AlgPred 2.0 is a web server developed for predicting allergenic proteins and allergenic regions in a protein. It is an updated version of AlgPred developed in 2006. The dataset used for training, testing and validation consists of 10 075 allergens and 10 075 non-allergens. In addition, 10 451 experimentally validated immunoglobulin E (IgE) epitopes were used to identify antigenic regions in a protein. All models were trained on 80% of data called training dataset, and the performance of models was evaluated using 5-fold cross-validation technique. The performance of the final model trained on the training dataset was evaluated on 20% of data called validation dataset; no two proteins in any two sets have more than 40% similarity. First, a Basic Local Alignment Search Tool (BLAST) search has been performed against the dataset, and allergens were predicted based on the level of similarity with known allergens. Second, IgE epitopes obtained from the IEDB database were searched in the dataset to predict allergens based on their presence in a protein. Third, motif-based approaches like multiple EM for motif elicitation/motif alignment and search tool have been used to predict allergens. Fourth, allergen prediction models have been developed using a wide range of machine learning techniques. Finally, the ensemble approach has been used for predicting allergenic protein by combining prediction scores of different approaches. Our best model achieved maximum performance in terms of area under receiver operating characteristic curve 0.98 with Matthew’s correlation coefficient 0.85 on the validation dataset. A web server AlgPred 2.0 has been developed that allows the prediction of allergens, mapping of IgE epitope, motif search and BLAST search (https://webs.iiitd.edu.in/raghava/algpred2/).
Students may encounter problems concentrating during a lecture due to various reasons, which can be related to the educator’s accent or the student’s auditory difficulties. This may lead to reduced participation and poor performance in the class. In this paper, we explored whether the incorporation of the humanoid robot Pepper can help in improving the learning experience. Pepper can capture the audio of a person; however, there is no guarantee of accuracy of the recorded audio due to various factors. Therefore, we investigated the limitations of Pepper’s speech recognition system with the aim of observing the effect of distance, age, gender, and the complexity of statements. We conducted an experiment with eight persons including five females and three males who spoke provided statements at different distances. These statements were classified using different statistical scores. Pepper does not have the functionality to transcribe speeches into text. To overcome this problem, we integrated Pepper with a speech-to-text recognition tool, Whisper, which transcribes speech into text that can be displayed on Pepper’s screen using its service. The purpose of the study is to develop a system where the humanoid robot Pepper and the speech-to-text recognition tool Whisper act in synergy to bridge the gap between verbal and visual communication in education. This system could be beneficial for students as they will better understand the content through the visual representation of the teacher’s spoken words regardless of any hearing impairments and accent problems. The methodology involves recording the participant’s speech, followed by its transcription to text by Whisper, and then evaluation of the generated text using various statistical scores. We anticipate that the proposed system will be able to increase the student’s learning experience, engagement, and immersion in a classroom environment.
The application of social robots is increasing daily due to their various capabilities. In real settings, social robots have been successfully deployed in multiple domains, such as health, education, and the service industry. However, it is crucial to identify the strengths and limitations of a social robot before it can be employed in a real-life scenario. In this study, we explore and examine the capabilities of a humanoid robot, ‘Pepper’, which can be programmed to interact with humans. The present paper investigates five capabilities of Pepper: mapping and navigation, speech, hearing, object detection, and face detection. We attempt to study each of these capabilities in-depth with the help of experiments conducted in the laboratory. It has been identified that Pepper’s sound and speech recognition capabilities yielded satisfactory results, even with various accents. On the other hand, Pepper’s built-in SLAM navigation is unreliable, making it difficult to reach destinations accurately due to generated maps. Moreover, its object and face detection capabilities delivered inconsistent outcomes. This shows that Pepper has potential for improvement in its current capabilities. However, previous studies showed that with the integration of artificial intelligence techniques, a social robot’s capabilities can be enhanced significantly. In the future, we will focus on such integration in the Pepper robot, and the present study’s exploration will help to establish a baseline comprehension of the in-built artificial intelligence of Pepper. The findings of the present paper provide insights to researchers and practitioners planning to use the Pepper robot in their future work.
Speech comprehension can be challenging due to multiple factors, causing inconvenience for both the speaker and the listener. In such situations, using a humanoid robot, Pepper, can be beneficial as it can display the corresponding text on its screen. However, prior to that, it is essential to carefully assess the accuracy of the audio recordings captured by Pepper. Therefore, in this study, an experiment is conducted with eight participants with the primary objective of examining Pepper’s speech recognition system with the help of audio features such as Mel-Frequency Cepstral Coefficients, spectral centroid, spectral flatness, the Zero-Crossing Rate, pitch, and energy. Furthermore, the K-means algorithm was employed to create clusters based on these features with the aim of selecting the most suitable cluster with the help of the speech-to-text conversion tool Whisper. The selection of the best cluster is accomplished by finding the maximum accuracy data points lying in a cluster. A criterion of discarding data points with values of WER above 0.3 is imposed to achieve this. The findings of this study suggest that a distance of up to one meter from the humanoid robot Pepper is suitable for capturing the best speech recordings. In contrast, age and gender do not influence the accuracy of recorded speech. The proposed system will provide a significant strength in settings where subtitles are required to improve the comprehension of spoken statements.