Some types of per- and poly-fluoroalkyl substances (PFAS) have been banned over the last two decades, but millions of Americans continue to have exposure to the compounds through drinking water and consumer products. Therefore, understanding the changes in serum PFAS concentrations after their limited use is necessary to protect public health. In this study, we evaluated trends of serum PFAS compounds (PFOS, PFOA, PFHxS, PFDA, and PFNA) to determine their distribution among the United States general population. We analyzed serum concentrations of PFAS measured from random subsamples of the National Health and Nutrition Examination Survey (NHANES) participants. The study results demonstrated that demographic factors such as race/ethnicity, age, and sex may influence the levels of serum PFAS over time. Adults, males, Asians, Non-Hispanic Blacks, and Non-Hispanic Whites had high risks of exposure to the selected PFAS. Overall, serum PFAS levels declined continuously in the studied population from 1999 to 2018. Among the studied population, PFOS and PFDA were the most and least prevalent PFAS in blood serum, respectively. Serum levels of PFDA, PFOA, and PFHxS showed upward trends in at least one racial/ethnic group after 2016, which underscores the need for continuous biomonitoring of PFAS levels in humans and the environment.

Human health is threatened by antibiotic-resistant bacteria and their related infections, which cause thousands of human deaths every year worldwide. Surface waters are vulnerable to human activities and natural processes that facilitate the emergence and spread of antibiotic-resistant bacteria in the environment. This study evaluated the pathways and drivers of antimicrobial resistance (AR) in surface waters. We analyzed antibiotic resistance healthcare-associated infection (HAI) data reported to the CDC’s National Healthcare Safety Network to determine the number of antimicrobial-resistant pathogens and their isolates detected in healthcare facilities. Ten pathogens and their isolates associated with HAIs tested resistant to the selected antibiotics, indicating the role of healthcare facilities in antimicrobial resistance in the environment. The analyzed data and literature research revealed that healthcare facilities, wastewater, agricultural settings, food, and wildlife populations serve as the major vehicles for AR in surface waters. Antibiotic residues, heavy metals, natural processes, and climate change were identified as the drivers of antimicrobial resistance in the aquatic environment. Food and animal handlers have a higher risk of exposure to resistant pathogens through ingestion and direct contact compared with the general population. The AR threat to public health may grow as pathogens in aquatic systems adjust to antibiotic residues, contaminants, and climate change effects. The unnecessary use of antibiotics increases the risk of AR, and the public should be encouraged to practice antibiotic stewardship to decrease the risk.

Utilised in a variety of consumer products, per- and polyfluoroalkyl substances (PFAS) are major environmental contaminants that accumulate in living organisms due to their highly hydrophobic, lipophobic, heat-resistant, and non-biodegradable properties. This review summarizes their effects on microbial populations in soils, aquatic and biogeochemical systems, and the human microbiome. Specific microbes are insensitive to and even thrive with PFAS contamination, such as Escherichia coli and the Proteobacteria in soil and aquatic environments, while some bacterial species, such as Actinobacteria and Chloroflexi , are sensitive and drop in population. Some bacterial species, in turn, have shown success in PFAS bioremediation, such as Acidimicrobium sp . and Pseudomonas parafulva .

Plastic pollution poses a critical global environmental threat, with Nigeria being particularly vulnerable to this due to its rapid industrialization, urbanization, and inadequate waste management infrastructure. This study investigated public awareness and perceptions of plastic pollution in Nigeria, emphasizing the ecological impacts and potential economic opportunities associated with plastic waste. Using a comprehensive questionnaire administered from June to December 2023, the study evaluated the extent of public awareness, perceptions of responsibility, and key factors influencing attitudes towards the management of plastic waste. The findings revealed a high level of public awareness about plastic pollution, with 66.5% of respondents having participated in environment-related gatherings and 56.5% were familiar with the concept of a circular economy. A significant majority (79.2%) believed in the wealth-generating potential of plastic waste, highlighting methods such as recycling, energy generation, and manufacturing new products. The study also identified significant associations between socio-demographic factors and perceptions of responsibility for plastic pollution management. The study underscores the need for targeted education and policy interventions to address disparities influenced by socio-demographic factors. The potential for economic development through recycling and innovative waste management solutions, such as pyrolysis and gasification, is emphasized. Effective collaboration among government agencies, businesses, NGOs, and local communities is essential to develop infrastructure, implement supportive policies, and promote responsible waste disposal practices. The results highlight the dual opportunity for economic growth and environmental protection through sustainable waste management. Advancing circular economy initiatives in Nigeria requires innovative solutions, stakeholder collaboration, and policies that leverage the wealth-generating potential of plastic waste while safeguarding the environment.