The incidence of both cataract and glaucoma is increasing globally. With increasing patient expectation and improved technology, premium intraocular lenses (IOLs), including presbyopia-correcting and toric IOLs, are being increasingly implanted today. However, concerns remain regarding the use of premium IOLs, particularly presbyopia-correcting IOLs, in eyes with glaucoma. This systematic review evaluates the use of premium IOLs in glaucoma. A comprehensive search of the MEDLINE database was performed from inception until 1 June 2023. Initial search yielded 1404 records, of which 12 were included in the final review of post-operative outcomes. Studies demonstrated high spectacle independence for distance and good patient satisfaction in glaucomatous eyes, with positive outcomes also in post-operative visual acuity, residual astigmatism, and contrast sensitivity. Considerations in patient selection include anatomical and functional factors, such as the type and severity of glaucomatous visual field defects, glaucoma subtype, presence of ocular surface disease, ocular changes after glaucoma surgery, and the reliability of disease monitoring, all of which may be affected by, or influence, the outcomes of premium IOL implantation in glaucoma patients. Regular reviews on this topic are needed in order to keep up with the rapid advancements in IOL technology and glaucoma surgical treatments.

Purpose: To evaluate the safety and effectiveness of the Ahmed ClearPath^® (ACP) 250 mm² glaucoma drainage device (GDD) in managing refractory primary open-angle glaucoma (POAG). Patients and Methods: This was a retrospective case series focused on adult patients diagnosed with severe POAG who underwent implantation of an ACP GDD. Over a 36-month follow-up period, data on intraocular pressure (IOP), the number of glaucoma medications, and complications were recorded. The primary objectives were to assess the reductions from baseline in both IOP and medication usage, through 36 months. Secondary objectives included the proportion of eyes achieving an IOP reduction of ≥ 20% from baseline at 36 months. Intraoperative and postoperative complications were also assessed. Results: Twelve eyes from 11 patients (mean age: 71.3 ± 14.1 years) met the inclusion criteria and were included in the study. All patients had severe POAG (n=11), with the majority being Caucasian (n=8) and female (n=10). The mean (standard deviation) IOP and number of glaucoma medications at baseline were 29 (7.6) mmHg and 3 (0.9), respectively. At 36 months, mean IOP was reduced to 10.6 (5.5) mmHg (− 61.8%; p= 0.0008) and mean number of medications was reduced to 0.9 (0.9) (− 71.4%; p=0.0005), with 88.9% of eyes achieving an IOP reduction by ≥ 20%. No vision threatening complications were observed. Conclusion: To our knowledge this is the first study to report 36-month outcomes of the novel ACP device in the treatment of refractory POAG. The safety profile and efficacy of the ACP was found to be comparable to that of other commonly utilized GDD models.

Purpose: To report clinical outcomes of successful excisional goniotomy with the Kahook Dual Blade (KDB), through 60 months. Patients and methods: This was a noncomparative, single-surgeon, retrospective review of eyes receiving successful KDB goniotomy with or without concomitant phacoemulsification between October 2015 and January 2016 with five years of uninterrupted follow-up. Intraocular pressure (IOP), number of glaucoma medications, best corrected visual acuity (BCVA), and complications were recorded. Primary outcomes included changes from baseline in IOP, medication use, and BCVA, through five years. Results: Fifty-two eyes of 28 patients were analyzed. Most eyes had mild primary open angle glaucoma (73%). Of the eyes analyzed, 41 underwent combined surgery and 11 underwent standalone surgery. With all eyes combined, mean (standard deviation) baseline IOP was 21.0 (4.1) mmHg and mean baseline medication use was 1.8 (1.1) medications per eye. Across time points at months 6, 12, 24, 36, 48, and 60, mean postoperative IOP ranged from 13.0 to 13.7 mmHg, representing mean reductions of 7.3– 8.0 mmHg (34.7– 38.3%; p < 0.0001 at every time point). Similarly, mean medication use ranged from 0.4 to 0.6 medications per eye, representing mean reductions of 1.2– 1.4 medications (66– 75.5%; p < 0.0001 at every time point). Mean logMAR BCVA improved from 0.321 (0.177) preoperatively to 0.015 (0.035) at month 60 (p < 0.0001). Conclusion: In eyes not requiring secondary surgical procedures (eg, long-term surgical successes), excisional goniotomy provided clinically and statistically significant reductions in both IOP and the need for medications that were highly consistent through five years of follow-up. KDB goniotomy appears to be highly successful in Caucasian patients with open angle glaucoma on ≥ 1 IOP-lowering medications at baseline and with no history of prior ocular surgery. Successful excisional goniotomy with the KDB can be expected to improve long-term glaucoma-related visual outcomes through IOP reduction and to improve quality of life through medication reduction.

