Lorenzo Brigato

Dr. Lorenzo Brigato

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 April 2023 in Investigative Radiology
Verified
Journal Article
Open access
EDEthan Dack
Ethan Dack
ACAndreas Christe
Andreas Christe
MFMatthias Fontanellaz
Matthias Fontanellaz
LBLorenzo Brigato
Lorenzo Brigato
JHJohannes T. Heverhagen
Johannes T. Heverhagen
LELukas Ebner
Lukas Ebner
Interstitial lung disease (ILD) is now diagnosed by an ILD-board consisting of radiologists, pulmonologists, and pathologists. They discuss the combination of computed tomography (CT) images, pulmonary function tests, demographic information, and histology and then agree on one of the 200 ILD diagnoses. Recent approaches employ computer-aided diagnostic tools to improve detection of disease, monitoring, and accurate prognostication. Methods based on artificial intelligence (AI) may be used in computational medicine, especially in image-based specialties such as radiology. This review summarises and highlights the strengths and weaknesses of the latest and most significant published methods that could lead to a holistic system for ILD diagnosis. We explore current AI methods and the data use to predict the prognosis and progression of ILDs. It is then essential to highlight the data that holds the most information related to risk factors for progression, e.g., CT scans and pulmonary function tests. This review aims to identify potential gaps, highlight areas that require further research, and identify the methods that could be combined to yield more promising results in future studies.

5 May 2022 in IEEE Access
Verified
Journal Article
Open access
LBLorenzo Brigato
Lorenzo Brigato
BBBjörn Barz
Björn Barz
LILuca Iocchi
Luca Iocchi
Joachim DenzlerJoachim Denzler
Joachim Denzler
Image classification with small datasets has been an active research area in the recent past. However, as research in this scope is still in its infancy, two key ingredients are missing for ensuring reliable and truthful progress: a systematic and extensive overview of the state of the art, and a common benchmark to allow for objective comparisons between published methods. This article addresses both issues. First, we systematically organize and connect past studies to consolidate a community that is currently fragmented and scattered. Second, we propose a common benchmark that allows for an objective comparison of approaches. It consists of five datasets spanning various domains (e.g., natural images, medical imagery, satellite data) and data types (RGB, grayscale, multispectral). We use this benchmark to re-evaluate the standard cross-entropy baseline and ten existing methods published between 2017 and 2021 at renowned venues. Surprisingly, we find that thorough hyper-parameter tuning on held-out validation data results in a highly competitive baseline and highlights a stunted growth of performance over the years. Indeed, only a single specialized method dating back to 2019 clearly wins our benchmark and outperforms the baseline classifier.

2 September 2023 in Nutrients
Verified
Journal Article
Open access
PDF file
IPIoannis Papathanail
Ioannis Papathanail
LRLubnaa Abdur Rahman
Lubnaa Abdur Rahman
LBLorenzo Brigato
Lorenzo Brigato
NBNatalie S. Bez
Natalie S. Bez
MVMaria Vasiloglou
Maria Vasiloglou
Stavroula MougiakakouStavroula Mougiakakou
Stavroula Mougiakakou
A healthy diet can help to prevent or manage many important conditions and diseases, particularly obesity, malnutrition, and diabetes. Recent advancements in artificial intelligence and smartphone technologies have enabled applications to conduct automatic nutritional assessment from meal images, providing a convenient, efficient, and accurate method for continuous diet evaluation. We now extend the goFOODTM automatic system to perform food segmentation, recognition, volume, as well as calorie and macro-nutrient estimation from single images that are captured by a smartphone. In order to assess our system’s performance, we conducted a feasibility study with 50 participants from Switzerland. We recorded their meals for one day and then dietitians carried out a 24 h recall. We retrospectively analysed the collected images to assess the nutritional content of the meals. By comparing our results with the dietitians’ estimations, we demonstrated that the newly introduced system has comparable energy and macronutrient estimation performance with the previous method; however, it only requires a single image instead of two. The system can be applied in a real-life scenarios, and it can be easily used to assess dietary intake. This system could help individuals gain a better understanding of their dietary consumption. Additionally, it could serve as a valuable resource for dietitians, and could contribute to nutritional research.

2 May 2025
Verified
Book Chapter
Open access
PDF file
ZHZahra Hamedi
Zahra Hamedi
LBLorenzo Brigato
Lorenzo Brigato
EDEthan Dack
Ethan Dack
MSMira Schütz
Mira Schütz
BLBeat Lehmann
Beat Lehmann
GKGert Krummrey
Gert Krummrey
The goal of segmentation in abdominal imaging for emergency medicine is to accurately identify and delineate organs, as well as to detect and localize pathological areas. This precision is critical for rapid, informed decision-making in acute care scenarios. Vision foundation models, such as Segment Anything Model (SAM), have demonstrated remarkable results on many different segmentation tasks, but they perform poorly on medical images because of the scarcity of medical datasets. They lack robust generalizability across diverse medical imaging modalities, and they need to be fine-tuned specifically for medical images, as these images considerably differ from natural images. This study aims to investigate the application of a foundation segmentation model to ultrasound (US) images of the abdomen. We employed SAMed to segment and classify all organs and free fluid present in each US image. A dataset comprising 286 US images, corresponding segmentation masks, and organ-level labels was collected from the Bern University Hospital Inselspital. Due to the relatively small size of our dataset, we pre-trained SAMed on a larger public US dataset to fine-tune it for US imaging. We then applied this fine-tuned SAMed on the Inselspital dataset to generate multi-class masks and assessed its performance against ground truth annotations using standard evaluation metrics. The results demonstrated that the fine-tuned SAMed can identify and classify multiple organs, though challenging cases, such as free fluid segmentation, reveal opportunities for improvement. Furthermore, transfer learning proved to be a reliable solution for managing small datasets, a key obstacle in the medical imaging realm.

2 October 2023
Verified
Conference Paper
Open access
EDEthan Dack
Ethan Dack
LBLorenzo Brigato
Lorenzo Brigato
MMMatthew McMurray
Matthew McMurray
MFMatthias Fontanellaz
Matthias Fontanellaz
Thomas FrauenfelderThomas Frauenfelder
Thomas Frauenfelder
Stavroula MougiakakouStavroula Mougiakakou
Stavroula Mougiakakou
The pandemic resulted in vast repositories of unstructured data, including radiology reports, due to increased medical examinations. Previous research on automated diagnosis of COVID-19 primarily focuses on X-ray images, despite their lower precision compared to computed tomography (CT) scans. In this work, we leverage unstructured data from a hospital and harness the fine-grained details offered by CT scans to perform zero-shot multi-label classification based on contrastive visual language learning. In collaboration with human experts, we investigate the effectiveness of multiple zero-shot models that aid radiologists in detecting pulmonary embolisms and identifying intricate lung details like ground glass opacities and consolidations. Our empirical analysis provides an overview of the possible solutions to target such fine-grained tasks, so far overlooked in the medical multimodal pretraining literature. Our investigation promises future advancements in the medical image analysis community by addressing some challenges associated with unstructured data and fine-grained multi-label classification.