Mihaela Matovina

Dr. Mihaela Matovina

Division of Organic Chemistry and Biochemistry, Rudjer Boskovic Institute, Zagreb, Zagreb, Grad, Croatia
orcid

Research Focus & Metrics

Academic Career Length

24Years (2003-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 March 2004 in Fertility and Sterility
Verified
Journal Article
Closed access
Mihaela MatovinaMihaela Matovina
Mihaela Matovina
KHKoraljka Husnjak
Koraljka Husnjak
Nina Milutin GašperovNina Milutin Gašperov
Nina Milutin Gašperov
SCSrecko Ciglar
Srecko Ciglar
MGMagdalena Grce
Magdalena Grce

1 April 2009 in Gynecologic Oncology
Verified
Journal Article
Closed access
Mihaela MatovinaMihaela Matovina
Mihaela Matovina
Ivan SabolIvan Sabol
Ivan Sabol
GGGoran Grubišić
Goran Grubišić
Nina Milutin GašperovNina Milutin Gašperov
Nina Milutin Gašperov
MGMagdalena Grce
Magdalena Grce


1 June 2015 in Microbial Drug Resistance
Verified
Journal Article
Closed access
MBMarina Bubonja-Sonje
Marina Bubonja-Sonje
Mihaela MatovinaMihaela Matovina
Mihaela Matovina
ISIvana Skrobonja
Ivana Skrobonja
BBBranka Bedenic
Branka Bedenic
MAMaja Abram
Maja Abram
Pseudomonas aeruginosa is an opportunistic pathogen, one of the leading causes of nosocomial infections such as pneumonia, urinary tract infections, and bacteraemia. The bacterial resistance to structurally unrelated antibiotics and its spread within hospitals limits the efficient antimicrobial options and patients' outcome. Carbapenems are important agents for the therapy of infections due to multidrug-resistant (MDR) P. aeruginosa ; hence, the development of carbapenem resistance severely hampers effective therapeutic options. The aim of this investigation was to examine mechanisms of carbapenem resistance and genomic diversity in carbapenem-resistant MDR strains of P. aeruginosa , which caused an outbreak among patients in Clinical Hospital Rijeka. Most of the isolates showed decreased expression of porin that is important for the entry of carbapenems ( oprD ). Overexpression of MexAB-OprM, MexCD-OprJ, and MexEF-OprN efflux systems was observed in many of the isolates. Production of metallo-β-lactamases was not detected. Typing by pulsed-field gel electrophoresis discriminated the isolates into five clusters. The clonal distribution of the strains was related to the location of hospital departments where the isolates were collected, which implies that most of the infections were caused by spread of the epidemic strains within the hospital.

1 February 2011 in Toxicology in Vitro
Verified
Journal Article
Closed access
MPMarija Poljak-Blazi
Marija Poljak-Blazi
MJMorana Jaganjac
Morana Jaganjac
Ivan SabolIvan Sabol
Ivan Sabol
BMBranka Mihaljevic
Branka Mihaljevic
Mihaela MatovinaMihaela Matovina
Mihaela Matovina
MGMagdalena Grce
Magdalena Grce

1 March 2004 in Journal of Clinical Microbiology
Verified
Journal Article
Open access
PDF file
MGMagdalena Grce
Magdalena Grce
KHKoraljka Husnjak
Koraljka Husnjak
Mihaela MatovinaMihaela Matovina
Mihaela Matovina
Nina Milutin GašperovNina Milutin Gašperov
Nina Milutin Gašperov
LML. Magdic
L. Magdic
Krešimir PavelićKrešimir Pavelić
Krešimir Pavelić
Two hundred eight cervical specimens from two groups of subjects, 165 nonpregnant women and 53 pregnant women with cervical intraepithelial neoplasia (CIN) of grades I to III, were positive by PCR analyses for human papillomaviruses (HPVs), adeno-associated virus type 2 (AAV 2), and human cytomegalovirus (HCMV) in 67, 6, and 4.1% of the cases, respectively. The presence of AAV 2 infection was more frequently associated with pregnancy (17 versus 2.4%) and HPV-positive cervices (odds ratio = 6.358) than HCMV was. Increased HPV infection was strongly associated ( P < 0.001) with a higher CIN grade, but there is no evidence that AAV 2 and HCMV infections have any impact on CIN development.