Background: Mobile visual acuity (VA) apps have emerged as valuable tools in both clinical and home settings, particularly in the context of expanding teleophthalmology. Despite the growing number of apps available to measure visual acuity, studies evaluating their overall quality, functionality, and clinical relevance are limited. Objective: This study aimed to systematically evaluate the quality and features of mobile VA apps available on iOS and Android platforms using the clinically validated Mobile App Rating Scale (MARS). Methods: A comprehensive search of the Google Play Store and Apple App Store was conducted between January 2024 and March 2024 using standardized search terms. Eligible apps included free, English-language VA testing tools not requiring external devices. App characteristics and features were extracted. Each app was independently evaluated by 2 trained reviewers using MARS, which rates engagement, functionality, aesthetics, information quality, and subjective quality on a 5-point scale. Results: Of the 725 apps initially identified, 44 met the inclusion criteria, with 23 from the Google Play Store and 21 from the Apple App Store. The most common VA test optotypes used were Tumbling E (n=21; 48%), Snellen Chart (18/44; 41%), and Landolt C (n=14; 32%). Common supplemental features included color vision testing (n=20; 46%), astigmatism tests (n=13; 30%), Amsler grid (n=13; 30%), and contrast testing (n=12; 28%). The average MARS scores were comparable across platforms: 3.04 (SD 0.80) for Android and 3.02 (SD 0.84) for iOS. Functionality received the highest ratings (mean 3.65, SD 0.75 for Android; mean 3.71, SD 0.82 for iOS), while subjective quality received the lowest (mean 2.09, SD 1.01 for Android; mean 2.21, SD 1.01 for iOS). Few apps had undergone clinical validation. Only Apple App Store apps demonstrated significant correlations between MARS scores and app store star ratings. Conclusions: VA apps exhibited considerable heterogeneity in quality, functionality, and clinical use. Total mean MARS scores were similar between the Google Play Store and the Apple App Store, suggesting that neither platform consistently offers superior app quality. While many apps are technically sound, low subjective-quality scores and a lack of clinical validation limit their current use in professional practice. These findings underscore the need for more rigorous app development and validation standards to improve their relevance and reliability in teleophthalmology.

This study aimed to evaluate the safety profile and clinical efficacy of the VIA360™ Surgical System (VIA360) for ab-interno canaloplasty in the management of glaucoma. This retrospective, noncomparative chart review included 64 eyes undergoing standalone VIA360 ABiC (VIA360-Alone) or VIA360 combined with cataract surgery (VIA360–Cataract) between March 13, 2025, and January 7, 2026. Surgical success was defined as ≥20% intraocular pressure (IOP) reduction at the last follow-up without surgical reintervention. Changes in IOP, glaucoma medications, and best-corrected visual acuity (BCVA) were evaluated through 6 months. At 6 months, mean IOP decreased from 18.46 to 14.07 mmHg (−4.39 mmHg; −23.78%; P < 0.0001). In subgroup analysis, VIA360–Cataract eyes showed a reduction from 17.61 to 13.48 mmHg (−4.13 mmHg; −23.45%; P = 0.0011), while VIA360-Alone eyes decreased from 20.61 to 16.15 mmHg (−4.46 mmHg; −21.69%; P = 0.0549). Glaucoma medication use also decreased from 1.46 to 1.13 medications (−22.6%; P = 0.1331) overall at 6 months, with greater reductions observed in the combined group compared with standalone cases. Surgical success was achieved in 15 of 29 eyes (51.72%) with available follow-up. No intraoperative complications or vision-threatening adverse events were observed. These findings suggest that VIA360 provides clinically meaningful IOP reduction with an excellent safety profile in early postoperative outcomes, demonstrating greater consistency when performed in conjunction with cataract surgery. Larger prospective studies are warranted to further define long-term durability.