We have developed a technique to study how good computers can be at diagnosing gastrointestinal lesions from regular (white light and narrow banded) colonoscopic videos compared to two levels of clinical knowledge (expert and beginner). Our technique includes a novel tissue classification approach which may save clinician's time by avoiding chromoendoscopy, a time-consuming staining procedure using indigo carmine. Our technique also discriminates the severity of individual lesions in patients with many polyps, so that the gastroenterologist can directly focus on those requiring polypectomy. Technically, we have designed and developed a framework combining machine learning and computer vision algorithms, which performs a virtual biopsy of hyperplastic lesions, serrated adenomas and adenomas. Serrated adenomas are very difficult to classify due to their mixed/hybrid nature and recent studies indicate that they can lead to colorectal cancer through the alternate serrated pathway. Our approach is the first step to avoid systematic biopsy for suspected hyperplastic tissues. We also propose a database of colonoscopic videos showing gastrointestinal lesions with ground truth collected from both expert image inspection and histology. We not only compare our system with the expert predictions, but we also study if the use of 3D shape features improves classification accuracy, and compare our technique's performance with three competitor methods.

This paper proposes a grid impedance monitoring system for distributed power generation electronic interfaces. The system estimates the grid equivalent impedance and voltage source from the voltage measurements performed at the point of common coupling. The estimation algorithm is based on a recursive least-squares algorithm implemented in the complex field. Simultaneously, the system evaluates the quality of the estimation, minimizing its influence on the grid and detecting islanding situations. The proposed system performance has been evaluated under experimental testing.

This paper presents a novel approach for indoor acoustic source localization using microphone arrays, based on a Convolutional Neural Network (CNN). In the proposed solution, the CNN is designed to directly estimate the three-dimensional position of a single acoustic source using the raw audio signal as the input information and avoiding the use of hand-crafted audio features. Given the limited amount of available localization data, we propose, in this paper, a training strategy based on two steps. We first train our network using semi-synthetic data generated from close talk speech recordings. We simulate the time delays and distortion suffered in the signal that propagate from the source to the array of microphones. We then fine tune this network using a small amount of real data. Our experimental results, evaluated on a publicly available dataset recorded in a real room, show that this approach is able to produce networks that significantly improve existing localization methods based on SRP-PHAT strategies and also those presented in very recent proposals based on Convolutional Recurrent Neural Networks (CRNN). In addition, our experiments show that the performance of our CNN method does not show a relevant dependency on the speaker’s gender, nor on the size of the signal window being used.

We study a problem that we call Shape-from-Template, which is the problem of reconstructing the shape of a deformable surface from a single image and a 3D template. Current methods in the literature address the case of isometric deformations, and relax the isometry constraint to the convex inextensibility constraint, solved using the so-called maximum depth heuristic. We call these methods zeroth-order since they use image point locations (the zeroth-order differential structure) to solve the shape inference problem from a perspective image. We propose a novel class of methods that we call first-order. The key idea is to use both image point locations and their first-order differential structure. The latter can be easily extracted from a warp between the template and the input image. We give a unified problem formulation as a system of PDEs for isometric and conformal surfaces that we solve analytically. This has important consequences. First, it gives the first analytical algorithms to solve this type of reconstruction problems. Second, it gives the first algorithms to solve for the exact constraints. Third, it allows us to study the well-posedness of this type of reconstruction: we establish that isometric surfaces can be reconstructed unambiguously and that conformal surfaces can be reconstructed up to a few discrete ambiguities and a global scale. In the latter case, the candidate solution surfaces are obtained analytically. Experimental results on simulated and real data show that our isometric methods generally perform as well as or outperform state of the art approaches in terms of reconstruction accuracy, while our conformal methods largely outperform all isometric methods for extensible deformations.

This paper presents a current control scheme for a voltage-source converter connected to the grid through an LCL filter. The proposed current control is based on the linear quadratic (LQ) Gaussian (LQG) servo controller technique, which combines the LQ regulator and the Kalman filter (KF). The use of the KF instead of a Luenberger estimator improves the quality of the estimation of state variables in noisy environments, increasing the noise immunity of the control loop. This paper focuses on giving some criteria and practical hints to choose both the KF and LQ design parameters to achieve null steady-state tracking error, channel decoupling, and noise immunity. Furthermore, this paper analyzes the steady-state KF approximation that allows a significant decrement in the computational complexity of the algorithm at nearly no cost in accuracy. Simulation and experimental results prove the correct operation of the proposed LQG current control and the possible advantages of using KF to estimate the state vector.

A major research area in Computer Assisted Intervention (CAI) is to aid laparoscopic surgery teams with Augmented Reality (AR) guidance. This involves registering data from other modalities such as MR and fusing it with the laparoscopic video in real-time, to reveal the location of hidden critical structures. We present the first system for AR guided laparoscopic surgery of the uterus. This works with pre-operative MR or CT data and monocular laparoscopes, without requiring any additional interventional hardware such as optical trackers. We present novel and robust solutions to two main sub-problems: the initial registration, which is solved using a short exploratory video, and update registration, which is solved with real-time tracking-by-detection. These problems are challenging for the uterus because it is a weakly-textured, highly mobile organ that moves independently of surrounding structures. In the broader context, our system is the first that has successfully performed markerless real-time registration and AR of a mobile human organ with monocular laparoscopes in the OR.