult ICU patients showed that 29 patients developed pressure sores. Coccyx (44%) and back (6%) were most affected. The median survival time from ICU admission to the final skin examination for pressure sore development was 3 days. The multivariable Cox regression analysis revealed that males with a high BMI, increased systolic blood pressure, elevated albumin levels, and a more extended ICU stay were at a significantly higher risk of developing pressure ulcers (p-value < 0.05). Conclusions: The research highlights the need to prioritize males with high BMI, high blood pressure, and high albumin patients in preventing pressure sores in the ICU, with an extended ICU stay significantly increasing the risk. This information can be utilized to develop clinical guidelines for reducing pressure sore incidence and improving patient care.
Background: Type 2 diabetes mellitus (T2DM) is a major public health problem in Thailand, particularly in rural areas where individuals have limited access to structured diabetes care and education. Poor self-management contributes to uncontrolled glycemic levels and long-term complications. Objectives: This study evaluated the effectiveness of a community-based health care program on glycemic control and self-care behaviors among adults with uncontrolled T2DM. Methods: A quasi-experimental study was conducted among 80 patients with uncontrolled T2DM in Kalasin Province. Participants were assigned to either an intervention group (n = 40) or a comparison group (n = 40). The 12-week intervention consisted of diabetes self-management education, individualized lifestyle support, and community/family engagement. Diabetes self-care behavior and glycated hemoglobin (HbA1c) were assessed at baseline and Week 12. Statistical analyses included paired t-test, independent t-test, and 95% confidence intervals. Results: The intervention group demonstrated a significant improvement in self-care behavior (MD = 14.83; p < 0.0001), compared with a minimal change in the comparison group (0.80; p = 0.756). HbA1c levels significantly decreased in the intervention group (−0.47%; 95% CI: −0.61 to −0.33; p < 0.0001), while a slight nonsignificant increase was observed in the comparison group (0.11%; p = 0.210). The between-group analysis showed a significant reduction in HbA1c favoring the intervention (−0.92%; p < 0.0001), supported by a large effect size (Hedges’ g = 0.87). Conclusions: This community-based health care program effectively enhanced diabetes self-management behaviors and improved glycemic control. Integrating such behavioral support into primary health care services may strengthen long-term diabetes management and reduce complications among patients with uncontrolled T2DM.
1 September 2020 in Journal of Clinical and Diagnostic Research
Introduction: Drug-Induced Hepatotoxicity (DIH) is usually found in patients with Tuberculosis (TB) who have received the standard anti-TB treatment due to the specific drugs in the standard regimen as well as other factors. Hepatotoxicity is the main cause of drug discontinuation and influences drug resistance and fulminant hepatitis in patients with TB. Aim: This study aims to assess the factors enhancing DIH in patients with TB who received the standard anti-TB regiment in Phichit Hospital, Thailand. Materials and Methods: A retrospective study was used to examine factors that enhanced DIH in 327 new patients with TB who received the standard anti-TB treatment at the TB-clinic in Phichit Hospital from October 1st, 2016 to September 30th, 2018. Data was collected from medical and laboratory records at the TB clinic. The univariate and multivariate logistic regression were used to assess factors enhancing DIH in patients with TB, reported using an Adjusted Odd Ratio (AOR) of 95% CI and a p-value of 60 years was associated with an increased risk of DIH development {AOR 2.87 (95% CI 1.16 to 7.14), p=0.02}. Conclusion: For TB patients, being over 60-year-old and malnutrition are significant factors related to DIH. Therefore, the new patients with TB should receive the screening for present chronic liver disease, including AST and ALT whenever feasible, and nutritional assessment should be done for elderly patients before start of anti-TB treatment.
9 September 2024 in Journal of Public Health and Development
A cross-sectional study was conducted to investigate factors related to self-care behavior for diabetes mellitus prevention among 393 Thai Buddhist monks in the upper northeastern region of Thailand. Data were collected using questionnaires and analyzed using descriptive statistics, including percentages, means, minimums, maximums, and standard deviations. Relationships between factors related to self-care behaviors among Buddhist monks were analyzed using bivariate analysis (chi-square test) and multivariate analysis (binary logistic regression). The findings demonstrated that significant factors included age under 35 years (AOR=5.34, 95% CI=2.02-14.14), eating two meals per day (AOR=2.99, 95% CI=1.33-6.76), self-management (AOR=6.51, 95% CI=3.52-12.02), access to health information and health services (AOR=0.26, 95% CI=0.15-0.47), and making correct health decisions (AOR=1.98, 95% CI=1.04-3.78). These factors were significantly related to self-care behaviors among Buddhist monks (p < 0.05). The study concludes that improving health literacy among Thai Buddhist monks, particularly those under 35 years of age, is crucial for effective T2DM prevention. Targeted health education programs can significantly enhance their self-management skills, enable them to make informed health decisions, and encourage the adoption of better self-care and consumption behaviors.
Diabetes Mellitus (DM) is a major public health problem worldwide. Most of the problems are caused by uncontrolled blood sugar level, resulting in complications and possible death. This study aimed to investigate the prevalence and distribution of uncontrolled type 2 diabetes mellitus (T2DM). A cross-sectional of 385 patients between September 2019 and December 2019, using the google maps, a questionnaire and laboratory examination. The results revealed that the prevalence of uncontrolled T2DM was 79.74% and densely distributed in the municipality. This data indicates that the prevalence and distribution of uncontrolled T2DM need to be concern and solve problems to decrease complications and death rates from diabetes.