This study aimed to evaluate the effectiveness of early intervention (EI) for infants at high risk for cerebral palsy (CP), particularly in the context of their neurological development. The study was conducted at the Regional Perinatal Center in Aktobe, Kazakhstan, and included 69 preterm infants with adverse neonatal periods. The infants were divided into two groups: the first group (n=50) began EI at 42 weeks postmenstrual age, while the second group (n=19) started at 52 weeks. Both groups underwent general movements assessment (GMA) and motor activity monitoring using general movement optimality score (GMOS). Results showed that infants receiving EI earlier demonstrated significant improvements in movement quality and a reduced risk of adverse neurological outcomes compared to the control group. The findings highlight the importance of early detection and intervention, as well as the need for implementing early diagnostic programs for infants at risk.

The well-being of children is crucial for a nation’s demographic, economic, and intellectual prospects. Developing countries face an increasing number of children with disabilities, primarily attributed to congenital developmental defects, neurological disorders, and other health issues. Neurological disorders pose significant challenges to realizing the full potential of children and society. Early intervention is essential for improving functional outcomes in infants with neurological impairments. General Movements (GM) assessment, a predictor of subsequent neurological outcomes, plays a vital role in early detection. However, its widespread implementation in developing countries is limited. This article explores the history of GM assessment, its current state in developing countries, and the potential for mobile applications to revolutionize early assessments and interventions in developing countries.

Study Evaluation: The bibliometric analysis of the published results of the alpha‐synuclein ( α ‐syn) detection study in the peripheral tissues of patients with Parkinson’s disease was carried out by us to study scientific activity and scientific productivity, to measure the quantitative and qualitative characteristics of scientific publications, author productivity, and citation of works, as well as the degree of interrelation between authors, journals, institutes, and countries. Purpose: This study is aimed at bibliometrically analyzing the results of studies on the detection of α ‐syn in peripheral tissue biopsy of patients with Parkinson’s disease from 2013 to 2023. Methods: The data was extracted from the Scopus database collection using an inclusive search strategy. Performance analysis and science mapping were conducted using RStudio v.4.3.1 with the bibliometrix R‐package. The analyzed data encompassed trends in publication and citation and the identification of leading institutions, primary sources, authors, and collaborative countries. Results: A total of 124 relevant studies from 53 different sources were thoroughly analyzed. The analysis included the materials of 843 authors, which together gave an impressive average of 37.67 citations per document over the past decade. The annual growth rate in this area of research, according to calculations, was 10.84%, indicating a steady increase in the number of publications over the study period. The huge volume of research results is highlighted by the inclusion of 231 unique keywords of authors. Conclusion: Studies on the detection of pathological α ‐syn in peripheral tissues for early morphological verification of the diagnosis of Parkinson’s disease are relevant in clinical neurology. α ‐syn detected in the skin biopsy of patients on the basis of this study and data from the world literature meets the requirements for biomarkers.

Tandem mass spectrometry (MS/MS) for diagnosing inborn errors of metabolism (IEM) is recognized as an ethical, safe, simple, and reliable screening test. Presented bibliometric analysis aims to describe the network structure of the scientific community in the study area at the level of countries, institutions, authors, papers, keywords, and sources; scientific productivity, directions, and collaboration efforts in a considered period (1991–2023.) Using the PRISMA method, we conducted a systematic search for articles reporting using MS/MS to screen for inherited metabolic disorders and inborn errors of metabolism collected from the Web of Science Core Collection (WOSCC.) A total of 451 articles out of 546, by 2,682 authors, published in 190 journals, with 15,440 citations in 8,181 citing articles, with an average citation of 34.24 per article, and an H-index of 64 were retrieved from the WOSCC. The research status of MS/MS in IEM screening was identified. The most relevant current research directions and future areas of interest were revealed: "selective screening for IEM," "new treatments for IEM," "new disorders considered for MS/MS testing," "ethical issues associated with newborn screening," "new technologies that may be used for newborn screening," "use of a combination of MS/MS and gene sequencing," etc.